scholarly journals Correlates of quality of life-related outcomes in breast cancer patients participating in the Pathfinders pilot study

2011 ◽  
Vol 20 (5) ◽  
pp. 559-564 ◽  
Author(s):  
Sophia K. Smith ◽  
James E. Herndon ◽  
H. Kim Lyerly ◽  
April Coan ◽  
Jane L. Wheeler ◽  
...  
2011 ◽  
Vol 52 (1) ◽  
pp. 184-193 ◽  
Author(s):  
Carlos Eduardo Paiva ◽  
Bianca Sakamoto Ribeiro Paiva ◽  
Rafael Amaral de Castro ◽  
Cristiano de Pádua Souza ◽  
Yara Cristina de Paiva Maia ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Wilfried Tröger ◽  
Zdravko Ždrale ◽  
Nevena Tišma ◽  
Miodrag Matijašević

Background. Breast cancer patients receiving adjuvant chemotherapy often experience a loss of quality of life. Moreover chemotherapy may induce neutropenia. Patients report a better quality of life when additionally treated with mistletoe products during chemotherapy.Methods. In this prospective randomized open-label pilot study 95 patients were randomized into three groups. All patients were treated with an adjuvant chemotherapy. The primary objective of the study was quality of life, the secondary objective was neutropenia. Here we report the comparison of HxA (n= 34) versus untreated control (n= 31).Results. In the explorative analysis ten of 15 scores of the EORTC QLQ-C30 showed a better quality of life in the HxA group compared to the control group (P<0.001toP=0.038in Dunnett-T3 test). The difference was clinically relevant (difference of at least 5 points, range 5.4–12.2) in eight of the ten scores. Neutropenia occurred in 7/34 HxA patients and in 8/31 control patients (P= 0.628).Conclusions. This pilot study showed an improvement of quality of life by treating breast cancer patients with HxA additionally to CAF. Although the open design may be a limitation, the findings show the feasibility of a confirmatory study using the methods described here.


2013 ◽  
Vol 2013 (1) ◽  
pp. 4454
Author(s):  
Soo Rim Noh ◽  
Wang Lim Lee ◽  
Hee Sung Shin ◽  
Min Sun Lee ◽  
Tae Seon Baek ◽  
...  

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