scholarly journals A prospective cross-over study comparing the effect of mycophenolate versus azathioprine on allograft function and viral load in liver transplant recipients with recurrent chronic HCV infection

2004 ◽  
Vol 10 (1) ◽  
pp. 52-57 ◽  
Author(s):  
Amany Zekry ◽  
Margret Gleeson ◽  
Seren Guney ◽  
Geoffrey W. McCaughan
Keyword(s):  
Viral Load ◽  
Liver Transplant ◽  
Hcv Infection ◽  
Transplant Recipients ◽  
Allograft Function ◽  
Chronic Hcv Infection ◽  
Chronic Hcv ◽  
Liver Transplant Recipients

scholarly journals Incidence and Predictors of Advanced Liver Fibrosis by a Validated Serum Biomarker in Liver Transplant Recipients

2017 ◽  
Vol 2017 ◽  
pp. 1-8
Author(s):  
Mamatha Bhat ◽  
Kathleen C. Rollet-Kurhajec ◽  
Aparna Bhat ◽  
Amanda Farag ◽  
Marc Deschenes ◽  
...  
Keyword(s):  
Liver Fibrosis ◽  
Liver Transplant ◽  
Hcv Infection ◽  
Serum Biomarker ◽  
Advanced Fibrosis ◽  
Advanced Liver Fibrosis ◽  
Chronic Hcv Infection ◽  
Chronic Hcv ◽  
Liver Transplant Recipients

Background and Aims. Serum fibrosis biomarkers have shown good accuracy in the liver transplant (LT) population. We employed a simple serum biomarker to elucidate incidence and predictors of advanced fibrosis after LT over a long follow-up period.Methods. We included 440 consecutive patients who underwent LT between 1991 and 2013. Advanced liver fibrosis was defined as FIB-4 > 3.25 beyond 12 months after LT.Results. Over 2030.5 person-years (PY) of follow-up, 189 (43%) developed FIB-4 > 3.25, accounting for an incidence of 9.3/100 PY (95% confidence interval [CI], 8.1–10.7). Advanced fibrosis was predicted by chronic HCV infection (adjusted hazard ratio (aHR) = 3.96, 95% CI 2.92–5.36,p< 0.001), hypoalbuminemia (aHR = 2.31, 95% CI 1.72–3.09;p< 0.001), and hyponatremia (aHR = 1.48, 95% CI 1.09–2.01;p= 0.01). LT recipients with more than 1 predictor had a higher incidence of advanced fibrosis, the highest being when all 3 predictors coexisted (log-rank:p< 0.001).Conclusions. Chronic HCV infection, hypoalbuminemia, and hyponatremia predict progression to advanced liver fibrosis following LT. Patients with these risk factors should be serially monitored using noninvasive fibrosis biomarkers and prioritized for interventions.

Early steatosis and past HBV infection predict fibrosis progression in liver transplant recipients with recurrent HCV infection

2000 ◽  
Vol 118 (4) ◽  
pp. A995
Author(s):  
Mario Angelico ◽  
Giampiero Palmieri ◽  
Daniele Di Paolo ◽  
Elena Torri ◽  
Giuseppe Iaria ◽  
...  
Keyword(s):  
Liver Transplant ◽  
Hcv Infection ◽  
Hbv Infection ◽  
Transplant Recipients ◽  
Fibrosis Progression ◽  
Liver Transplant Recipients

scholarly journals Successful sofosbuvir-based therapy in HIV/HCV coinfected liver transplant recipients with recurrent HCV infection

AIDS ◽  
2015 ◽  
pp. 1 ◽  
Author(s):  
Jennifer L. Grant ◽  
Claudia Hawkins ◽  
Hannah Brooks ◽  
Frank J. Palella ◽  
Sean W.P. Koppe ◽  
...  
Keyword(s):  
Liver Transplant ◽  
Hcv Infection ◽  
Transplant Recipients ◽  
Liver Transplant Recipients

scholarly journals Increased killer B cells in chronic HCV infection may lead to autoimmunity and increased viral load

2018 ◽  
Vol 193 (2) ◽  
pp. 183-193 ◽  
Author(s):  
N. Eiza ◽  
E. Zuckerman ◽  
M. Carlebach ◽  
T. Rainis ◽  
Y. Goldberg ◽  
...  
Keyword(s):  
Viral Load ◽  
B Cells ◽  
Hcv Infection ◽  
Chronic Hcv Infection ◽  
Chronic Hcv

Treatment of HCV infection in liver transplant recipients with ledipasvir and sofosbuvir without ribavirin

2017 ◽  
Vol 45 (11) ◽  
pp. 1427-1432 ◽  
Author(s):  
A. A. Pillai ◽  
R. Maheshwari ◽  
R. Vora ◽  
J. P. Norvell ◽  
R. Ford ◽  
...  
Keyword(s):  
Liver Transplant ◽  
Hcv Infection ◽  
Transplant Recipients ◽  
Liver Transplant Recipients

Preemptive therapy for cytomegalovirus based on real-time measurement of viral load in liver transplant recipients

2010 ◽  
Vol 23 (4) ◽  
pp. 166-169 ◽  
Author(s):  
Hsin-Yun Sun ◽  
Thomas V. Cacciarelli ◽  
Marilyn M. Wagener ◽  
Nina Singh
Keyword(s):  
Viral Load ◽  
Liver Transplant ◽  
Real Time ◽  
Time Measurement ◽  
Preemptive Therapy ◽  
Transplant Recipients ◽  
Real Time Measurement ◽  
Liver Transplant Recipients

Use of cytokine polymorphisms and Epstein-Barr virus viral load to predict development of post-transplant lymphoproliferative disorder in paediatric liver transplant recipients

2006 ◽  
Vol 20 (3) ◽  
pp. 389-393 ◽  
Author(s):  
Timothy C. Lee ◽  
Barbara Savoldo ◽  
Neal R. Barshes ◽  
Cliona M. Rooney ◽  
Helen E. Heslop ◽  
...  
Keyword(s):  
Viral Load ◽  
Liver Transplant ◽  
Lymphoproliferative Disorder ◽  
Epstein Barr Virus ◽  
Transplant Recipients ◽  
Post Transplant ◽  
Barr Virus ◽  
Epstein Barr ◽  
Liver Transplant Recipients

135 Staging of hepatic fibrosis by liver elastometry (fibroscan) in recurrent HCV infection in liver transplant recipients

2006 ◽  
Vol 44 ◽  
pp. S59 ◽  
Author(s):  
F. Corradi ◽  
F. Piscaglia ◽  
R. Tame ◽  
A. Colecchia ◽  
P. Andreone ◽  
...  
Keyword(s):  
Liver Transplant ◽  
Hepatic Fibrosis ◽  
Hcv Infection ◽  
Transplant Recipients ◽  
Liver Transplant Recipients

Risk for Immune-Mediated Graft Dysfunction in Liver Transplant Recipients With Recurrent HCV Infection Treated With Pegylated Interferon

2012 ◽  
Vol 142 (5) ◽  
pp. 1132-1139.e1 ◽  
Author(s):  
Josh Levitsky ◽  
Maria Isabel Fiel ◽  
John P. Norvell ◽  
Edward Wang ◽  
Kymberly D. Watt ◽  
...  
Keyword(s):  
Liver Transplant ◽  
Pegylated Interferon ◽  
Hcv Infection ◽  
Transplant Recipients ◽  
Graft Dysfunction ◽  
Immune Mediated ◽  
Liver Transplant Recipients
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