Screening for Anti-inflammatory and Bronchorelaxant Activities of 12 Commonly Used Chinese Herbal Medicines

2011 ◽  
Vol 26 (6) ◽  
pp. 915-925 ◽  
Author(s):  
Grace G. L. Yue ◽  
Ben C. L. Chan ◽  
Hin-Fai Kwok ◽  
Ming-Ho To ◽  
Kam-Lun Hon ◽  
...  
Keyword(s):  
Herbal Medicines ◽  
Chinese Herbal Medicines ◽  
Chinese Herbal ◽  
Anti Inflammatory

scholarly journals Mechanisms and Efficacy of Chinese Herbal Medicines in Chronic Kidney Disease

2021 ◽  
Vol 11 ◽  
Author(s):  
Mingming Zhao ◽  
Yi Yu ◽  
Rumeng Wang ◽  
Meiying Chang ◽  
Sijia Ma ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Clinical Trials ◽  
Kidney Disease ◽  
Molecular Mechanisms ◽  
Herbal Medicines ◽  
Small Sample ◽  
Chinese Herbal Medicines ◽  
Chinese Herbal ◽  
Anti Inflammatory ◽  
Meta Analyses

As the current treatment of chronic kidney disease (CKD) is limited, it is necessary to seek more effective and safer treatment methods, such as Chinese herbal medicines (CHMs). In order to clarify the modern theoretical basis and molecular mechanisms of CHMs, we reviewed the knowledge based on publications in peer-reviewed English-language journals, focusing on the anti-inflammatory, antioxidative, anti-apoptotic, autophagy-mediated and antifibrotic effects of CHMs commonly used in kidney disease. We also discussed recently published clinical trials and meta-analyses in this field. Based on recent studies regarding the mechanisms of kidney disease in vivo and in vitro, CHMs have anti-inflammatory, antioxidative, anti-apoptotic, autophagy-mediated, and antifibrotic effects. Several well-designed randomized controlled trials (RCTs) and meta-analyses demonstrated that the use of CHMs as an adjuvant to conventional medicines may benefit patients with CKD. Unknown active ingredients, low quality and small sample sizes of some clinical trials, and the safety of CHMs have restricted the development of CHMs. CHMs is a potential method in the treatment of CKD. Further study on the mechanism and well-conducted RCTs are urgently needed to evaluate the efficacy and safety of CHMs.

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