The ulceration-associated cell lineage (UACL) reiterates the Brunner's gland differentiation programme but acquires the proliferative organization of the gastric gland

1994 ◽  
Vol 173 (4) ◽  
pp. 317-326 ◽  
Author(s):  
Dennis J. Ahnen ◽  
Richard Poulsom ◽  
Gordon W. H. Stamp ◽  
George Elia ◽  
Christine Pike ◽  
...  
Keyword(s):  
Gastric Gland ◽  
Cell Lineage ◽  
Brunner’S Gland ◽  
Brunner's Gland

scholarly journals Aspects of the biology of regeneration and repair in the human gastrointestinal tract

1998 ◽  
Vol 353 (1370) ◽  
pp. 925-933 ◽  
Author(s):  
Nicholas A. Wright
Keyword(s):  
Stem Cells ◽  
Gastric Gland ◽  
Cell Lineage ◽  
Mucosal Ulceration ◽  
Cell Lineages ◽  
Trefoil Peptides ◽  
Pyloric Mucosa ◽  
A Cell ◽  
Epidermal Growth ◽  
Altered Gene

The main pathways of epithelial differentiation in the intestine, Paneth, mucous, endocrine and columnar cell lineages are well recognized. However, in abnormal circumstances, for example in mucosal ulceration, a cell lineage with features distinct from these emerges, which has often been dismissed in the past as ‘pyloric’ metaplasia, because of its morphological resemblance to the pyloric mucosa in the stomach. However, we can conclude that this cell lineage has a defined phenotype unique in gastrointestinal epithelia, has a histogenesis that resembles that of Brunner's glands, but acquires a proliferative organization similar to that of the gastric gland. It expresses several peptides of particular interest, including epidermal growth factor, the trefoil peptides TFF1, TFF2, TFF3, lysozyme and PSTI. The presence of this lineage also appears to cause altered gene expression in adjacent indigenous cell lineages. We propose that this cell lineage is induced in gastrointestinal stem cells as a result of chronic mucosal ulceration, and plays an important part in ulcer healing; it should therefore be added to the repertoire of gastrointestinal stem cells.

Endoscopic Removal of a Large, Obstructing and Bleeding Duodenal Brunner's Gland Adenoma

Endoscopy ◽  
1985 ◽  
Vol 17 (06) ◽  
pp. 231-232 ◽  
Author(s):  
Oth. Kehl ◽  
H. Bühler ◽  
B. Stamm ◽  
R.W. Amman
Keyword(s):  
Endoscopic Removal ◽  
Brunner’S Gland ◽  
Brunner's Gland

Brunner's gland hyperplasia causing gastric outlet obstruction in a 3-year-old child

2016 ◽  
Vol 102 (3) ◽  
pp. 231-231 ◽  
Author(s):  
Lucy Henderson ◽  
Cathy Richards ◽  
Anne Willmott ◽  
Haitham Dagash
Keyword(s):  
Gastric Outlet Obstruction ◽  
Outlet Obstruction ◽  
Brunner’S Gland ◽  
Brunner's Gland

scholarly journals A Case of Brunner's Gland Adenoma Presenting as Large Polyp with Stalk

2012 ◽  
Vol 12 (1) ◽  
pp. 47 ◽  
Author(s):  
Eun Mi Song ◽  
Ki-Nam Shim ◽  
Hye Won Kang ◽  
Ju Young Choi ◽  
Seong-Eun Kim ◽  
...  
Keyword(s):  
Large Polyp ◽  
Brunner’S Gland ◽  
Brunner's Gland

scholarly journals A case of giant Brunner's gland hyperplasia complicated with acute pancreatitis

2007 ◽  
Vol 71 (2) ◽  
pp. 88-89 ◽  
Author(s):  
Eiko Saito ◽  
Yukinori Imai ◽  
Yoshie Mizuno ◽  
Satsuki Ando ◽  
Kayoko Sugawara ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Brunner’S Gland ◽  
Brunner's Gland

Adenoma of brunner's gland—a report of two cases

1968 ◽  
Vol 55 (2) ◽  
pp. 119-120 ◽  
Author(s):  
K. L. Jain ◽  
A. A. El Tayeb
Keyword(s):  
Brunner’S Gland ◽  
Brunner's Gland
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