scholarly journals Impacts of anti‐inflammatory phosphodiesterase inhibitors on a murine model of chronic pulmonary inflammation

2021 ◽  
Vol 9 (4) ◽  
Author(s):  
Xiao‐Fang Zheng ◽  
Dan‐Dan Chen ◽  
Xiao‐Ling Zhu ◽  
Jehane Michael Le Grange ◽  
Lu‐Qian Zhou ◽  
...  
Keyword(s):  
Murine Model ◽  
Pulmonary Inflammation ◽  
Phosphodiesterase Inhibitors ◽  
Anti Inflammatory

scholarly journals RU486 blocks the anti-inflammatory effects of exercise in a murine model of allergen-induced pulmonary inflammation

2005 ◽  
Vol 19 (5) ◽  
pp. 413-422 ◽  
Author(s):  
Amy Pastva ◽  
Kim Estell ◽  
Trenton R. Schoeb ◽  
Lisa M. Schwiebert
Keyword(s):  
Murine Model ◽  
Pulmonary Inflammation ◽  
Anti Inflammatory

scholarly journals Reduction of Pulmonary Inflammation by pH Modifiers

2022 ◽  
Author(s):  
Wei-ping Zeng
Keyword(s):  
Pulmonary Inflammation ◽  
Inflammatory Cells ◽  
Pathological Feature ◽  
Successful Therapy ◽  
Mucus Hypersecretion ◽  
Adverse Side Effects ◽  
New Class ◽  
Asthma Model ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Abstract Pulmonary inflammation is a common pathological feature of a variety of diseases, ofwhich successful therapy with currently available anti-inflammatory drugs is limited byresistance and adverse side effects. Using the ovalbumin-induced mouse allergic asthma model,the present study shows that treatments with pH modifiers, particularly simple acids such asacetate or hydrochloric acid, effectively depleted inflammatory cells in the lungs and blood aswell as hyperplastic lung tissue cells while preserving the structure of the blood vessels and lungparenchyma. The acid treatments also suppressed mucus hypersecretion. These resultsdemonstrated pH modifiers as a new class of broad-spectrum anti-inflammatory agents with antiproliferationand mucus suppression activities.

scholarly journals CCR2 Mediates Chronic LPS-Induced Pulmonary Inflammation and Hypoalveolarization in a Murine Model of Bronchopulmonary Dysplasia

2020 ◽  
Vol 11 ◽  
Author(s):  
Tracy X. Cui ◽  
Alexander E. Brady ◽  
Christina T. Fulton ◽  
Ying-Jian Zhang ◽  
Liza M. Rosenbloom ◽  
...  
Keyword(s):  
Bronchopulmonary Dysplasia ◽  
Murine Model ◽  
Pulmonary Inflammation

Anti-Inflammatory Effects of Eugenol and Dehydrodieugenol in a Murine Model of Allergic Asthma

2019 ◽  
Author(s):  
F.P. Roncon ◽  
R.C. Silva ◽  
V. Ponci ◽  
C.R. Olivo ◽  
F.M. Arantes-Costa ◽  
...  
Keyword(s):  
Allergic Asthma ◽  
Murine Model ◽  
Anti Inflammatory
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