Frequency‐dependent layer‐specific differences in short‐term synaptic plasticity in the dorsal and ventral CA1 hippocampal field

Synapse ◽  
2021 ◽  
Author(s):  
Andriana Koutsoumpa ◽  
Costas Papatheodoropoulos
Keyword(s):  
Synaptic Plasticity ◽  
Short Term ◽  
Frequency Dependent ◽  
Hippocampal Field

Two Distinct Types of Corticothalamic EPSPs and Their Contribution to Short-Term Synaptic Plasticity

2003 ◽  
Vol 90 (5) ◽  
pp. 3429-3440 ◽  
Author(s):  
Jianli Li ◽  
William Guido ◽  
Martha E. Bickford
Keyword(s):  
Synaptic Plasticity ◽  
Rise Time ◽  
Type I ◽  
Type Ii ◽  
Short Term ◽  
Frequency Dependent ◽  
Nmda Glutamate Receptors ◽  
Lateral Posterior ◽  
Layer V ◽  
Stimulation Of

The lateral posterior nucleus (LPN) is innervated by two different morphological types of cortical terminals that originate from cortical layers V and VI. Here we describe two distinct types of excitatory postsynaptic potentials (EPSPs) that were recorded in the LPN after stimulation of corticothalamic fibers. These types of EPSPs differed in amplitude, latency, rise time, and response to increasing levels of stimulus intensity. The most frequently encountered EPSP, type I, displayed a longer latency and slower rise time than the less frequently encountered type II EPSP. Type I EPSPs also showed a graded increase in amplitude with increasing levels of stimulation, whereas type II EPSPs showed an all-or-none response. In response to repetitive stimulation (0.5-20 Hz), type I EPSPs displayed frequency-dependent facilitation, whereas type II EPSPs displayed frequency-dependent depression. Further details of these distinct forms of short-term synaptic plasticity were explored using paired-pulse stimuli. Pharmacology experiments revealed that both N-methyl-d-aspartate (NMDA) and non-NMDA glutamate receptors are involved in corticothalamic synaptic transmission in the LPN and contribute to both synaptic facilitation and depression. Taken together with the results of our previous anatomical studies, these results suggest that type I EPSPs arise from stimulation of layer VI afferents, whereas type II EPSPs arise from stimulation of layer V inputs. Moreover, type I and II EPSPs in the LPN may be functionally similar to corticogeniculate and retinogeniculate EPSPs, respectively.

Frequency-Dependent Modulation of Short-Term Plasticity of GABAergic Synaptic Transmission

2018 ◽  
Vol 9 (2) ◽  
pp. 119-126
Author(s):  
Oksana P. Kolesnyk ◽  
Svetlana A. Fedulova ◽  
Mycola S. Veselovsky
Keyword(s):  
Synaptic Transmission ◽  
Short Term ◽  
Frequency Dependent ◽  
Short Term Plasticity ◽  
Gabaergic Synaptic Transmission

Overexpression of synaptotagmin modulates short-term synaptic plasticity at developing neuromuscular junctions

Neuroscience ◽  
1997 ◽  
Vol 82 (4) ◽  
pp. 969-978 ◽  
Author(s):  
T Morimoto ◽  
Xin-hao Wang ◽  
Mu-ming Poo
Keyword(s):  
Synaptic Plasticity ◽  
Neuromuscular Junctions ◽  
Short Term

scholarly journals Taurine regulation of short term synaptic plasticity in fragile X mice

2010 ◽  
Vol 17 (Suppl 1) ◽  
pp. S15 ◽  
Author(s):  
Abdeslem El Idrissi ◽  
Lorenz S Neuwirth ◽  
William L’Amoreaux
Keyword(s):  
Synaptic Plasticity ◽  
Fragile X ◽  
Short Term

scholarly journals Effects of Presynaptic Calcium Stores on Short-Term Synaptic Plasticity

2012 ◽  
Vol 102 (3) ◽  
pp. 670a
Author(s):  
Suhita Nadkarni ◽  
Terence Sejnowski ◽  
Thomas Bartol ◽  
Charles Stevens ◽  
Herbert Levine ◽  
...  
Keyword(s):  
Synaptic Plasticity ◽  
Calcium Stores ◽  
Short Term ◽  
Presynaptic Calcium

scholarly journals Short-term synaptic plasticity in the deterministic Tsodyks-Markram model leads to unpredictable network dynamics

2013 ◽  
Vol 110 (41) ◽  
pp. 16610-16615 ◽  
Author(s):  
J. M. Cortes ◽  
M. Desroches ◽  
S. Rodrigues ◽  
R. Veltz ◽  
M. A. Munoz ◽  
...  
Keyword(s):  
Synaptic Plasticity ◽  
Network Dynamics ◽  
Short Term
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