This article examines the effects of cardiovascular diseases that alter the diameter, wall thickness, and length of blood vessels. Depending on form and size of the damage, blood flow velocity, blood pressure, and stresses are affected in areas of diseased blood vessels. Through stimulating the deviations in the geometric shape of a blood-vessel wall, local blood pressure and stresses can arise from flow variation of blood vessels. This rise affects the blood-vessel wall and causes critical stresses likely to produce fissures in the blood vessels. It was found, that blood vessel pathology could cause blood flow velocity to increase up to 2.2 times and local blood pressure up to 3.4 times, and that human aging may have a significant influence on blood-vessel strength.
Distribution of blood flow velocity in the normal aorta: Effect of age and gender
