Antiviral activity of the infusion (SHS-174) from flowers ofSambucus nigra L., aerial parts ofHypericum perforatum L., and roots ofSaponaria officinalis L. against influenza and herpes simplex viruses

1990 ◽  
Vol 4 (3) ◽  
pp. 97-100 ◽  
Author(s):  
Julia Serkedjieva ◽  
Nadia Manolova ◽  
Izabella Zgórniak-Nowosielska ◽  
Barbara Zawilińska ◽  
Jan Grzybek
Keyword(s):  
Herpes Simplex ◽  
Antiviral Activity ◽  
Herpes Simplex Viruses ◽  
Aerial Parts

Antiviral Activity of 5-Ethyl-2'-Deoxyuridine against Herpes Simplex Viruses in Cell Culture, Mice, and Guinea Pigs

1985 ◽  
Vol 28 (6) ◽  
pp. 851-851
Author(s):  
R. F. Schinazi ◽  
R. T. Scott ◽  
J. Peters ◽  
V. Rice ◽  
A. J. Nahmias
Keyword(s):  
Cell Culture ◽  
Herpes Simplex ◽  
Antiviral Activity ◽  
Guinea Pigs ◽  
Herpes Simplex Viruses

Antiviral Activity of CP-20,961 against Herpes Simplex Viruses in vitro

Intervirology ◽  
1985 ◽  
Vol 23 (1) ◽  
pp. 44-50 ◽  
Author(s):  
Z.M. Zheng ◽  
D.R. Mayo ◽  
C.K.Y. Fong ◽  
T. Winship ◽  
G.D. Hsiung
Keyword(s):  
Herpes Simplex ◽  
Antiviral Activity ◽  
Herpes Simplex Viruses

Antiviral Activity of Eight Commonly Used Medicinal Plants in Taiwan

2003 ◽  
Vol 31 (06) ◽  
pp. 897-905 ◽  
Author(s):  
Lien-Chai Chiang ◽  
Hua-Yew Cheng ◽  
Mei-Chi Liu ◽  
Wen Chiang ◽  
Chun-Ching Lin
Keyword(s):  
Natural Products ◽  
Herpes Simplex ◽  
Medicinal Plants ◽  
Antiviral Activity ◽  
Antiviral Agents ◽  
Hot Water ◽  
Herpes Simplex Viruses ◽  
Water Extracts

In an effort to find new antiviral agents from natural products, hot water extracts of eight traditionally used medicinal plants in Taiwan were investigated in vitro for their activities against adenoviruses (ADV) and herpes simplex viruses (HSV). Results demonstrated that all extracts exhibited antiviral activity with different degrees of potency. Only two extracts were active in suppressing both HSV and ADV infections. Three extracts inhibited only ADV infection whereas one extract blocked only HSV infection. These results suggested that the aforementioned medicinal plants merit further investigation.

scholarly journals In vitro antiviral activity of BanLec against herpes simplex viruses type 1 and 2

2020 ◽  
Vol 15 (1) ◽  
pp. 11-18
Author(s):  
Arisha Taj Mahaboob Batcha ◽  
Ashish Wadhwani ◽  
Gowri Subramaniam
Keyword(s):  
Herpes Simplex ◽  
Antiviral Activity ◽  
Selectivity Index ◽  
Antiviral Compound ◽  
Herpes Simplex Viruses ◽  
Antiviral Activities ◽  
Simplex Virus ◽  
Hsv 1

The present study evaluates the antiviral activity of banana lectin (BanLec) against herpes simplex virus type 1 and 2 (HSV-1 and HSV-2). Lectin was isolated from the ripen pulp of bananas (Musa paradisiaca). The study showed that lectin exhibited hemagglutination activity towards human erythrocytes A, B, AB and O group. The molecular weight of BanLec using SDS gel-electrophoresis was found to be 14,000-30,000 Da. Cytotoxicity of BanLec on the Vero cell lines showed an inhibitory concentration of 172.7 µg/mL. BanLec was virucidal and showed no cytotoxicity at the concentration tested. The lectin showed a dose-dependent antiviral activities, inhibiting HSV-1 by 16.0 µg/mL with selectivity index 10.8 and HSV-2 inhibition by 67.7 µg/mL with selectivity index 2.6. These results corroborate that BanLec could be a rich source of potential antiviral compound for HSV-1 when compared to HSV-2.

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