Predictive Performance of Physiologically Based Pharmacokinetic and Population Pharmacokinetic Modeling of Renally Cleared Drugs in Children

Bottom-up Meets Top-down: Complementary Physiologically Based Pharmacokinetic and Population Pharmacokinetic Modeling for Regulatory Approval of a Dosing Algorithm of Valganciclovir in Very Young Children

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.449 ◽

2016 ◽

Vol 100 (6) ◽

pp. 761-769 ◽

Cited By ~ 14

Author(s):

K Jorga ◽

C Chavanne ◽

N Frey ◽

T Lave ◽

V Lukacova ◽

...

Keyword(s):

Young Children ◽

Regulatory Approval ◽

Top Down ◽

Very Young Children ◽

Dosing Algorithm ◽

Comparison Between Physiologically Based Pharmacokinetic and Population Pharmacokinetic Modeling to Select Paediatric Doses of Gepotidacin in Plague

British Journal of Clinical Pharmacology ◽

10.1111/bcp.14996 ◽

2021 ◽

Author(s):

Dung Nguyen ◽

Jafar Sadik Shaik ◽

Guoying Tai ◽

Courtney Tiffany ◽

Caroline Perry ◽

...

Keyword(s):

Physiologically Based Population Pharmacokinetic Modeling Approach for Ciprofloxacin in Bone of Patients Undergoing Orthopedic Surgery

ACS Pharmacology & Translational Science ◽

10.1021/acsptsci.0c00045 ◽

2020 ◽

Vol 3 (3) ◽

pp. 444-454 ◽

Cited By ~ 1

Author(s):

Cornelia B. Landersdorfer ◽

Martina Kinzig ◽

Rainer Höhl ◽

Peter Kempf ◽

Roger L. Nation ◽

...

Keyword(s):

Orthopedic Surgery ◽

Modeling Approach ◽

Application of Physiologically‐Based and Population Pharmacokinetic Modeling for Dose Finding and Confirmation During the Pediatric Development of Moxifloxacin

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12446 ◽

2019 ◽

Vol 8 (9) ◽

pp. 654-663 ◽

Cited By ~ 2

Author(s):

Stefan Willmann ◽

Matthias Frei ◽

Gabriele Sutter ◽

Katrin Coboeken ◽

Thomas Wendl ◽

...

Keyword(s):

Dose Finding ◽

Establishing virtual bioequivalence and clinically relevant specifications using in vitro biorelevant dissolution testing and physiologically-based population pharmacokinetic modeling. case example: Naproxen

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2019.105170 ◽

2020 ◽

Vol 143 ◽

pp. 105170 ◽

Cited By ~ 8

Author(s):

Ioannis Loisios-Konstantinidis ◽

Rodrigo Cristofoletti ◽

Nikoletta Fotaki ◽

David B. Turner ◽

Jennifer Dressman

Keyword(s):

Dissolution Testing ◽

Clinically Relevant Specifications

Biorelevant Dissolution ◽

Physiologically Based ◽

Use of Physiologically Based Pharmacokinetic Modeling for Predicting Drug–Food Interactions: Recommendations for Improving Predictive Performance of Low Confidence Food Effect Models

The AAPS Journal ◽

10.1208/s12248-021-00601-0 ◽

2021 ◽

Vol 23 (4) ◽

Author(s):

Christian Wagner ◽

Filippos Kesisoglou ◽

Xavier J. H. Pepin ◽

Neil Parrott ◽

Arian Emami Riedmaier

Keyword(s):

Food Effect ◽

Predictive Performance ◽

Physiologically-based pharmacokinetic modeling of different size polyethylene glycol-coated gold nanoparticles in mice

10.1615/ihtc16.nmt.023362 ◽

2018 ◽

Author(s):

Linjing Deng ◽

Jinping Zhao ◽

Yufeng Miao ◽

Xu Hu ◽

Qihong Deng

Keyword(s):

Gold Nanoparticles ◽

Polyethylene Glycol ◽

Physiologically-Based Pharmacokinetic Modeling to Predict Changes in Drug Exposure during Pregnancy Using the Simcyp Simulator

10.26226/morressier.57d6b2b7d462b8028d88e945 ◽

2016 ◽

Author(s):

Suvarchala Kiranmai Avvari

Keyword(s):

Drug Exposure ◽

Physiologically Based ◽

Exposure During Pregnancy

Physiologically‐Based Pharmacokinetic Modeling of Atorvastatin Incorporating Delayed Gastric Emptying and Acid‐to‐Lactone Conversion

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12447 ◽

2019 ◽

Vol 8 (9) ◽

pp. 664-675 ◽

Cited By ~ 5

Author(s):

Bridget L. Morse ◽

Jeffrey J. Alberts ◽

Maria M. Posada ◽

Jessica Rehmel ◽

Anil Kolur ◽

...

Keyword(s):

Gastric Emptying ◽

Delayed Gastric Emptying ◽

Preliminary physiologically based pharmacokinetic modeling of renally cleared drugs in Chinese pregnant women

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2243 ◽

2020 ◽

Vol 41 (6) ◽

pp. 248-267 ◽

Cited By ~ 1

Author(s):

Ling Song ◽

Zhiheng Yu ◽

Yifan Xu ◽

Xiaobei Li ◽

Xuanlin Liu ◽

...

Keyword(s):

Pregnant Women ◽