Label‐free detection of polysulfides and glycogen of Cyanidium caldarium using ultra‐multiplex coherent anti‐Stokes Raman scattering microspectroscopy

2021 ◽  
Author(s):  
Yuki Oka ◽  
Masaki Yoshida ◽  
Ayumi Minoda ◽  
Philippe Leproux ◽  
Makoto M. Watanabe ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Label Free ◽  
Cyanidium Caldarium ◽  
Label Free Detection ◽  
Anti Stokes

scholarly journals Wide-field Surface-Enhanced Coherent Anti-Stokes Raman Scattering Microscopy

2021 ◽  
Author(s):  
Cheng Zong ◽  
Ran Cheng ◽  
Fukai Chen ◽  
Peng Lin ◽  
Meng Zhang ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Large Scale ◽  
Time Lapse ◽  
Live Cells ◽  
Large Field ◽  
Wide Field ◽  
Label Free ◽  
Label Free Detection ◽  
Surface Enhanced ◽  
Anti Stokes

Surface-enhanced Raman scattering (SERS) spectroscopy has been used extensively to study biology, chemistry, and materials. However, a point-by-point SERS mapping is time-consuming, taking minutes to hours for large-scale imaging. Here, we report a wide-field surface-enhanced coherent anti-Stokes Raman scattering (WISE-CARS) microscopy for monitoring nanotags in live cells and label-free detection of metabolic molecules. The WISE-CARS microscope achieves an imaging speed as fast as 120 frames per second for a large field of view of 130 microns X 130 microns. By spectral focusing of femtosecond lasers, a hyperspectral WISE-CARS stack of 120 frames can be acquired with a spectral resolution of 10 cm-1, where over 1 million Raman spectra are parallelly recorded within 0.5 seconds. As applications, we demonstrate time-lapse, 3D WISE-CARS imaging of nanotags in live cells as well as label-free detection of adenine released from S. aureus.

scholarly journals Rapid and label-free detection of COVID-19 using coherent anti-Stokes Raman scattering microscopy

2020 ◽  
Vol 10 (4) ◽  
pp. 566-572
Author(s):  
Tanveer A. Tabish ◽  
Roger J. Narayan ◽  
Mohan Edirisinghe
Keyword(s):  
Raman Scattering ◽  
Label Free ◽  
Label Free Detection ◽  
Anti Stokes

Facile and Label-Free Detection of Lung Cancer Biomarker in Urine by Magnetically Assisted Surface-Enhanced Raman Scattering

2014 ◽  
Vol 6 (23) ◽  
pp. 20985-20993 ◽  
Author(s):  
Tianxi Yang ◽  
Xiaoyu Guo ◽  
Yiping Wu ◽  
Hui Wang ◽  
Shuyue Fu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Raman Scattering ◽  
Surface Enhanced Raman Scattering ◽  
Cancer Biomarker ◽  
Label Free ◽  
Label Free Detection ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Lung Cancer Biomarker

Label-Free Imaging of Adipogenesis by Coherent Anti-Stokes Raman Scattering Microscopy

2014 ◽  
pp. 189-201 ◽  
Author(s):  
Antti Isomäki ◽  
Tarvo Sillat ◽  
Mari Ainola ◽  
Mikko Liljeström ◽  
Yrjö T. Konttinen ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Label Free ◽  
Anti Stokes

scholarly journals Coherent anti-Stokes Raman scattering for label-free biomedical imaging

2013 ◽  
Vol 15 (9) ◽  
pp. 094006 ◽  
Author(s):  
Imran I Patel ◽  
Christian Steuwe ◽  
Stefanie Reichelt ◽  
Sumeet Mahajan
Keyword(s):  
Raman Scattering ◽  
Biomedical Imaging ◽  
Label Free ◽  
Anti Stokes

Surface-Enhanced Raman Scattering-Based Sensing In Vitro: Facile and Label-Free Detection of Apoptotic Cells at the Single-Cell Level

2013 ◽  
Vol 85 (5) ◽  
pp. 2809-2816 ◽  
Author(s):  
Xiangxu Jiang ◽  
Ziyun Jiang ◽  
Tingting Xu ◽  
Shao Su ◽  
Yiling Zhong ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Single Cell ◽  
Single Cell Level ◽  
Label Free ◽  
Cell Level ◽  
Label Free Detection ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Label-Free Imaging of Lipophilic Bioactive Molecules during Lipid Digestion by Multiplex Coherent Anti-Stokes Raman Scattering Microspectroscopy

2010 ◽  
Vol 132 (24) ◽  
pp. 8433-8439 ◽  
Author(s):  
James P. R. Day ◽  
Gianluca Rago ◽  
Katrin F. Domke ◽  
Krassimir P. Velikov ◽  
Mischa Bonn
Keyword(s):  
Raman Scattering ◽  
Bioactive Molecules ◽  
Label Free ◽  
Lipid Digestion ◽  
Anti Stokes

Label-free flow cytometry using multiplex coherent anti-Stokes Raman scattering (MCARS) for biological analysis

2011 ◽  
Author(s):  
Charles H. Camp ◽  
Siva Yegnanarayanan ◽  
Ali A. Eftekhar ◽  
Ali Adibi
Keyword(s):  
Flow Cytometry ◽  
Raman Scattering ◽  
Free Flow ◽  
Label Free ◽  
Biological Analysis ◽  
Anti Stokes

Label-free flow cytometry using multiplex coherent anti-Stokes Raman scattering (MCARS) for the analysis of biological specimens

2011 ◽  
Vol 36 (12) ◽  
pp. 2309 ◽  
Author(s):  
Charles H. Camp, Jr. ◽  
Siva Yegnanarayanan ◽  
Ali A. Eftekhar ◽  
Ali Adibi
Keyword(s):  
Flow Cytometry ◽  
Raman Scattering ◽  
Free Flow ◽  
Label Free ◽  
Anti Stokes
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