1H NMR study of cyclo-L-Thr-L-Thr and cyclo-L-Thr-L-His conformations

1974 ◽  
Vol 6 (6) ◽  
pp. 358-359 ◽  
Author(s):  
Marius Ptak ◽  
Annie Heitz
Keyword(s):  
1H Nmr ◽  
Nmr Study

1H-NMR study of Mott insulator κ -(ET)2Cu2(CN)3with isotropic triangular lattice

2004 ◽  
Vol 114 ◽  
pp. 377-378 ◽  
Author(s):  
Y. Shimizu ◽  
K. Miyagawa ◽  
K. Oda ◽  
K. Kanoda ◽  
M. Maesato ◽  
...  
Keyword(s):  
1H Nmr ◽  
Triangular Lattice ◽  
Mott Insulator ◽  
Nmr Study

A 15N, 13C, and 1H NMR study of reaction products from arylguanidines and chloroformate esters

1991 ◽  
Vol 56 (7) ◽  
pp. 1505-1511 ◽  
Author(s):  
Antonín Lyčka ◽  
Karel Palát
Keyword(s):  
1H Nmr ◽  
Nmr Spectra ◽  
Reaction Products ◽  
H Nmr ◽  
Nmr Study

The 15N, 13C, and 1H NMR spectra of the reaction products from arylguanidines with two mols of chloroformate esters have been measured. With application of the corresponding 15N isotopomer it has been proved that the reaction products have the structures IIIa-IIIc.

scholarly journals 1H NMR study of [d(GCGATCGC)]2 and its interaction with minor groove binding 4',6-diamidino-2-phenylindole.

1993 ◽  
Vol 268 (6) ◽  
pp. 3944-3951
Author(s):  
E. Trotta ◽  
E. D'Ambrosio ◽  
N. Del Grosso ◽  
G. Ravagnan ◽  
M. Cirilli ◽  
...  
Keyword(s):  
1H Nmr ◽  
Minor Groove ◽  
Minor Groove Binding ◽  
Groove Binding ◽  
Nmr Study

1H NMR study of dodecanuclear polyoxovanadate cluster {V12}

2004 ◽  
Vol 272-276 ◽  
pp. E759-E761 ◽  
Author(s):  
B.J Suh ◽  
D Procissi ◽  
P Kögerler ◽  
E Micotti ◽  
A Lascialfari ◽  
...  
Keyword(s):  
1H Nmr ◽  
Nmr Study

scholarly journals Response of Cisplatin Resistant Skov-3 Cells to [Pt(O,O′-Acac)(γ-Acac)(DMS)] Treatment Revealed by a Metabolomic 1H-NMR Study

Molecules ◽  
2018 ◽  
Vol 23 (9) ◽  
pp. 2301 ◽  
Author(s):  
Federica De Castro ◽  
Michele Benedetti ◽  
Giovanna Antonaci ◽  
Laura Del Coco ◽  
Sandra De Pascali ◽  
...  
Keyword(s):  
Ovarian Carcinoma ◽  
1H Nmr ◽  
Mechanism Of Action ◽  
Culture Media ◽  
Epithelial Ovarian Carcinoma ◽  
Multivariate Statistical ◽  
Nmr Study ◽  
First Time

The novel [Pt(O,O′-acac)(γ-acac)(DMS)], Ptac2S, Pt(II) complex has recently gained increasing attention as a potential anticancer agent for its pharmacological activity shown in different tumor cell lines, studied both in vitro and in vivo. The mechanism of action of Ptac2S, operating on non-genomic targets, is known to be very different from that of cis-[PtCl2(NH3)2], cisplatin, targeting nucleic acids. In this work, we evaluated the cytotoxicity of Ptac2S on the cisplatin resistant Epithelial Ovarian Carcinoma (EOC), SKOV-3 cells, by the MTT assay. A 1H-NMR metabolomic approach coupled with multivariate statistical analysis was used for the first time for Ptac2S to figure out the biological mechanisms of action of the complex. The metabolic variations of intracellular metabolites and the composition of the corresponding extracellular culture media were compared to those of cisplatin (cells were treated at the IC50 doses of both drugs). The reported comparative metabolomic analysis revealed a very different metabolic profile between Ptac2S and cisplatin treated samples, thus confirming the different mechanism of action of Ptac2S also in the Epithelial Ovarian Carcinoma (EOC), SKOV-3 cells line. In particular, higher levels of pyruvate were observed in Ptac2S treated, with respect to cisplatin treated, cells (in both aqueous and culture media). In addition, a very different lipid expression resulted after the exposure to the two drugs (Ptac2S and cisplatin). These results suggest a possible explanation for the Ptac2S ability to circumvent cisplatin resistance in SKOV-3 cells.

1H NMR study of monocrotaline and its metabolites in human blood

2011 ◽  
Vol 49 (11) ◽  
pp. 2793-2799 ◽  
Author(s):  
Yi-Cheng Yang ◽  
John Crowder ◽  
Nicholas J. Wardle ◽  
Li Yang ◽  
Kenneth N. White ◽  
...  
Keyword(s):  
1H Nmr ◽  
Human Blood ◽  
Nmr Study

1H NMR Study of Protonation and Mg(II) Coordination of AMP, ADP, and ATP at 25, 50, and 70 °C

1996 ◽  
Vol 100 (22) ◽  
pp. 9556-9560 ◽  
Author(s):  
Peiming Wang ◽  
Reed M. Izatt ◽  
John L. Oscarson ◽  
Sue E. Gillespie
Keyword(s):  
1H Nmr ◽  
Nmr Study
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