scholarly journals Implementation and experimental validation of a robust hybrid direct aperture optimization approach for mixed‐beam radiotherapy

2021 ◽  
Author(s):  
Emily Heath ◽  
Silvan Mueller ◽  
Gian Guyer ◽  
Alisha Duetschler ◽  
Olgun Elicin ◽  
...  
Author(s):  
Pulkit Shamshery ◽  
Amos G. Winter

This work discusses the modeling and optimization of a drip irrigation emitter for reducing activation pressure. Our model formulation focuses on analytically characterizing fluid-structure interactions in an existing 8 liters per hour (lph) pressure-compensating online emitter. A preliminary experimental validation of the resulting model was performed for three different emitter architectures. This model was used as a basis for a genetic algorithm-based optimization algorithm that focused on minimizing activation pressure. The design variables considered in our formulation include, geometric features of the emitter architecture, and practical constraints from manufacturing. We applied our optimization approach to four emitters (with flow rates of 4, 6, 7 and 8.2 lph) and were able to lower activation pressure by more than half in each case. The optimization results for all four emitters were experimentally validated in lab-studies. We performed a more exhaustive validation study for the 8.2 lph emitter with an emitter manufacturer. Results from these experiments (which followed ISO standards) showed that the optimized 8.2 lph emitter had a 75% lower activation pressure when compared to the original emitter design.


1995 ◽  
Author(s):  
Mark Sensmeier ◽  
Pradeep Sensharma ◽  
Raphael Haftka ◽  
O Griffin, r ◽  
Layne Watson

2020 ◽  
Vol 54 (6) ◽  
pp. 1703-1722 ◽  
Author(s):  
Narges Soltani ◽  
Sebastián Lozano

In this paper, a new interactive multiobjective target setting approach based on lexicographic directional distance function (DDF) method is proposed. Lexicographic DDF computes efficient targets along a specified directional vector. The interactive multiobjective optimization approach consists in several iteration cycles in each of which the Decision Making Unit (DMU) is presented a fixed number of efficient targets computed corresponding to different directional vectors. If the DMU finds one of them promising, the directional vectors tried in the next iteration are generated close to the promising one, thus focusing the exploration of the efficient frontier on the promising area. In any iteration the DMU may choose to finish the exploration of the current region and restart the process to probe a new region. The interactive process ends when the DMU finds its most preferred solution (MPS).


2015 ◽  
Vol 53 (01) ◽  
Author(s):  
L Spomer ◽  
CGW Gertzen ◽  
D Häussinger ◽  
H Gohlke ◽  
V Keitel

2016 ◽  
Vol 18 (1) ◽  
pp. 114
Author(s):  
She Wei ◽  
Huang Huang ◽  
Guan Chunyun ◽  
Chen Fu ◽  
Chen Guanghui

2018 ◽  
Vol 138 (8) ◽  
pp. 651-658 ◽  
Author(s):  
Keisuke Shirasaki ◽  
Naotaka Okada ◽  
Kenichiro Sano ◽  
Hideki Iwatsuki

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