scholarly journals Metabolic syndrome is common and persistent in youth-onset type 2 diabetes: Results from the TODAY clinical trial

Obesity ◽  
2015 ◽  
Vol 23 (7) ◽  
pp. 1357-1361 ◽  
Author(s):  
Ruth S. Weinstock ◽  
Kimberly L. Drews ◽  
Sonia Caprio ◽  
Natasha I. Leibel ◽  
Siripoom Vudhipoom McKay ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Clinical Trial ◽  
Onset Type

Heritability, parental transmission and environment correlation of pediatric-onset type 2 diabetes mellitus and metabolic syndrome-related traits

2017 ◽  
Vol 126 ◽  
pp. 151-159 ◽  
Author(s):  
América L. Miranda-Lora ◽  
Jenny Vilchis-Gil ◽  
Mario Molina-Díaz ◽  
Samuel Flores-Huerta ◽  
Miguel Klünder-Klünder
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Type 2 Diabetes Mellitus ◽  
Onset Type ◽  
Parental Transmission ◽  
Pediatric Onset

Predicting young-onset type 2 diabetes mellitus with metabolic syndrome components in healthy young adults

2018 ◽  
Vol 72 (9) ◽  
pp. e13238
Author(s):  
Chung-Ze Wu ◽  
Jin-Sheun Chen ◽  
Yuh-Feng Lin ◽  
Chang-Hsun Hsieh ◽  
Jiunn-Diann Lin ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Type 2 Diabetes Mellitus ◽  
Young Adults ◽  
Young Onset ◽  
Onset Type ◽  
Metabolic Syndrome Components

scholarly journals Improvement of the metabolic syndrome profile by soluble fibre – guar gum – in patients with type 2 diabetes: a randomised clinical trial

2013 ◽  
Vol 110 (9) ◽  
pp. 1601-1610 ◽  
Author(s):  
Valesca Dall'Alba ◽  
Flávia Moraes Silva ◽  
Juliana Peçanha Antonio ◽  
Thais Steemburgo ◽  
Caroline Persh Royer ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Clinical Trial ◽  
Guar Gum ◽  
Intervention Group ◽  
Interquartile Range ◽  
Soluble Fibre ◽  
The Metabolic Syndrome ◽  
Usual Diet

A diet rich in fibre seems to protect against the metabolic syndrome (MetS), but there is scarce information about the role of fibre intake in patients with the MetS and diabetes. The aim of the present study was to evaluate the effects of soluble fibre from partially hydrolysed guar gum (PHGG) on the MetS and cardiovascular risk factors in patients with type 2 diabetes. In the present randomised controlled clinical trial, forty-four patients with type 2 diabetes (males 38·6 %, age 62 (sd 9) years, diabetes duration 14·2 (sd 9·6) years) and the MetS underwent clinical, laboratory and dietary evaluations at baseline, 4 and 6 weeks. All patients followed their usual diet and the intervention group (n 23) received an additional 10 g/d of PHGG. In the intervention group, waist circumference (WC), glycated Hb (HbA1c), 24 h urinary albumin excretion (UAE) and serum trans-fatty acids (FA) were reduced in comparison with baseline after 4 and 6 weeks: WC 103·5 (sd 9·5) to 102·1 (sd 10) to 102·3 (sd 9·7) cm; HbA1c 6·88 (sd 0·99) to 6·64 (sd 0·94) to 6·57 (sd 0·84) %; 24 h UAE 6·8 (interquartile range 3·0–17·5) to 4·5 (interquartile range 3·0–10·5) to 6·2 (interquartile range 3·0–9·5) mg; trans-FA 71 (interquartile range 46–137) to 67 (interquartile range 48–98) to 57 (interquartile range 30–110) mg/l (P< 0·05 for all). The only change in the control group was weight reduction: 77·0 (sd 13·5) to 76·2 (sd 13·3) to 76·1 (sd 13·4) kg (P= 0·005). Other MetS components (blood pressure, TAG, HDL-cholesterol, fasting plasma glucose), total and LDL-cholesterol, C-reactive protein and endothelin-1 did not change in either group. In patients with type 2 diabetes and the MetS, the addition of PHGG to the usual diet improved cardiovascular and metabolic profiles by reducing WC, HbA1c, UAE and trans-FA.

scholarly journals Long-Term, Randomized Clinical Trial of Two Diets in the Metabolic Syndrome and Type 2 Diabetes

Diabetes Care ◽  
2003 ◽  
Vol 26 (8) ◽  
pp. 2481-2482 ◽  
Author(s):  
L. W. Scott ◽  
A. Balasubramanyam ◽  
K. T. Kimball ◽  
A. K. Aherns ◽  
C. M. Fordis ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
The Metabolic Syndrome

scholarly journals Weight change in the management of youth-onset type 2 diabetes: the TODAY clinical trial experience

2016 ◽  
Vol 12 (4) ◽  
pp. 337-345 ◽  
Author(s):  
M. D. Marcus ◽  
D. E. Wilfley ◽  
L. El ghormli ◽  
P. Zeitler ◽  
B. Linder ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Clinical Trial ◽  
Weight Change ◽  
Onset Type ◽  
Trial Experience ◽  
Clinical Trial Experience
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