Radiobiological comparison between Cobalt‐60 and Iridium‐192 high‐dose‐rate brachytherapy sources: Part I—cervical cancer

2021 ◽  
Author(s):  
Mahdieh Dayyani ◽  
Elie Hoseinian‐Azghadi ◽  
Hashem Miri‐Hakimabad ◽  
Laleh Rafat‐Motavalli ◽  
Sara Abdollahi ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Dose Rate ◽  
High Dose Rate ◽  
High Dose ◽  
High Dose Rate Brachytherapy ◽  
Iridium 192

scholarly journals High Dose Rate Brachytherapy in the Treatment of Cervical Cancer: Preliminary Experience with Cobalt 60 Radionuclide Source—A Prospective Study

2010 ◽  
Vol 4 ◽  
pp. CMO.S5269 ◽  
Author(s):  
Atara Ntekim ◽  
Adeniyi Adenipekun ◽  
Bidemi Akinlade ◽  
Oladapo Campbell
Keyword(s):  
Cervical Cancer ◽  
Dose Rate ◽  
External Beam Radiotherapy ◽  
High Dose Rate ◽  
High Dose ◽  
High Dose Rate Brachytherapy ◽  
Low Resource Settings ◽  
Low Resource ◽  
Genitourinary Toxicity ◽  
Iridium 192

Iridium-192 is widely used for high-dose rate brachytherapy. Co-60 source with similar geometric and dosimetric properties are now available. It has a longer half life but higher energy than Iridium-192. If Co-60 source can produce similar results, it will be more economical for low resource settings. Objective To evaluate the acute gastrointestinal and genitourinary toxicity associated with Co-60 source in the brachytherapy of cervical cancer. Methods Seventy patients with cervical cancer received 45 Gy in 22 fractions of pelvic external beam radiotherapy and 19.5 Gy in 3 fractions of HDR with Co-60 source using tandem and ring applicators with 6 courses of cisplatin 50 mg/m2 and 5 fluorouracil 1000 mg/m2 every 3 weeks Toxicity was scored using NCI-CTC version 4.0. Results The median total BED (Gy10) for tumor was 86.2 (84.4–88.8) while that for rectum (BED Gy3) was 124.4 (120–133). Two patients (3%) had grade 3 gastrointestinal toxicity while all others had ≤grade 2 toxicity and this is comparable with previous results. Conclusion Co-60 as HDR brachytherapy source is tolerable and is economical for low resource settings.

Inverse Planning for CT-Based High-Dose-Rate Brachytherapy of Cervical Cancer

Brachytherapy ◽  
2010 ◽  
Vol 9 ◽  
pp. S88-S89
Author(s):  
Junsheng Cao ◽  
Haisong Liu ◽  
Pramila Rani Anne ◽  
Laura Doyle ◽  
Kaiguo Yan ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Dose Rate ◽  
High Dose Rate ◽  
High Dose ◽  
High Dose Rate Brachytherapy ◽  
Inverse Planning

scholarly journals Comparing efficacy of high-dose rate brachytherapy versus helical tomotherapy in the treatment of cervical cancer

2020 ◽  
Vol 31 (4) ◽  
Author(s):  
Seongmin Kim ◽  
Sanghoon Lee ◽  
Jin Hwa Hong ◽  
Young Je Park ◽  
Jae Yun Song ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Dose Rate ◽  
Helical Tomotherapy ◽  
High Dose Rate ◽  
High Dose ◽  
High Dose Rate Brachytherapy

Intraoperative and percutaneous iridium-192 high-dose-rate brachytherapy for previously irradiated lesions of the spine

Brachytherapy ◽  
2013 ◽  
Vol 12 (5) ◽  
pp. 449-456 ◽  
Author(s):  
Michael R. Folkert ◽  
Mark H. Bilsky ◽  
Gil'ad N. Cohen ◽  
Marco Zaider ◽  
Eric Lis ◽  
...  
Keyword(s):  
Dose Rate ◽  
High Dose Rate ◽  
High Dose ◽  
High Dose Rate Brachytherapy ◽  
Iridium 192

Inverse Planned High-Dose-Rate Brachytherapy for Locoregionally Advanced Cervical Cancer: 4-Year Outcomes

2015 ◽  
Vol 92 (5) ◽  
pp. 1093-1100 ◽  
Author(s):  
Christopher L. Tinkle ◽  
Vivian Weinberg ◽  
Lee-May Chen ◽  
Ramey Littell ◽  
J. Adam M. Cunha ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Dose Rate ◽  
High Dose Rate ◽  
High Dose ◽  
Advanced Cervical Cancer ◽  
High Dose Rate Brachytherapy
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