Long-term noninvasive mechanical ventilation for children at home: A national survey

2003 ◽  
Vol 35 (2) ◽  
pp. 119-125 ◽  
Author(s):  
B. Fauroux ◽  
C. Boffa ◽  
I. Desguerre ◽  
B. Estournet ◽  
H. Trang ◽  
...  
CHEST Journal ◽  
2020 ◽  
Vol 158 (6) ◽  
pp. 2493-2501 ◽  
Author(s):  
Ries J.M. van den Biggelaar ◽  
Anda Hazenberg ◽  
Nicolle A.M. Cobben ◽  
Michael A. Gaytant ◽  
Karin M. Vermeulen ◽  
...  

Author(s):  
Mihail Basa ◽  
Predrag Minic ◽  
Aleksandar Sovtic ◽  
Milan Rodic

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S447-S447
Author(s):  
Jeremy M Jacobs ◽  
Esther-Lee Marcus ◽  
Jochanan Stessman

Abstract Rising numbers of patients receiving Prolonged Mechanical Ventilation (PMV) pose a challenge, and advancing technology supports ventilators appropriate for either Home or Hospital Long Term Care (HLTC).Data guiding decisions concerning place of care are lacking. This study describes the characteristics of the majority (120/123) of all PMV patients aged ≥18 (and their caregivers) in Jerusalem, covered by the Clalit Health Service, treated either with Home Hospital or HLTC. Patients were more alert and communicative at Home vs. HLTC (40/46 vs. 22/74), younger (54 vs.73 years, p12 years (36% vs.21%, p=0.1), and without legal guardian (59% vs. 12%, p<0.01). Primary reason for PMV at home was degenerative neuromuscular disease (59% vs. 28%), compared to post resuscitation/sepsis/CVA in HLTC patients (17% vs. 62%), who suffered more comorbidity, functional decline post-PMV, and pressure sores (0% vs. 42%). Ventilation was more likely to be planned at home vs HLTC (33% vs. 8%), and yet 119/120 were without Advanced Directives prior to PMV. Caregivers at home tended to be spouses (48% vs. 31%) and offspring at HLTC (17% vs. 47%), with reduced Modified Caregiver Strain Index at home (10.5 vs. 12.9, p=0.12). Mortality during follow-up was lower at home (15.2% vs. 27%). Costs to the health fund for home versus HLTC were approximately 1:3. Our findings suggest that with appropriate targeting of eligible PMV patients, Home Hospital may be the preferred model of care for patients, caregivers and healthcare providers.


2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Gregorino Paone ◽  
Vittoria Conti ◽  
Giuseppe Biondi-Zoccai ◽  
Elena De Falco ◽  
Isotta Chimenti ◽  
...  

Background. Long-term home noninvasive mechanical ventilation (NIV) is beneficial in COPD but its impact on inflammation is unknown. We assessed the hypothesis that NIV modulates systemic and pulmonary inflammatory biomarkers in stable COPD.Methods. Among 610 patients referred for NIV, we shortlisted those undergoing NIV versus oxygen therapy alone, excluding subjects with comorbidities or non-COPD conditions. Sputum and blood samples were collected after 3 months of clinical stability and analyzed for levels of human neutrophil peptides (HNP), interleukin-6 (IL-6), interleukin-10 (IL-10), and tumor necrosis factor-alpha (TNF-alpha). Patients underwent a two-year follow-up. Unadjusted, propensity-matched, and pH-stratified analyses were performed.Results. Ninety-three patients were included (48 NIV, 45 oxygen), with analogous baseline features. Sputum analysis showed similar HNP, IL-6, IL-10, and TNF-alpha levels (P>0.5). Conversely, NIV group exhibited higher HNP and IL-6 systemic levels (P<0.001) and lower IL-10 concentrations (P<0.001). Subjects undergoing NIV had a significant reduction of rehospitalizations during follow-up compared to oxygen group (P=0.005). These findings were confirmed after propensity matching and pH stratification.Conclusions. These findings challenge prior paradigms based on the assumption that pulmonary inflammation isper sedetrimental. NIV beneficial impact on lung mechanics may overcome the potential unfavorable effects of an increased inflammatory state.


CHEST Journal ◽  
2002 ◽  
Vol 121 (2) ◽  
pp. 321-324 ◽  
Author(s):  
Allen I. Goldberg

CHEST Journal ◽  
1992 ◽  
Vol 101 (6) ◽  
pp. 1483-1484 ◽  
Author(s):  
Allen I. Goldberg

2008 ◽  
Vol 32 (2) ◽  
pp. 460-464 ◽  
Author(s):  
S. Nava ◽  
S. Cirio ◽  
F. Fanfulla ◽  
A. Carlucci ◽  
A. Navarra ◽  
...  

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