A UFLC-MS/MS method with a switching ionization mode for simultaneous quantitation of polygalaxanthone III, four ginsenosides and tumulosic acid in rat plasma: application to a comparative pharmacokinetic study in normal and Alzheimer's disease rats

2013 ◽  
Vol 48 (8) ◽  
pp. 904-913 ◽  
Author(s):  
Chunxiao Lv ◽  
Qing Li ◽  
Yaowen Zhang ◽  
Zhenyu Sui ◽  
Bosai He ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Pharmacokinetic Study ◽  
Rat Plasma ◽  
Comparative Pharmacokinetic ◽  
Ionization Mode

UPLC-MS/MS method for determination of schisandrin in rat plasma and brain microdialysates: application to a comparative pharmacokinetic and brain distribution study in normal and Alzheimer’s disease rats

2017 ◽  
Vol 9 (32) ◽  
pp. 4740-4746 ◽  
Author(s):  
BinBin Wei ◽  
Mingyan Liu ◽  
Zaixing Chen ◽  
Minjie Wei
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Rat Plasma ◽  
Brain Distribution ◽  
Comparative Pharmacokinetic ◽  
Distribution Study

An efficient UPLC-MS/MS method for determining schisandrin in rat plasma and brain microdialysates has been developed and validated.

P1-254: A safety, tolerability and pharmacokinetic study of dimebon in patients with Alzheimer's disease already receiving donepezil

2009 ◽  
Vol 5 (4S_Part_8) ◽  
pp. P251-P251 ◽  
Author(s):  
Pierre Tariot ◽  
Marwan Sabbagh ◽  
Stephen Flitman ◽  
Patricio Reyes ◽  
Louise Taber ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Pharmacokinetic Study
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