Simultaneous GLC Determination of Methyl Salicylate and Menthol in a Topical Analgesic Formulation

1979 ◽  
Vol 68 (4) ◽  
pp. 506-508 ◽  
Author(s):  
Joseph P. Sapio ◽  
Krish Sethachutkul ◽  
Joseph E. Moody
Keyword(s):  
Methyl Salicylate ◽  
Topical Analgesic

Simultaneous GC determination of turpentine, camphor, menthol and methyl salicylate in a topical analgesic formulation (Dologex®)

2000 ◽  
Vol 52 (3-4) ◽  
pp. 245-248 ◽  
Author(s):  
E. González-Peñas ◽  
M. López-Alvarez ◽  
F. Martínez de Narvajas ◽  
A. Ursúa
Keyword(s):  
Methyl Salicylate ◽  
Topical Analgesic

Gas Chromatographic Determination of Phenolic Compounds in Drug Preparations: Collaborative Study

1972 ◽  
Vol 55 (3) ◽  
pp. 610-612 ◽  
Author(s):  
Carol C Douglas
Keyword(s):  
Phenolic Compounds ◽  
Methyl Salicylate ◽  
Chromatographic Method ◽  
Collaborative Study ◽  
Chromatographic Determination ◽  
The Other ◽  
Gas Chromatographic Method

Abstract A gas chromatographic method for the determination of phenol, methyl salicylate, menthol , and camphor in drug preparations was studied collaboratively by 9 laboratories. Mean recoveries were: phenol 98.2, 106.0, a n d 103.6%; methyl salicylate 103.9, 102.0, and 101.9%; menthol 102.9 and 100.9%; and camphor 101.9 and 100.9%. The method has been adopted as official first action for camphor-containing drugs. Additional study will be done to improve recoveries for the other 3 compounds.

Determination of Free Phenols in Methyl Salicylate

1940 ◽  
Vol 29 (3) ◽  
pp. 130-132
Author(s):  
R.W. Towne ◽  
R.M. Hitchens ◽  
M.S. McCauley
Keyword(s):  
Methyl Salicylate

Determination of methyl salicylate in black tea

1976 ◽  
Vol 65 (1) ◽  
pp. 11-15 ◽  
Author(s):  
K. O. Abraham ◽  
M. L. Shankaranarayana ◽  
B. Raghavan ◽  
C. P. Natarajan
Keyword(s):  
Methyl Salicylate ◽  
Black Tea

Rapid Colorimetric Method for the Determination of Methyl Salicylate in Medicated Oils

1966 ◽  
Vol 49 (4) ◽  
pp. 854-856
Author(s):  
M C Dutt
Keyword(s):  
Aqueous Solution ◽  
Ferric Chloride ◽  
Calibration Curve ◽  
Methyl Salicylate ◽  
Quantitative Estimation ◽  
Colorimetric Method ◽  
Synthetic Mixture ◽  
Excess Water ◽  
Ether Solution

Abstract The well-known reaction between methyl salicylate and ferric chloride has been successfully applied to the quantitative estimation of methyl salicylate in medicated oils. An aqueous solution of ferric chloride is added to an ether solution of medicated oil dissolved in excess water. After filtering, the absorbance of the filtrate is measured at 530 m/j, and the content of methyl salicylate is determined from a calibration curve. Methyl salicylate recoveries range from 92 to 97% for concentrations between 10 and 60% in a synthetic mixture. The method is simple and rapid, and compares favorably with Wilson’s method.

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