Use of hydrogen/deuterium exchange mass spectrometry and mutagenesis as a tool to identify the binding region of inhibitors targeting the human mitotic kinesin Eg5

2006 ◽  
Vol 20 (3) ◽  
pp. 456-462 ◽  
Author(s):  
Sébastien Brier ◽  
David Lemaire ◽  
Salvatore DeBonis ◽  
Frank Kozielski ◽  
Eric Forest
Keyword(s):  
Mass Spectrometry ◽  
Deuterium Exchange ◽  
Hydrogen Deuterium Exchange ◽  
Binding Region ◽  
Exchange Mass Spectrometry ◽  
Hydrogen Deuterium ◽  
Deuterium Exchange Mass Spectrometry ◽  
Kinesin Eg5 ◽  
Mitotic Kinesin Eg5

scholarly journals Hydrogen-Deuterium Exchange Mass Spectrometry of Phosphorylation Induced Changes in Smooth Muscle Myosin

2013 ◽  
Vol 104 (2) ◽  
pp. 452a
Author(s):  
K. Ilker Sen ◽  
Brian D. Haldeman ◽  
Richard Brizendine ◽  
Roger Mercer ◽  
Christine R. Cremo ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Smooth Muscle ◽  
Smooth Muscle Myosin ◽  
Deuterium Exchange ◽  
Hydrogen Deuterium Exchange ◽  
Exchange Mass Spectrometry ◽  
Hydrogen Deuterium ◽  
Deuterium Exchange Mass Spectrometry ◽  
Induced Changes ◽  
Muscle Myosin
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