Correlational analysis of chemokine and inflammatory cytokine expression in the intervertebral disc and blood in patients with lumbar disc disease

2021 ◽  
Author(s):  
Akihiko Hiyama ◽  
Kaori Suyama ◽  
Daisuke Sakai ◽  
Masahiro Tanaka ◽  
Masahiko Watanabe
Keyword(s):  
Intervertebral Disc ◽  
Inflammatory Cytokine ◽  
Lumbar Disc ◽  
Correlational Analysis ◽  
Cytokine Expression ◽  
Disc Disease ◽  
Lumbar Disc Disease

Preoperative paraspinal and psoas major muscle atrophy and paraspinal muscle fatty degeneration as factors influencing the results of surgical treatment of lumbar disc disease

2021 ◽  
Author(s):  
Agnieszka Stanuszek ◽  
Adrian Jędrzejek ◽  
Eliza Gancarczyk-Urlik ◽  
Izabela Kołodziej ◽  
Magdalena Pisarska-Adamczyk ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Muscle Atrophy ◽  
Lumbar Disc ◽  
Fatty Degeneration ◽  
Paraspinal Muscle ◽  
Disc Disease ◽  
Lumbar Disc Disease ◽  
Factors Influencing ◽  
Psoas Major Muscle ◽  
Psoas Major

scholarly journals Does the Intradiscal Injection of Platelet Rich Plasma Have Any Beneficial Role in the Management of Lumbar Disc Disease?

2021 ◽  
pp. 219256822199836
Author(s):  
Sathish Muthu ◽  
Madhan Jeyaraman ◽  
Girinivasan Chellamuthu ◽  
Naveen Jeyaraman ◽  
Rashmi Jain ◽  
...  
Keyword(s):  
Beneficial Effect ◽  
Platelet Rich Plasma ◽  
Lumbar Disc ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Significant Heterogeneity ◽  
Disc Disease ◽  
Lumbar Disc Disease ◽  
Beneficial Role ◽  
Sf 36

Study Design: Systematic review and meta-analysis. Objectives: We performed this meta-analysis to evaluate whether intradiscal Platelet Rich Plasma(PRP) injection has any beneficial role in the management of lumbar disc disease. Methods: We conducted independent and duplicate electronic database searches including PubMed, Embase, and Cochrane Library till September 2020 for studies investigating the role of intradiscal PRP in the management of lumbar disc disease. The analysis was performed in the R platform using OpenMeta[Analyst] software. Results: 13 studies including 2 RCTs, 5 prospective, and 6 retrospective studies involving 319 patients were included in the meta-analysis. A single-arm meta-analysis of the included studies showed a beneficial effect of the intervention in terms of pain relief outcomes like VAS score (p < 0.001), pain component of SF-36 (p = 0.003) while such improvement was not seen in functional outcome measures like ODI score (p = 0.071), the physical component of SF-36 (p = 0.130) with significant heterogeneity noted among the included studies. No structural improvement in magnetic resonance imaging was observed (p = 0.106). No additional procedure-related adverse events were noted in the included studies (p = 0.662). Conclusion: There is a paucity of high-quality studies to give conclusive evidence on the benefits of intradiscal PRP for lumbar disc disease. Although intradiscal PRP injection has shown some beneficial effect in controlling pain for lumbar disc disease, we could not find structural or functional improvement from the included studies. Hence, we recommend large double-blind double-arm randomized controlled studies to analyze the benefits of the intervention being analyzed.

Vertebral bone-marrow changes in degenerative lumbar disc disease. An MRI study of 74 patients with low back pain

1994 ◽  
Vol 76-B (5) ◽  
pp. 757-764 ◽  
Author(s):  
T Toyone ◽  
K Takahashi ◽  
H Kitahara ◽  
M Yamagata ◽  
M Murakami ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Low Back Pain ◽  
Back Pain ◽  
Lumbar Disc ◽  
Low Back ◽  
Disc Disease ◽  
Lumbar Disc Disease ◽  
Vertebral Bone ◽  
Vertebral Bone Marrow ◽  
Mri Study

scholarly journals Association between promoter -1607 polymorphism of MMP1 and Lumbar Disc Disease in Southern Chinese

2008 ◽  
Vol 9 (1) ◽  
Author(s):  
You-Qiang Song ◽  
Daniel WH Ho ◽  
Jaro Karppinen ◽  
Patrick YP Kao ◽  
Bao-Jian Fan ◽  
...  
Keyword(s):  
Lumbar Disc ◽  
Disc Disease ◽  
Lumbar Disc Disease ◽  
Southern Chinese

The Vertebral Canals in Lumbar Disc Disease

Spine ◽  
1984 ◽  
Vol 9 (4) ◽  
pp. 414-417 ◽  
Author(s):  
KEN WINSTON ◽  
CALVIN RUMBAUGH ◽  
VINCENT COLUCCI
Keyword(s):  
Lumbar Disc ◽  
Disc Disease ◽  
Lumbar Disc Disease

scholarly journals Retrospective study of effectiveness in transforminal nerve root block in lumbar disc disease

2021 ◽  
Vol 7 (1) ◽  
pp. 533-535
Author(s):  
Dr. Vishnu Vikraman Nair ◽  
Dr. Sarabjeet Singh Kohli ◽  
Dr. Nilesh Vikshwakarma ◽  
Dr. Shaival Chauhan
Keyword(s):  
Retrospective Study ◽  
Nerve Root ◽  
Lumbar Disc ◽  
Disc Disease ◽  
Lumbar Disc Disease ◽  
Nerve Root Block

scholarly journals Short-term clinical outcomes of 220 dogs with thoraco-lumbar disc disease treated by mini-hemilaminectomy

2020 ◽  
Vol 91 ◽  
Author(s):  
Ross C. Elliott ◽  
Chantel Moon ◽  
Gareth Zeiler ◽  
Remo Lobetti
Keyword(s):  
Clinical Outcomes ◽  
Lumbar Disc ◽  
Short Term ◽  
Disc Disease ◽  
Lumbar Disc Disease

Complications of chemonucleolysis for lumbar disc disease

Neurosurgery ◽  
1977 ◽  
Vol 1 (1) ◽  
pp. 2???5 ◽  
Author(s):  
C Watts
Keyword(s):  
Lumbar Disc ◽  
Disc Disease ◽  
Lumbar Disc Disease

scholarly journals Fusion of Interspinous Processes (H-graft): Methods for Unstable Lumbar Disc Disease.

1993 ◽  
Vol 42 (3) ◽  
pp. 1119-1122
Author(s):  
Nobuaki Tsunoda
Keyword(s):  
Lumbar Disc ◽  
Disc Disease ◽  
Lumbar Disc Disease

The Neurosurgical Approach to Lumbar Disc Disease

1971 ◽  
Vol 2 (2) ◽  
pp. 499-506
Author(s):  
Frederick A. Simeone
Keyword(s):  
Lumbar Disc ◽  
Disc Disease ◽  
Lumbar Disc Disease
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