Letter to the Editor Regarding “ H. Pylori as a Predictor of Marginal Ulceration: A Nationwide Analysis”

Obesity ◽  
2019 ◽  
Vol 27 (12) ◽  
pp. 1924-1924
Author(s):  
Nicholas Dugan ◽  
Abdelrahman Nimeri
Keyword(s):  
Marginal Ulceration ◽  
Letter To The Editor ◽  
H Pylori

700 H. pylori As a Predictor of Marginal Ulceration: A Nationwide Analysis

2016 ◽  
Vol 83 (5) ◽  
pp. AB164
Author(s):  
Allison Schulman ◽  
Marwan S. Abougergi ◽  
Christopher C. Thompson
Keyword(s):  
Marginal Ulceration ◽  
H Pylori

H. Pylori as a predictor of marginal ulceration: A nationwide analysis

Obesity ◽  
2017 ◽  
Vol 25 (3) ◽  
pp. 522-526 ◽  
Author(s):  
Allison R. Schulman ◽  
Marwan S. Abougergi ◽  
Christopher C. Thompson
Keyword(s):  
Marginal Ulceration ◽  
H Pylori

The rod-to-coccoid body transformation in cultures of Helicobacter pylori

1990 ◽  
Vol 48 (3) ◽  
pp. 626-627
Author(s):  
A. R. Crooker ◽  
W. G. Kraft ◽  
T. L. Beard ◽  
M. C. Myers
Keyword(s):  
Helicobacter Pylori ◽  
Growth Cycle ◽  
Negative Bacterium ◽  
Body Formation ◽  
Coccoid Form ◽  
Spiral Form ◽  
Prolonged Culture ◽  
H Pylori ◽  
Upper Gastrointestinal

Helicobacter pylori is a microaerophilic, gram-negative bacterium found in the upper gastrointestinal tract of humans. There is strong evidence that H. pylori is important in the etiology of gastritis; the bacterium may also be a major predisposing cause of peptic ulceration. On the gastric mucosa, the organism exists as a spiral form with one to seven sheathed flagella at one (usually) or both poles. Short spirals were seen in the first successful culture of the organism in 1983. In 1984, Marshall and Warren reported a coccoid form in older cultures. Since that time, other workers have observed rod and coccal forms in vitro; coccoid forms predominate in cultures 3-7 days old. We sought to examine the growth cycle of H. pylori in prolonged culture and the mode of coccoid body formation.

Vacuoles Induced in Mammalian Cells by Helicobacter Cytotoxin are Acidic Organelles

1990 ◽  
Vol 48 (3) ◽  
pp. 168-169
Author(s):  
M. H. Chestnut ◽  
C. E. Catrenich
Keyword(s):  
Acridine Orange ◽  
Mammalian Cells ◽  
Laser Scanning ◽  
Laser Scanning Microscopy ◽  
Confocal Laser ◽  
Ulcer Disease ◽  
Gastroduodenal Disease ◽  
H Pylori

Helicobacter pylori is a non-invasive, Gram-negative spiral bacterium first identified in 1983, and subsequently implicated in the pathogenesis of gastroduodenal disease including gastritis and peptic ulcer disease. Cytotoxic activity, manifested by intracytoplasmic vacuolation of mammalian cells in vitro, was identified in 55% of H. pylori strains examined. The vacuoles increase in number and size during extended incubation, resulting in vacuolar and cellular degeneration after 24 h to 48 h. Vacuolation of gastric epithelial cells is also observed in vivo during infection by H. pylori. A high molecular weight, heat labile protein is believed to be responsible for vacuolation and to significantly contribute to the development of gastroduodenal disease in humans. The mechanism by which the cytotoxin exerts its effect is unknown, as is the intracellular origin of the vacuolar membrane and contents. Acridine orange is a membrane-permeant weak base that initially accumulates in low-pH compartments. We have used acridine orange accumulation in conjunction with confocal laser scanning microscopy of toxin-treated cells to begin probing the nature and origin of these vacuoles.

Letter to the Editor

1978 ◽  
Vol 9 (3) ◽  
pp. 197-200
Author(s):  
Peter B. Smith
Keyword(s):  
Letter To The Editor

Letter to the Editor

1994 ◽  
Vol 3 (1) ◽  
pp. 89-89
Author(s):  
Lawrence I. Shotland
Keyword(s):  
Letter To The Editor

Letter to the Editor

1994 ◽  
Vol 3 (1) ◽  
pp. 87-87
Author(s):  
David Cieliczka
Keyword(s):  
Letter To The Editor
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