Sphincter‐saving surgery for ultra‐low rectal carcinoma initially indicated for abdominoperineal resection: Is it safe on a long‐term follow‐up?

2020 ◽  
Vol 123 (1) ◽  
pp. 299-310
Author(s):  
Philippe Rouanet ◽  
Michel Rivoire ◽  
Sophie Gourgou ◽  
Bernard Lelong ◽  
Eric Rullier ◽  
...  

2009 ◽  
Vol 136 (5) ◽  
pp. A-893
Author(s):  
Anjali S. Kumar ◽  
Amy W. Cheng ◽  
Elisabeth Garwood ◽  
Deirdre C. Kelleher ◽  
Abu Nasar ◽  
...  


2007 ◽  
Vol 6 (6) ◽  
pp. 436-441 ◽  
Author(s):  
Chadi Nabhan ◽  
Avanthi Ragam ◽  
Brian Samuels ◽  
Daniel T. Milton ◽  
Leela Prasad ◽  
...  


Author(s):  
A. Wolicki ◽  
P. Jäger ◽  
T. Deska ◽  
M. Senkal




2002 ◽  
Vol 6 (4) ◽  
pp. 260-261
Author(s):  
A Martling ◽  
T Holm ◽  
H Johansson ◽  
L.E Rutqvist ◽  
B Cedermark


2021 ◽  
Vol 14 (9) ◽  
pp. e244192
Author(s):  
Carlos Eduardo Costa Almeida ◽  
José Azevedo ◽  
Inês Botelho ◽  
Jaime Vilaça

Buschke-Löwenstein tumour (BLT) is rare and locally aggressive, and malignant transformation is a possibility. Because there is no consensus on the best treatment approach, the authors present a treatment algorithm based on several case reports. A 57-year-old male patient resorted to surgical consultation with a giant perianal cauliflower-like mass. A BLT was diagnosed. Due to the involvement of the anal sphincter, a wide local excision saving the rectum failed. Abdominoperineal resection was performed. Malignant transformation was diagnosed, and adjuvant radiotherapy was delivered. Clinical evolution was uneventful. Aggressive behaviour despite the absence of malignancy is the hallmark of BLT. The common presentation is an anal mass with a cauliflower-like appearance. Anal verrucous carcinoma and squamous cell carcinoma are the major differential diagnoses. BLT treatment is challenging. Surgery is the first-line treatment, raging from wide local excision to abdominoperineal resection. To improve outcomes, chemoradiation can be used in combination with surgery. Long-term follow-up is mandatory.





2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.



2001 ◽  
Vol 3 (1) ◽  
pp. 28-32 ◽  
Author(s):  
J. Tiainen ◽  
M. Matikainen ◽  
P. Aitola ◽  
K-M. Hiltunen ◽  
J. Mattila


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