Direct analytical sample quality assessment for biomarker investigation: Qualifying cerebrospinal fluid samples

PROTEOMICS ◽  
2014 ◽  
Vol 14 (17-18) ◽  
pp. 1954-1962 ◽  
Author(s):  
Viviana Greco ◽  
Damiana Pieragostino ◽  
Cristian Piras ◽  
Ruedi Aebersold ◽  
Jens Wiltfang ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Quality Assessment ◽  
Sample Quality

scholarly journals Shear wave Velocities for Sample Quality Assessment on a Residual Soil

2011 ◽  
Vol 51 (4) ◽  
pp. 683-692 ◽  
Author(s):  
Cristiana Ferreira ◽  
António Viana da Fonseca ◽  
David F.T. Nash
Keyword(s):  
Quality Assessment ◽  
Shear Wave ◽  
Residual Soil ◽  
Sample Quality ◽  
Wave Velocities ◽  
Shear Wave Velocities

The necessity of sample quality assessment in 14C AMS dating: The case of Cova des Pas (Menorca – Spain)

2010 ◽  
Vol 268 (7-8) ◽  
pp. 990-994 ◽  
Author(s):  
Mark Van Strydonck ◽  
Mathieu Boudin ◽  
Víctor M. Guerrero Ayuso ◽  
Manuel Calvo ◽  
Josep M. Fullola ◽  
...  
Keyword(s):  
Quality Assessment ◽  
Sample Quality ◽  
Ams Dating

scholarly journals Human DNA quantification and sample quality assessment: Developmental validation of the PowerQuant ¨r) system

2016 ◽  
Vol 23 ◽  
pp. 166-177 ◽  
Author(s):  
Margaret M. Ewing ◽  
Jonelle M. Thompson ◽  
Robert S. McLaren ◽  
Vincent M. Purpero ◽  
Kelli J. Thomas ◽  
...  
Keyword(s):  
Quality Assessment ◽  
Dna Quantification ◽  
Sample Quality ◽  
Human Dna ◽  
Developmental Validation

scholarly journals PDZ Sample Quality Assessment by Biochemical and Biophysical Characterizations

2021 ◽  
pp. 89-124
Author(s):  
Célia Caillet-Saguy ◽  
Sébastien Brûlé ◽  
Nicolas Wolff ◽  
Bertrand Raynal
Keyword(s):  
Quality Assessment ◽  
Sample Quality

scholarly journals NMR for sample quality assessment in metabolomics

2019 ◽  
Vol 52 ◽  
pp. 25-34 ◽  
Author(s):  
Veronica Ghini ◽  
Deborah Quaglio ◽  
Claudio Luchinat ◽  
Paola Turano
Keyword(s):  
Quality Assessment ◽  
Sample Quality

External quality assessment in clinical neurochemistry: survey of analysis for cerebrospinal fluid (CSF) proteins based on CSF/serum quotients

1995 ◽  
Vol 41 (2) ◽  
pp. 256-263 ◽  
Author(s):  
H Reiber
Keyword(s):  
Cerebrospinal Fluid ◽  
Quality Assessment ◽  
External Quality Assessment ◽  
Internal Quality ◽  
Barrier Dysfunction ◽  
External Quality ◽  
Csf Analysis ◽  
Csf Proteins ◽  
Oligoclonal Igg

Abstract Participants (230) from Germany and 20 laboratories in 11 European countries took part in a newly designed cerebrospinal fluid (CSF) survey distributed by INSTAND. Conventional proficiency testing for albumin, IgG, IgA, and IgM in CSF and serum, for total protein in CSF, and for oligoclonal IgG in CSF and serum was combined with evaluation and interpretation of CSF/serum quotients in quotient diagrams. The correct detection of a blood-CSF barrier dysfunction and the pattern of intrathecal immunoglobulin synthesis was judged. The accuracy of CSF/serum quotients and their clinically relevant interpretation was given first priority as a new concept in quality assessment. The main result of the surveys was to confirm that CSF/serum quotients of proteins represent method-independent values approaching the quality of reference values. This finding has consequences for internal quality control of CSF analysis and for accreditation bodies. The sensitivity of the methods for quantifying IgA and IgM in CSF and for detecting oligoclonal IgG fractions is discussed.

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