scholarly journals Rare additional chromosomal abnormalities in acute promyelocytic leukaemia resulting in rapidly fatal disease: report of a case

eJHaem ◽  
2021 ◽  
Author(s):  
Ahmed Maseh Haidary ◽  
Sarah Noor ◽  
Sahar Noor ◽  
Maryam Ahmad ◽  
Ahmad Walid Yousufzai ◽  
...  
Keyword(s):  
Acute Promyelocytic Leukaemia ◽  
Chromosomal Abnormalities ◽  
Promyelocytic Leukaemia ◽  
Fatal Disease ◽  
Additional Chromosomal Abnormalities

Additional chromosomal abnormalities in patients with acute promyelocytic leukaemia (APL) do not confer poor prognosis: results of APL 93 trial

2000 ◽  
Vol 111 (3) ◽  
pp. 801-806 ◽  
Author(s):  
Stephane de Botton ◽  
Sylvie Chevret ◽  
Miguel Sanz ◽  
Herve Dombret ◽  
Xavier Thomas ◽  
...  
Keyword(s):  
Acute Promyelocytic Leukaemia ◽  
Poor Prognosis ◽  
Chromosomal Abnormalities ◽  
Promyelocytic Leukaemia ◽  
Additional Chromosomal Abnormalities

scholarly journals Additional chromosomal abnormalities in patients with acute promyelocytic leukaemia (APL) do not confer poor prognosis: results of APL 93 trial

2000 ◽  
Vol 111 (3) ◽  
pp. 801-806 ◽  
Author(s):  
Stéphane de Botton ◽  
Sylvie Chevret ◽  
Miguel Sanz ◽  
Hervé Dombret ◽  
Xavier Thomas ◽  
...  
Keyword(s):  
Acute Promyelocytic Leukaemia ◽  
Poor Prognosis ◽  
Chromosomal Abnormalities ◽  
Promyelocytic Leukaemia ◽  
Additional Chromosomal Abnormalities

Chromosomal Abnormalities in Acute Promyelocytic Leukaemia

2009 ◽  
Vol 26 (1) ◽  
pp. 57-60 ◽  
Author(s):  
Albert de la Chapelle ◽  
Sakari Knuutila ◽  
Erkki Elonen ◽  
Pekka Vuopio
Keyword(s):  
Acute Promyelocytic Leukaemia ◽  
Chromosomal Abnormalities ◽  
Promyelocytic Leukaemia

scholarly journals Recent advances in acute promyelocytic leukaemia

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 1273 ◽  
Author(s):  
Chin-Hin Ng ◽  
Wee-Joo Chng
Keyword(s):  
Targeted Therapy ◽  
Acute Promyelocytic Leukaemia ◽  
Fusion Gene ◽  
Promyelocytic Leukaemia ◽  
Fatal Disease ◽  
The Past ◽  
Trans Retinoic Acid ◽  
Recent Advances ◽  
All Trans Retinoic Acid ◽  
New Treatment

Acute promyelocytic leukaemia (APML) is a subtype of leukaemia arising from a distinct reciprocal translocation involving chromosomes 15 and 17, which results in thePML-RARAfusion gene. Over the past three decades, APML has been transformed from a highly fatal disease to a highly curable one. This drastic improvement is because of the introduction of a new treatment strategy with all-trans retinoic acid and, more recently, arsenic trioxide. The revolutionary treatment of APML has also paved the way for a new cancer treatment, which is genetically targeted therapy. In this review, we look into this amazing journey of transformation and provide recent advances in the management of APML.

scholarly journals A novel HNRNPC‐RARA fusion in acute promyelocytic leukaemia lacking PML‐RARA rearrangement, sensitive to venetoclax‐based therapy

2021 ◽  
Author(s):  
Meng Liu ◽  
Xiujie Zhao ◽  
Wenjue Pan ◽  
Zijun Qian ◽  
Mengbao Du ◽  
...  
Keyword(s):  
Acute Promyelocytic Leukaemia ◽  
Promyelocytic Leukaemia

scholarly journals Rapidly progressing, fatal and acute promyelocytic leukaemia that initially manifested as a painful third molar: a case report

2009 ◽  
Vol 3 (1) ◽  
Author(s):  
Juan A Suárez-Cuenca ◽  
José L Arellano-Sánchez ◽  
Aldo A Scherling-Ocampo ◽  
Gerardo Sánchez-Hernández ◽  
David Pérez-Guevara ◽  
...  
Keyword(s):  
Case Report ◽  
Acute Promyelocytic Leukaemia ◽  
Third Molar ◽  
Promyelocytic Leukaemia

Atypical presentation of therapy-related acute promyelocytic leukaemia with marrow fibrosis

Pathology ◽  
2016 ◽  
Vol 48 (3) ◽  
pp. 286-288 ◽  
Author(s):  
Muhajir Mohamed ◽  
Harry J. Iland ◽  
Sharad Sharma ◽  
Shane G. Supple
Keyword(s):  
Acute Promyelocytic Leukaemia ◽  
Promyelocytic Leukaemia ◽  
Atypical Presentation ◽  
Marrow Fibrosis

TRAIL leads to apoptosis in acute promyelocytic leukaemia

The Lancet ◽  
2001 ◽  
Vol 357 (9270) ◽  
pp. 1770 ◽  
Author(s):  
Jane Bradbury
Keyword(s):  
Acute Promyelocytic Leukaemia ◽  
Promyelocytic Leukaemia
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