Preoperative MRI PI‐RADS scores are associated with prostate cancer upstaging on surgical pathology

The Prostate ◽  
2021 ◽  
Author(s):  
Benjamin Pockros ◽  
Kristian D. Stensland ◽  
Molly Parries ◽  
Edward Frankenberger ◽  
David Canes ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Surgical Pathology

Surgical Pathology of Prostate Cancer

2008 ◽  
pp. 160-188
Author(s):  
C. S. Foster
Keyword(s):  
Prostate Cancer ◽  
Surgical Pathology

Adequacy of Surgical Pathology Reporting of Cancer: A College of American Pathologists Q-Probes Study of 86 Institutions

2010 ◽  
Vol 134 (7) ◽  
pp. 969-974 ◽  
Author(s):  
Michael O. Idowu ◽  
Leonas G. Bekeris ◽  
Stephen Raab ◽  
Stephen G. Ruby ◽  
Raouf E. Nakhleh
Keyword(s):  
Prostate Cancer ◽  
Patient Care ◽  
Resection Margin ◽  
Surgical Pathology ◽  
Optimal Patient Care ◽  
Pathology Reporting ◽  
Pathology Reports ◽  
Tumor Types

Abstract Context.—Inclusion of all scientifically validated elements in surgical pathology cancer reports is needed for optimal patient care. Objective.—To evaluate the frequency with which surgical pathology cancer reports contain all the scientifically validated elements required by the American College of Surgery (ACS) Commission on Cancer (CoC), the extent to which checklists are used, and the effects that the use of checklists have on the completeness of cancer reports. Design.—Participants in the College of American Pathologists voluntary Q-Probes program reviewed 25 consecutive surgical pathology reports to include cancer reports from breast, colon, rectum, and prostate cancer specimens. For each report, the type and total number of missing required elements, deemed essential by the ACS CoC, was recorded. Results.—A total of 2125 cancer reports were reviewed in 86 institutions; 68.8% of all surgical pathology cancer reports included all the required elements. Institutions in which checklists were routinely used reported all required elements at a higher rate than those that did not use checklists (88% versus 34%), and institutions that had a system in place to track errors also reported all required elements at a higher rate when compared to those that did not have such a system in place (88% versus 68%). The missing mandated elements, common to cancer reports of all tumor types, were extent of invasion and status of the resection margin. Conclusions.—This study demonstrates that about 30% of cancer reports do not have all the scientifically validated elements required by the ACS CoC. Pathology departments in which checklists are not routinely used have a substantially lower rate of reports that include all the required elements.

Surgical Pathology—Second Reviews, Institutional Reviews, Audits, and Correlations: What's Out There? Error or Diagnostic Variation?

2006 ◽  
Vol 130 (5) ◽  
pp. 620-625
Author(s):  
William J. Frable
Keyword(s):  
Prostate Cancer ◽  
Gleason Score ◽  
Medical Literature ◽  
Diagnostic Errors ◽  
Error Rates ◽  
Surgical Pathology ◽  
Risk Category ◽  
Anatomic Site ◽  
The Media ◽  
Thyroid Lesions

Abstract Context.—A variety of methodologies have been used to report error rates in surgical pathology within the peer-reviewed medical literature. The media has selectively and superficially reported these error rates creating a climate of disinformation between physicians and the public. Objectives.—To review the medical literature on diagnostic error in surgical pathology and summarize and compare these data with selected reports in the print and broadcast media. Design.—A search of the medical literature from the National Library of Medicine database using the heading “Error and Pathology Diagnosis.” Results.—Three thousand nine hundred ninety-two citations were found, of which 83 directly measured in some manner errors in surgical and cytopathology. Major error rates ranged from 1.5% to 5.7% globally for institutional consults. Error rates were less, 0.26% to 1.2% for global in-house prospective review and 4.0% for in-house and retrospective blinded review. Error rates also varied by anatomic site: skin, institutional consult, 1.4%; prostate, institutional consult, 0.5%; and thyroid, institutional consult, 7.0%. Error rates reported in citations used by the Wall Street Journal were as follows: prostate, Gleason score changed by 1 point, 44% and resultant change in treatment for prostate cancer, 10%; for breast, altered lumpectomy or mastectomy plan, 8%; and diagnosis changed for thyroid lesions, 18%. Errors in second opinion on breast lesions (single pathologist author for the study) fall within the range of global reviews. Errors for second opinions on prostate cancer were principally 81% upgrades in Gleason score for prostate core needle biopsies. However, this resulted in an upgrade of patient risk category in only 10.8% of patients. Data for the article on change in diagnosis of thyroid lesions were incomplete. There appeared to be 3 significant diagnostic errors (4.5%). Conclusions.—Pathology is not immune to the power of the media to create concern about accuracy of diagnosis in surgical pathology and cytopathology. Detailed analysis of the medical literature cited by the media determines that painting the big picture and hitting the highlights can be profoundly misleading.

scholarly journals Anatomy of the prostate gland and surgical pathology of prostate cancer

2011 ◽  
pp. 1-14 ◽  
Author(s):  
Kai H. Hammerich ◽  
Gustavo E. Ayala ◽  
Thomas M. Wheeler
Keyword(s):  
Prostate Cancer ◽  
Prostate Gland ◽  
Surgical Pathology

scholarly journals LESSONS FOR COVID 19 ERA: IMPACT OF DELAYS IN SURGERY ON BIOCHEMICAL RECURRENCE-FREE SURVIVAL AND ADVERSE ONCOLOGICAL OUTCOMES IN PROSTATE CANCER PATIENTS

2021 ◽  
Author(s):  
Bahadir Sahin ◽  
Ozan Bozkurt ◽  
Sinan Sözen ◽  
Haluk Ozen ◽  
Bulent Akdogan ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
High Risk ◽  
Seminal Vesicle ◽  
Biochemical Recurrence ◽  
Surgical Pathology ◽  
Recurrence Free Survival ◽  
Free Survival ◽  
Surgical Delay ◽  
Oncological Outcomes ◽  
Group 1

OBJECTIVE To assess the impact of the surgical delay for localized prostate cancer (PCa) on adverse pathological features and oncological outcomes. MATERIALS AND METHODS Patients who underwent surgery for localized prostate cancer were included from the Turkish Urooncology Association (TUA) Prostate Cancer database. A History of previous treatment or active surveillance (AS) were considered as exclusion criteria from the study. Patients were divided into two groups according the time period between the diagnosis and surgery; less than or equal to 90 days (group 1) or longer than 90 days (group 2). Surgical pathology results and oncological outcomes were compared between the two groups. RESULTS A total of 2454 out of 3646 patients were assessed. Pathological findings of the radical prostatectomy (RP) specimens were similar between two groups. However, there was slightly more seminal vesicle invasion in final surgical pathology in group 1 (12.9% vs. 9.3%, respectively p=0.042). 5-year biochemical recurrence free survival times were similar across all D’Amico risk categories between two groups. The regression analysis demonstrated the seminal vesicle invasion as the only factor affecting time to PSA progression in high-risk patients (p<0.001 HR:2.51 CI: 1,58-4,45). CONCLUSION In conclusion, our results in this large cohort suggest that surgical delay does not cause a deterioration for prostate cancer surgical outcomes even in high-risk group of patients. These findings may be helpful for planning the limited healthcare resources especially in conditions like the Covid-19 pandemic where the availability and optimal use of healthcare system resources is crucial.

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