Segmented Polyurethanes for Medical Applications: Synthesis, Characterization andin vitro Enzymatic Degradation Studies

2001 ◽  
Vol 169 (1) ◽  
pp. 261-272 ◽  
Author(s):  
Gianluca Ciardelli ◽  
Alfonsina Rechichi ◽  
Piero Cerrai ◽  
Mario Tricoli ◽  
Niccoletta Barbani ◽  
...  
Keyword(s):  
Enzymatic Degradation ◽  
Medical Applications ◽  
Segmented Polyurethanes ◽  
Degradation Studies

Hydrolytic and enzymatic degradation studies of aliphatic 10-undecenoic acid-based polyesters

2018 ◽  
Vol 155 ◽  
pp. 84-94 ◽  
Author(s):  
Carmen Valverde ◽  
Gerard Lligadas ◽  
Juan C. Ronda ◽  
Marina Galià ◽  
Virginia Cádiz
Keyword(s):  
Enzymatic Degradation ◽  
Degradation Studies ◽  
Undecenoic Acid

Degradation studies on segmented polyurethanes prepared with HMDI, PCL and different chain extenders

2010 ◽  
Vol 6 (6) ◽  
pp. 2035-2044 ◽  
Author(s):  
L.H. Chan-Chan ◽  
R. Solis-Correa ◽  
R.F. Vargas-Coronado ◽  
J.M. Cervantes-Uc ◽  
J.V. Cauich-Rodríguez ◽  
...  
Keyword(s):  
Chain Extenders ◽  
Segmented Polyurethanes ◽  
Degradation Studies

Biological properties and enzymatic degradation studies of clindamycin-loaded PLA/HAp microspheres prepared from crocodile bones

2017 ◽  
Vol 74 (12) ◽  
pp. 5181-5194
Author(s):  
Juntima Pradid ◽  
Wirunya Keawwatana ◽  
Upsorn Boonyang ◽  
Siree Tangbunsuk
Keyword(s):  
Enzymatic Degradation ◽  
Biological Properties ◽  
Degradation Studies

Biocompatibility and enzymatic degradation studies on sulphated hyaluronic acid derivatives

Biomaterials ◽  
1997 ◽  
Vol 18 (21) ◽  
pp. 1411-1415 ◽  
Author(s):  
Giovanni Abatangelo ◽  
Rolando Barbucci ◽  
Paola Brun ◽  
Stefania Lamponi
Keyword(s):  
Hyaluronic Acid ◽  
Enzymatic Degradation ◽  
Degradation Studies

scholarly journals Enzymatic degradation of biofilm by metalloprotease from Microbacterium sp. SKS10

2019 ◽  
Author(s):  
Sandeep Kaur Saggu ◽  
Gopaljee Jha ◽  
Prakash Chandra Mishra
Keyword(s):  
Enzymatic Degradation ◽  
Enzyme Concentration ◽  
Effective Concentration ◽  
Carcinoma Cells ◽  
Toxic Chemicals ◽  
Sustainable Chemistry ◽  
Medical Applications ◽  
Purification And Characterization ◽  
Human Epidermoid Carcinoma

AbstractEnzymes have replaced or decreased usage of toxic chemicals for industrial and medical applications leading towards sustainable chemistry. In this study, we report purification and characterization of a biofilm degrading protease secreted by Microbacterium sp. SKS10. The protease was identified as a metalloprotease, Peptidase M16 using mass spectrometry. It showed optimum activity at 60 °C, pH 12 and retained its activity in the presence of various salts and organic solvents. The enzyme was able to degrade biofilms efficiently at enzyme concentration lower than other known enzymes such as papain, trypsin and □-amylase. The presence of this protease increased the accessibility of antibiotics inside the biofilm, and was found to be non-cytotoxic towards human epidermoid carcinoma cells (A431) at the effective concentration for biofilm degradation. Thus, this protease may serve as an effective tool for management of biofilms.

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