MicroRNAs 155‐5p, 122‐5p, and 181a‐5p Identify Patients With Graft Dysfunction Due to T Cell–Mediated Rejection After Liver Transplantation

2020 ◽  
Vol 26 (10) ◽  
pp. 1275-1286 ◽  
Author(s):  
Pablo Ruiz ◽  
Olga Millán ◽  
Jose Ríos ◽  
Alba Díaz ◽  
Lydia Sastre ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
T Cell ◽  
Graft Dysfunction

SAT-440-Molecular fingerprint of T cell-mediated and antibody-mediated rejection after human liver transplantation

2019 ◽  
Vol 70 (1) ◽  
pp. e830
Author(s):  
Anne Höfer ◽  
Danny Jonigk ◽  
Björn Hartleben ◽  
Robert Geffers ◽  
Murielle Verboom ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
T Cell ◽  
Human Liver ◽  
Molecular Fingerprint ◽  
Antibody Mediated Rejection

scholarly journals Early graft calcification without graft dysfunction after living donor liver transplantation: two case reports

2021 ◽  
Vol 14 (5) ◽  
pp. 1491-1495
Author(s):  
Peilin Li ◽  
Masaaki Hidaka ◽  
Yu Huang ◽  
Takanobu Hara ◽  
Kantoku Nagakawa ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Hepatic Artery ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Liver Graft ◽  
Graft Dysfunction ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
First Case ◽  
Post Operation

AbstractGraft calcification after liver transplantation (LT) has seldom been reported, but almost of all previously reported cases have been attributed to graft dysfunction. We herein report two cases of graft calcification without liver dysfunction after living donor liver transplantation (LDLT). Two patients who underwent LDLT were found to have graft calcification in the early postoperative period (< 1 month). Calcification in the first case was found at the cut edge of the liver at post-operative day (POD) 10, showing a time-dependent increase in calcification severity. The second patient underwent hepatic artery re-anastomosis due to hepatic artery thrombosis on POD4 and received balloon-occluded retrograde transvenous obliteration of the splenic kidney shunt due to decreased portal vein blood flow on POD6. She was found to have diffuse hepatic calcification in the distant hepatic artery area at 1-month post-operation followed by gradual graft calcification at the resection margin at 6-month post-operation. Neither case showed post-operative graft dysfunction. Calcification of the liver graft after LDLT is likely rare, and graft calcification does not seem to affect the short-term liver function in LDLT cases. We recommend strictly controlling the warm/cold ischemia time and reducing the physical damage to the donor specimen as well as monitoring for early calcification by computed tomography.

scholarly journals Early Graft Dysfunction after Live Donor Liver Transplantation: It’s time to redefine?

2021 ◽  
Author(s):  
Viniyendra Pamecha ◽  
Bramhadatta Pattnaik ◽  
Piyush Kumar Sinha ◽  
Nilesh Sadashiv Patil ◽  
Shridhar Vasantrao Sasturkar ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Live Donor Liver Transplantation ◽  
Live Donor ◽  
Graft Dysfunction ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Live Donor Liver ◽  
Early Graft ◽  
Early Graft Dysfunction

scholarly journals Liver transplantation in Jehovah's Witnesses: a case series

1969 ◽  
Vol 48 (2) ◽  
pp. 85-90
Author(s):  
Fredy Ariza ◽  
Daniel Arboleda-Palacios ◽  
Sebastian Rosales Hooker-Herrera ◽  
Eliana Manzi-Tarapués ◽  
Luis Armando Caicedo-Rusca
Keyword(s):  
Liver Transplantation ◽  
Cell Mass ◽  
Case Series ◽  
Graft Dysfunction ◽  
Post Transplantation ◽  
Jehovah’S Witnesses ◽  
Intraoperative Bleeding ◽  
Jehovah's Witnesses ◽  
End Stage ◽  
To Receive

Introduction: Orthotopic liver transplantation (OLT) is a procedure characterized by high bleeding rates and a significant likelihood of exposure to blood products. Objectives: This case series shows the experience at a referral center for Jehovah's Witnesses (JW) with end-stage liver disease, undergoing OLT. Materials and methods: A search was conducted in our database of JW undergoing OLT between July 2007 and August 2012. The information about their pre-operative condition and progress up to 30 days post-transplantation. Results: Four subjects were identified (3F/1M) with an average age of 42 years (range 22-55). All of them received a multidisciplinary management which included pre-operative optimization of red cell mass, antifibrinolytic prophylaxis, and cell salvage (mean volume of 344mL [range 113-520]). The average intraoperative bleeding volume was of 625mL (range 300-1000). One of the patients presented with a primary graft dysfunction and died, while the rest had a normal postoperative course. Conclusion: It is possible to offer OLT to patients who refuse to receive allogeneic blood transfusions, through a comprehensive approach that includes perioperative hematologic optimization and the use of blood conservation measures, without a significant impact on the outcomes.

Impact of Primary Graft Dysfunction on Allograft T Cell Chimerism Following Lung Transplantation

2018 ◽  
Vol 37 (4) ◽  
pp. S82
Author(s):  
M.E. Snyder ◽  
T. Connors ◽  
L. Benvenuto ◽  
L. Shah ◽  
H. Robbins ◽  
...  
Keyword(s):  
T Cell ◽  
Lung Transplantation ◽  
Primary Graft Dysfunction ◽  
Graft Dysfunction

scholarly journals Postvaccination graft dysfunction/aplastic anemia relapse with massive clonal expansion of autologous CD8+ lymphocytes

2020 ◽  
Vol 4 (7) ◽  
pp. 1378-1382
Author(s):  
Caitlin Ritz ◽  
Wenzhao Meng ◽  
Natasha L. Stanley ◽  
Miren L. Baroja ◽  
Chong Xu ◽  
...  
Keyword(s):  
Bone Marrow ◽  
T Cell ◽  
T Lymphocytes ◽  
Aplastic Anemia ◽  
Clonal Expansion ◽  
Graft Dysfunction ◽  
Bone Marrow Aplasia ◽  
Key Points

Key Points Acquired aplastic anemia is a T-cell–mediated autoimmune bone marrow aplasia, without a known etiologic trigger. Clonal expansion of CD8+ effector T lymphocytes can occur following vaccination and accompany graft dysfunction or aplastic anemia relapse.

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