Adipose‐derived stem cells delay muscle atrophy after peripheral nerve injury in the rodent model

2019 ◽  
Vol 59 (5) ◽  
pp. 603-610 ◽  
Author(s):  
Benjamin K. Schilling ◽  
M. Asher Schusterman ◽  
Deok‐Yeol Kim ◽  
Alexander J. Repko ◽  
Katarina C. Klett ◽  
...  
2019 ◽  
Vol 26 (2) ◽  
pp. 189-196 ◽  
Author(s):  
Cai‐Yue Liu ◽  
Gang Yin ◽  
Yi‐Dan Sun ◽  
Yao‐Fa Lin ◽  
Zheng Xie ◽  
...  

2014 ◽  
Vol 187 (1) ◽  
pp. 350-358 ◽  
Author(s):  
Jill E. Shea ◽  
Jared W. Garlick ◽  
Mohamed E. Salama ◽  
Shaun D. Mendenhall ◽  
Linh A. Moran ◽  
...  

2020 ◽  
Vol 15 (10) ◽  
pp. 2209-2228
Author(s):  
Amir Dehdashtian ◽  
Jarred V Bratley ◽  
Shelby R Svientek ◽  
Theodore A Kung ◽  
Tariq M Awan ◽  
...  

Despite recent advances in microsurgical techniques, functional recovery following peripheral nerve injury remains slow and inadequate. Poor peripheral nerve regeneration not only leaves patients with significant impairments, but also commonly leads to the development of debilitating neuropathic pain. Recent research has demonstrated the potential therapeutic benefits of adipose-derived stem cells, to enhance nerve regeneration. However, clinical translation remains limited due to the current regulatory burdens of the US FDA. A reliable and immediately translatable alternative is autologous fat grafting, where native adipose-derived stem cells present in the transferred tissue can potentially act upon regenerating axons. This review presents the scope of adipose tissue-based therapies to enhance outcomes following peripheral nerve injury, specifically focusing on their role in regeneration and ameliorating neuropathic pain.


2018 ◽  
Vol 46 (6) ◽  
pp. 898-904 ◽  
Author(s):  
Mehrnaz Moattari ◽  
Homa Mohseni Kouchesfehani ◽  
Gholamreza Kaka ◽  
Seyed Homayoon Sadraie ◽  
Majid Naghdi

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