A Bayesian analysis of pharmacoeconomic data from a clinical trial on schizophrenia

2003 ◽  
Vol 22 (6) ◽  
pp. 1025-1039 ◽  
Author(s):  
Claude Petit ◽  
Jean Maccario
Keyword(s):  
Clinical Trial ◽  
Bayesian Analysis ◽  
Pharmacoeconomic Data

scholarly journals Bayesian Scepsis About SWEPIS: Quantifying the Evidence That Early Induction of Labour Prevents Perinatal Deaths

2020 ◽  
Author(s):  
Eric-Jan Wagenmakers ◽  
Alexander Ly
Keyword(s):  
Clinical Trial ◽  
Bayesian Analysis ◽  
Randomized Clinical Trial ◽  
Clinical Studies ◽  
Expectant Management ◽  
Induction Of Labour ◽  
Perinatal Deaths ◽  
Management Group ◽  
Induction Group

In a recent randomized clinical trial, Wennerholm and colleagues compared induction of labour at 41 weeks with expectant management and induction at 42 weeks. The trial was stopped early, because six perinatal deaths occurred in the expectant management group, whereas none occurred in the induction group. Our Bayesian reanalysis finds that the SWEPIS data indeed support the hypothesis that induction of labour at 41 weeks of pregnancy is associated with a lower rate of stillbirths. However, the degree of this support is moderate at best, and arguably provides insufficient ground for terminating the study. In general, it seems hazardous to terminate clinical studies on the basis of a single P<0.05 result, without converging support of a Bayesian analysis.

scholarly journals A Bayesian Analysis of a Randomized Clinical Trial Comparing Antimetabolite Therapies for Non-Infectious Uveitis

2016 ◽  
Vol 24 (1) ◽  
pp. 63-70 ◽  
Author(s):  
Erica N. Browne ◽  
Sivakumar R. Rathinam ◽  
Anuradha Kanakath ◽  
Radhika Thundikandy ◽  
Manohar Babu ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Bayesian Analysis ◽  
Randomized Clinical Trial ◽  
Infectious Uveitis

Methisazone for prophylaxis against chickenpox; a small clinical trial

JAMA ◽  
1966 ◽  
Vol 195 (7) ◽  
pp. 586-588
Author(s):  
D. Reed
Keyword(s):  
Clinical Trial ◽  
Small Clinical Trial

Randomized clinical trial of LigasureTM versus open haemorrhoidectomy

2002 ◽  
Vol 89 (2) ◽  
pp. 154-157 ◽  
Author(s):  
F. F Palazzo ◽  
D. L Francis ◽  
M. A Clifton
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial
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