Comparison of voice outcomes after trial and long-term vocal fold augmentation in vocal fold atrophy

2015 ◽  
Vol 125 (4) ◽  
pp. 934-940 ◽  
Author(s):  
VyVy N. Young ◽  
Jackie Gartner-Schmidt ◽  
Clark A. Rosen
Keyword(s):  
Vocal Fold ◽  
Vocal Fold Augmentation ◽  
Vocal Fold Atrophy

Long-term histological outcomes of injected autologous fat into human vocal folds after secondary laryngectomy

2005 ◽  
Vol 132 (5) ◽  
pp. 685-688 ◽  
Author(s):  
Hisanori Sasai ◽  
Yusuke Watanabe ◽  
Hiroshi Muta ◽  
Junichi Yoshida ◽  
Ibuki Hayashi ◽  
...  
Keyword(s):  
Vocal Fold ◽  
Vocal Folds ◽  
Vocal Fold Paralysis ◽  
Histological Evaluation ◽  
Fat Injection ◽  
Special Equipment ◽  
Autologous Fat ◽  
Vocal Fold Augmentation ◽  
Disposable Needle

OBJECTIVE: To histologically evaluate the long-term outcomes of autologous fat grafts after injection laryngoplasty in the human larynx. STUDY DESIGN AND SETTING: We injected liposuctioned fat for vocal fold augmentation in patients with vocal fold paralysis. We suctioned autologous fat from the low abdomen with an 18-G disposable needle and a 20-mL disposable syringe under negative pressure. This is different from the conventional liposuction technique and avoids the use of special equipment. In this article, we report the histological evaluation of 2 patients (patient 1: 12 months, patient 2: 41 months) who required total laryngectomy after autologous fat injection into the vocal folds. RESULTS: Histological examination revealed normal-appearing viable adipocytes with minimal inflammatory response in both patients. CONCLUSIONS: Our liposuctioned autologous fat injection histologically offered long-term improvement in patients with impaired glottal closure from vocal fold paralysis. (Otolaryngol Head Neck Surg 2005;132:685-688.)

Autologous replacement of the vocal fold: a new surgical approach for adduction-type spasmodic dysphonia

2005 ◽  
Vol 119 (3) ◽  
pp. 222-225 ◽  
Author(s):  
Koichi Tsunoda ◽  
Naomi Amagai ◽  
Kenji Kondou ◽  
Tom Baer ◽  
Kimitaka Kaga ◽  
...  
Keyword(s):  
Surgical Approach ◽  
Vocal Fold ◽  
Surgical Approaches ◽  
Spasmodic Dysphonia ◽  
Long Term Follow Up ◽  
New Type ◽  
Vocal Fold Atrophy ◽  
Glue Injection

Many surgical approaches have been developed for the treatment of adduction-type spasmodic dysphonia (SPD). We developed and performed a new type of surgical approach (autologous replacement of the vocal fold).Our new surgical technique increases the advantages and decreases the disadvantages of previous surgical procedures in three ways: (1) It has similar effects to the previous procedures in that it prevents contraction of the thyroarytenoid muscle. (2) It decreases vocal-fold tension, as in framework surgery. (3) It reduces glottal incompetence, as does fibrinogen-glue injection, but it is more suitable because it is autologous. Furthermore, it produces increases in the mass and volume of the vocal-fold body and is also safe because the replacement tissue is autologous.The short-term results appear encouraging in preventing spastic voice while also avoiding vocal-fold atrophy. Long-term follow up will be necessary to determine the actual efficacy. However, this is clearly a possible choice as a surgical approach for treating adduction-type SPD.

Development of a microporous annealed particle hydrogel for long‐term vocal fold augmentation

2019 ◽  
Vol 130 (10) ◽  
pp. 2432-2441 ◽  
Author(s):  
Lauren Pruett ◽  
Heather Koehn ◽  
Teresa Martz ◽  
Ian Churnin ◽  
Sergio Ferrante ◽  
...  
Keyword(s):  
Vocal Fold ◽  
Vocal Fold Augmentation

scholarly journals Vocal Fold Augmentation with Injectable Polycaprolactone Microspheres/Pluronic F127 Hydrogel: Long-Term In Vivo Study for the Treatment of Glottal Insufficiency

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e85512 ◽  
Author(s):  
Seong Keun Kwon ◽  
Hee-Bok Kim ◽  
Jae-Jun Song ◽  
Chang Gun Cho ◽  
Seok-Won Park ◽  
...  
Keyword(s):  
Vocal Fold ◽  
Pluronic F127 ◽  
In Vivo Study ◽  
Vocal Fold Augmentation ◽  
Glottal Insufficiency

Objective Voice Analysis after Autologous Fat Injection for Unilateral Vocal Fold Paralysis

2001 ◽  
Vol 110 (3) ◽  
pp. 229-235 ◽  
Author(s):  
Dana M. Hartl ◽  
Marc Riquet ◽  
Stéphane Hans ◽  
Ollivier Laccourreye ◽  
Jacqueline Vaissière ◽  
...  
Keyword(s):  
Vocal Fold ◽  
Vocal Fold Paralysis ◽  
Unilateral Vocal Fold Paralysis ◽  
Autologous Fat ◽  
Vocal Fold Augmentation ◽  
Average Spectrum ◽  
Normal Voice ◽  
Cepstral Peak Prominence ◽  
Vocal Fold Atrophy ◽  
Male Patients

This study was designed to objectively compare a patient's voice after onset of unilateral vocal fold paralysis (UVFP) to his or her own normal voice, and to compare the results after treatment by intrafold injection of autologous fat. Acoustic recordings were obtained for 2 male patients before thoracic surgery and after the onset of iatrogenic left UVFP. Vocal fold augmentation was performed 10 days after UVFP. The acoustic recordings were repeated within 3 days and at 1 month. The phonation quotient, pitch perturbation quotient, amplitude perturbation quotient, harmonics-to-noise ratio, cepstral peak prominence, and long-term average spectrum were analyzed. All parameters improved after treatment, with a return to preparalytic values for most. During the first month, some deterioration was noted. This is the first study comparing a subject's own normal voice to his or her voice after vocal fold augmentation. We recommend overinjection of fat if vocal fold atrophy is expected.

Long-term results of calcium hydroxylapatite for vocal fold augmentation

2011 ◽  
Vol 121 (2) ◽  
pp. 313-319 ◽  
Author(s):  
Thomas L. Carroll ◽  
Clark A. Rosen
Keyword(s):  
Vocal Fold ◽  
Long Term Results ◽  
Calcium Hydroxylapatite ◽  
Vocal Fold Augmentation

Vocal fold augmentation by autologous fat injection with lipostructure procedure

2005 ◽  
Vol 132 (2) ◽  
pp. 239-243 ◽  
Author(s):  
Giovanna Cantarella ◽  
Riccardo F. Mazzola ◽  
Elena Domenichini ◽  
Flavio Arnone ◽  
Barbara Maraschi
Keyword(s):  
Vocal Fold ◽  
Cell Layer ◽  
Voice Quality ◽  
Voice Rehabilitation ◽  
Fat Cell ◽  
Maximum Phonation Time ◽  
Vocal Fold Augmentation ◽  
Self Assessments ◽  
The Ideal

BACKGROUND: Fat is theoretically the ideal implant for vocal fold augmentation because it is soft, easily available and biocompatible. However, reabsorption is a frequent cause of long-term failure. OBJECTIVE: We prospectively tested Coleman's “li-postructure” technique used for facial recontouring in the treatment of glottic incompetence. STUDY DESIGN AND SETTING: Fourteen patients (aged 18–74 years, mean 48) with breathy dysphonia secondary to laryngeal hemiplegia (7) or anatomical defects (7) underwent vocal fold lipoinjection. Fat harvested by liposuction was centrifuged, and the fat cell layer injected into the vocalis muscle. The patients underwent pre- and postoperative videolaryngostroboscopy, maximum phonation time (MPT) measurements, GRBAS perceptual evaluations, and Voice Handicap Index (VHI) self-assessments. RESULTS: Voice quality improved soon after surgery and remained stable over 3–26 months (mean 10.6), being confirmed by the GRBAS, MPT and VHI evaluations ( P < 0.005). The results were best in the seven patients with paralytic dysphonia. CONCLUSION: Lipostructure is a valuable technique for voice rehabilitation in glottic incompetence.

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