Biodegradable polymer blends: miscibility, physicochemical properties and biological response of scaffolds

2015 ◽  
Vol 64 (10) ◽  
pp. 1289-1302 ◽  
Author(s):  
Nowsheen Goonoo ◽  
Archana Bhaw-Luximon ◽  
Dhanjay Jhurry
2014 ◽  
Vol 31 (12) ◽  
pp. 3379-3389 ◽  
Author(s):  
Sarita R. Shah ◽  
Allan M. Henslee ◽  
Patrick P. Spicer ◽  
Shun Yokota ◽  
Sophia Petrichenko ◽  
...  

2019 ◽  
Vol 54 (12) ◽  
pp. 1170-1185 ◽  
Author(s):  
Kamaljeet Kaur ◽  
Isabel C. Jaramillo ◽  
Raziye Mohammadpour ◽  
Anne Sturrock ◽  
Hamidreza Ghandehari ◽  
...  

Nanomaterials ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 1930
Author(s):  
Mai T. Huynh ◽  
Jean Francois Veyan ◽  
Hong Pham ◽  
Raina Rahman ◽  
Samad Yousuf ◽  
...  

The biological response of multi-walled carbon nanotubes (MWNTs) is related to their physicochemical properties and a thorough MWNT characterization should accompany an assessment of their biological activity, including their potential toxicity. Beyond characterizing the physicochemical properties of MWNTs from different sources or manufacturers, it is also important to characterize different production lots of the same MWNT product from the same vendor (i.e., lot-to-lot batch consistency). Herein, we present a comprehensive physicochemical characterization of two lots of commercial pristine MWNTs (pMWNTs) and carboxylated MWNTs (cMWNTs) used to study the response of mammalian macrophages to MWNTs. There were many similarities between the physicochemical properties of the two lots of cMWNTs and neither significantly diminished the 24-h proliferation of RAW 264.7 macrophages up to the highest concentration tested (200 μg cMWNTs/mL). Conversely, several physicochemical properties of the two lots of pMWNTs were different; notably, the newer lot of pMWNTs displayed less oxidative stability, a higher defect density, and a smaller amount of surface oxygen species relative to the original lot. Furthermore, a 72-h half maximal inhibitory concentration (IC-50) of ~90 µg pMWNTs/mL was determined for RAW 264.7 cells with the new lot of pMWNTs. These results demonstrate that subtle physicochemical differences can lead to significantly dissimilar cellular responses, and that production-lot consistency must be considered when assessing the toxicity of MWNTs.


Author(s):  
Mihir Sheth ◽  
R. Ananda Kumar ◽  
Vipul Dav� ◽  
Richard A. Gross ◽  
Stephen P. McCarthy

2016 ◽  
Vol 137 ◽  
pp. 452-458 ◽  
Author(s):  
J.F. Mendes ◽  
R.T Paschoalin ◽  
V.B. Carmona ◽  
Alfredo R Sena Neto ◽  
A.C.P. Marques ◽  
...  

Polymer ◽  
2012 ◽  
Vol 53 (21) ◽  
pp. 4787-4799 ◽  
Author(s):  
Seongchan Pack ◽  
Ezra Bobo ◽  
Neil Muir ◽  
Kai Yang ◽  
Sufal Swaraj ◽  
...  

2012 ◽  
Vol 51 (14) ◽  
pp. 1432-1442 ◽  
Author(s):  
Pavel Kucharczyk ◽  
Onon Otgonzu ◽  
Takeshi Kitano ◽  
Adriana Gregorova ◽  
Darij Kreuh ◽  
...  

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