scholarly journals Using lysis therapy to treat five critically ill COVID‐19 patients who show echocardiographic criteria of right ventricular strain

eJHaem ◽  
2021 ◽  
Author(s):  
Ahmed Mahdy ◽  
Eslam Abbas ◽  
Rawad Tarek ◽  
Nawar Jabbour ◽  
Huda Al‐Foudri
Keyword(s):  
Right Ventricular ◽  
Critically Ill ◽  
Right Ventricular Strain ◽  
Lysis Therapy

scholarly journals Right Ventricular Strain Is Common in Intubated COVID-19 Patients and Does Not Reflect Severity of Respiratory Illness

2021 ◽  
pp. 088506662110063
Author(s):  
Lauren E. Gibson ◽  
Raffaele Di Fenza ◽  
Min Lang ◽  
Martin I. Capriles ◽  
Matthew D. Li ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Disease Severity ◽  
Critically Ill ◽  
Lung Compliance ◽  
Left Ventricular ◽  
Lung Mechanics ◽  
Chest Imaging ◽  
Imaging Findings ◽  
Right Ventricular Strain ◽  
Ventilatory Parameters

Background: Right ventricular (RV) dysfunction is common and associated with worse outcomes in patients with coronavirus disease 2019 (COVID-19). In non-COVID-19 acute respiratory distress syndrome, RV dysfunction develops due to pulmonary hypoxic vasoconstriction, inflammation, and alveolar overdistension or atelectasis. Although similar pathogenic mechanisms may induce RV dysfunction in COVID-19, other COVID-19-specific pathology, such as pulmonary endothelialitis, thrombosis, or myocarditis, may also affect RV function. We quantified RV dysfunction by echocardiographic strain analysis and investigated its correlation with disease severity, ventilatory parameters, biomarkers, and imaging findings in critically ill COVID-19 patients. Methods: We determined RV free wall longitudinal strain (FWLS) in 32 patients receiving mechanical ventilation for COVID-19-associated respiratory failure. Demographics, comorbid conditions, ventilatory parameters, medications, and laboratory findings were extracted from the medical record. Chest imaging was assessed to determine the severity of lung disease and the presence of pulmonary embolism. Results: Abnormal FWLS was present in 66% of mechanically ventilated COVID-19 patients and was associated with higher lung compliance (39.6 vs 29.4 mL/cmH2O, P = 0.016), lower airway plateau pressures (21 vs 24 cmH2O, P = 0.043), lower tidal volume ventilation (5.74 vs 6.17 cc/kg, P = 0.031), and reduced left ventricular function. FWLS correlated negatively with age (r = −0.414, P = 0.018) and with serum troponin (r = 0.402, P = 0.034). Patients with abnormal RV strain did not exhibit decreased oxygenation or increased disease severity based on inflammatory markers, vasopressor requirements, or chest imaging findings. Conclusions: RV dysfunction is common among critically ill COVID-19 patients and is not related to abnormal lung mechanics or ventilatory pressures. Instead, patients with abnormal FWLS had more favorable lung compliance. RV dysfunction may be secondary to diffuse intravascular micro- and macro-thrombosis or direct myocardial damage. Trial Registration: National Institutes of Health #NCT04306393. Registered 10 March 2020, https://clinicaltrials.gov/ct2/show/NCT04306393

scholarly journals Speckle tracking echocardiography in primary mitral regurgitation: should we reconsider the time for intervention?

2021 ◽  
Author(s):  
Maria Concetta Pastore ◽  
Giulia Elena Mandoli ◽  
Aleksander Dokollari ◽  
Gianluigi Bisleri ◽  
Flavio D’Ascenzi ◽  
...  
Keyword(s):  
Mitral Regurgitation ◽  
Right Ventricular ◽  
Speckle Tracking ◽  
Speckle Tracking Echocardiography ◽  
Right Ventricular Dysfunction ◽  
Left Ventricular ◽  
Main Concern ◽  
Cardiac Damage ◽  
Asymptomatic Patients ◽  
Right Ventricular Strain

Abstract Thanks to the improvement in mitral regurgitation (MR) diagnostic and therapeutic management, with the introduction of minimally invasive techniques which have considerably reduced the individual surgical risk, the optimization of the timing for MR “open” or percutaneous surgical treatment has become a main concern which has highly raised scientific interest. In fact, the current indications for intervention in MR, especially in asymptomatic patients, rely on echocardiographic criteria with high severity cut-offs that are fulfilled only when not only mitral valve apparatus but also the cardiac chambers’ structure and function are severely impaired, which results in poor benefits for post-operative clinical outcome. This led to the need of new indices to redefine the optimal surgical timing in these patients. Speckle tracking echocardiography provides early markers of cardiac dysfunction due to subtle myocardial impairment; therefore, it could offer pivotal information in this setting. In fact, left ventricular and left atrial strains have already shown evidence about their usefulness in recognizing MR impact not only on symptoms and quality of life but also on cardiovascular events and new-onset atrial fibrillation in these patients. Moreover, right ventricular strain could be used to identify those patients with advanced cardiac damage and different grades of right ventricular dysfunction, which entails higher risks for cardiac surgery that could overweigh surgical benefits. This review aims to describe the importance of reconsidering the timing of intervention in MR and to analyze the potential additive value of speckle tracking echocardiography in this clinical setting.

Normal ventricular diameter ratio on CT provides adequate assessment for critical right ventricular strain among patients with acute pulmonary embolism

2016 ◽  
Vol 32 (7) ◽  
pp. 1153-1161 ◽  
Author(s):  
Kanako K. Kumamaru ◽  
Elizabeth George ◽  
Nina Ghosh ◽  
Carlos Gonzalez Quesada ◽  
Nicole Wake ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Right Ventricular ◽  
Acute Pulmonary Embolism ◽  
Diameter Ratio ◽  
Right Ventricular Strain

Right ventricular strain

2018 ◽  
Vol 33 (5) ◽  
pp. 486-492 ◽  
Author(s):  
Bilal Ayach ◽  
Nowell M. Fine ◽  
Lawrence G. Rudski
Keyword(s):  
Right Ventricular ◽  
Right Ventricular Strain

scholarly journals Incremental Prognostic Value of Right Ventricular Strain in Patients With Acute Decompensated Heart Failure

2018 ◽  
Vol 11 (10) ◽  
Author(s):  
Yoshie Hamada-Harimura ◽  
Yoshihiro Seo ◽  
Tomoko Ishizu ◽  
Isao Nishi ◽  
Tomoko Machino-Ohtsuka ◽  
...  
Keyword(s):  
Heart Failure ◽  
Right Ventricular ◽  
Prognostic Value ◽  
Acute Decompensated Heart Failure ◽  
Decompensated Heart Failure ◽  
Right Ventricular Strain ◽  
Incremental Prognostic Value

scholarly journals Right ventricular strain and strain rate and pulmonary function before and after percutaneous baloon mitral valvuloplasty in patients with severe rheumatic mitral stenosis

2018 ◽  
Vol 70 ◽  
pp. S16
Author(s):  
Praveen Kumar Reddy Sakkuru ◽  
D. Rajasekhar ◽  
V. Vanajakshamma ◽  
A.T. Naresh ◽  
Narendra ◽  
...  
Keyword(s):  
Pulmonary Function ◽  
Right Ventricular ◽  
Strain Rate ◽  
Mitral Stenosis ◽  
Mitral Valvuloplasty ◽  
Rheumatic Mitral Stenosis ◽  
Strain And Strain Rate ◽  
Right Ventricular Strain ◽  
Before And After

scholarly journals EkoSonic™ Endovascular System-Directed Thrombolysis in a Patient With COVID-19 Infection Presenting With Bilateral Large Pulmonary Embolism Causing Right Ventricular Strain: A Case Report

Cureus ◽  
2022 ◽  
Author(s):  
Zahid Khan ◽  
Animesh Gupta ◽  
Umesh Kumar Pabani ◽  
Sunaina Lohano ◽  
Gideon Mlawa
Keyword(s):  
Pulmonary Embolism ◽  
Case Report ◽  
Right Ventricular ◽  
Right Ventricular Strain

scholarly journals Prognostic of the right ventricular strain in organic mitral regurgitation

2018 ◽  
Vol 10 (1) ◽  
pp. 51-52
Author(s):  
A. Jobbe Duval ◽  
M. Poilane ◽  
O. Thebault ◽  
C. Cueff ◽  
N. Piriou ◽  
...  
Keyword(s):  
Mitral Regurgitation ◽  
Right Ventricular ◽  
Right Ventricular Strain ◽  
The Right

scholarly journals Doppler Interrogation of the Femoral Vein in the Critically Ill Patient: The Fastest Potential Acoustic Window to Diagnose Right Ventricular Dysfunction?

2020 ◽  
Vol 2 (10) ◽  
pp. e0209
Author(s):  
André Y. Denault ◽  
Matthew P. Aldred ◽  
Ali Hammoud ◽  
Yu Hao Zeng ◽  
William Beaubien-Souligny ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Critically Ill ◽  
Ventricular Dysfunction ◽  
Femoral Vein ◽  
Right Ventricular Dysfunction ◽  
Critically Ill Patient ◽  
Acoustic Window
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