Chiral separation of mandelic acid by temperature-induced aqueous two-phase system

2012 ◽  
Vol 87 (3) ◽  
pp. 346-350 ◽  
Author(s):  
Jian-min Xing ◽  
Fen-fang Li
Keyword(s):  
Chiral Separation ◽  
Mandelic Acid ◽  
Phase System ◽  
Two Phase ◽  
Aqueous Two Phase System

Preparative chiral separation in an aqueous two-phase system by a few counter-current extractions

1988 ◽  
Vol 450 (3) ◽  
pp. 277-280 ◽  
Author(s):  
Börje Sellergren ◽  
Björn Ekberg ◽  
Per-Åke Albertsson ◽  
Klaus Mosbach
Keyword(s):  
Chiral Separation ◽  
Phase System ◽  
Two Phase ◽  
Aqueous Two Phase System ◽  
Counter Current

Enantioseparation of mandelic acid and α-cyclohexylmandelic acid using an alcohol/salt-based aqueous two-phase system

2014 ◽  
Vol 68 (11) ◽  
Author(s):  
Fen-Fang Li ◽  
Zhi-Jian Tan ◽  
Zhi-Feng Guo
Keyword(s):  
Mandelic Acid ◽  
Chiral Recognition ◽  
Scale Up ◽  
Chiral Selector ◽  
Phase System ◽  
Optimal Conditions ◽  
Two Phase ◽  
Experimental Conditions ◽  
Aqueous Two Phase System ◽  
Recognition Ability

AbstractAn alcohol/salt-based aqueous two-phase system (ATPS) was employed for enantioseparation of (R,S)-mandelic acid (MA) and (R,S)-α-cyclohexylmandelic acid (α-CHMA). Sulfonated β-cyclodextrin (Sf-β-CD) with different degrees of substitution (DS) was considered as the chiral selector. The ethanol/(NH4)2SO4 system showed the optimal chiral recognition ability for MA. To optimize the experimental conditions, Sf-β-CD concentration, ethanol and salt concentration, temperature, and pH were studied. The recognition ability of enantiomers was mainly dependent on the type of the chiral selector but the ethanol and (NH4)2SO4 concentrations also had significant influence on the enantiomeric recognition. The maximum values of α and ee up of 1.69 and 16.3 % were obtained, respectively, for MA under the optimal conditions. A potential application of this alcohol/salt ATPS is the scale-up of chiral separation of MA.

Chiral separation of α-cyclohexylmandelic acid enantiomers using ionic liquid/salt aqueous two-phase system

2015 ◽  
Vol 69 (11) ◽  
Author(s):  
Lei-Lei Chen ◽  
Fen-Fang Li ◽  
Zhi-Jian Tan
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Chiral Separation ◽  
Mixing Time ◽  
Chiral Selector ◽  
Phase System ◽  
Two Phase ◽  
Aqueous Two Phase System ◽  
Liquid Salt ◽  
Influencing Parameters

AbstractIn this paper, an ionic liquid-based aqueous two-phase system (ILATPS) was applied to the chiral separation of α-cyclohexylmandelic acid (α-CHMA) enantiomers with hydroxypropyl-β- cyclodextrin (HP-β-CD) as the chiral selector. Several influencing parameters were investigated including the types and concentration of ionic liquids, the amount of phase-forming salt, temperature, mixing time, pH, and the content of HP-β-CD. The results showed that not all ILATPS had the ability to chirally recognise the selected enantiomers and that [C

Enhancing the Sensitivity of DNA and Aptamer Probes in the Dextran/PEG Aqueous Two-Phase System

2021 ◽  
Author(s):  
Qiaoshu Chen ◽  
Yanwen Zhang ◽  
Hui Chen ◽  
Jianbo Liu ◽  
Juewen Liu
Keyword(s):  
Phase System ◽  
Two Phase ◽  
Aqueous Two Phase System

Continuous Purification of an Enveloped and Non-enveloped Viral Particle Using an Aqueous Two-Phase System

2021 ◽  
pp. 118753
Author(s):  
Dylan G. Turpeinen ◽  
Pratik U. Joshi ◽  
Seth A. Kriz ◽  
Supreet Kaur ◽  
Natalie M. Nold ◽  
...  
Keyword(s):  
Viral Particle ◽  
Phase System ◽  
Two Phase ◽  
Aqueous Two Phase System

scholarly journals Partitioning of bovine lactoferrin in aqueous two-phase system containing poly(ethylene glycol) and sodium citrate

2015 ◽  
Vol 95 ◽  
pp. 118-124 ◽  
Author(s):  
Angélica Ribeiro da Costa ◽  
Jane Sélia dos Reis Coimbra ◽  
Luísa Alexandre Ferreira ◽  
João Carlos Marcos ◽  
Igor José Boggione Santos ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Sodium Citrate ◽  
Bovine Lactoferrin ◽  
Phase System ◽  
Poly Ethylene Glycol ◽  
Two Phase ◽  
Aqueous Two Phase System ◽  
Poly Ethylene
Sign in / Sign up

Export Citation Format

Share Document