Re: Non-visualization of the cavum septi pellucidi is not synonymous with agenesis of the corpus callosum. G. Malinger, D. Lev, M. Oren and T. Lerman-Sagie. Ultrasound Obstet Gynecol 2012; 40: 165-170.

ABSTRACT The corpus callosum is the main commissure of the fetal brain and can be displayed with two-dimensional (2D) and threedimensional (3D) ultrasound. However, only 3D ultrasound provides the operator with the possibility to adjust the three orthogonal planes of the brain in that way that the entire corpus callosum is shown precisely in the median plane. The aim of this article is to provide the most recent information on the assessment of the fetal corpus callosum by means of 3D ultrasound. Different topics are highlighted, such as advantage of 3D ultrasound over 2D ultrasound, indications for displaying the fetal corpus callosum, demonstration of the normal and abnormal corpus callosum and biometric measurements of the fetal corpus callosum by 3D ultrasound. Furthermore the question is raised whether fetal magnetic resonance imaging (MRI) can give additional information to the 3D ultrasound examination and whether the diagnosis resulting from 3D neurosonography gives us the chance for a better counseling of parents who are confronted with the diagnosis of a fetal corpus callosum pathology. How to cite this article Merz E, Pashaj S. What is Known about Corpus Callosum Prenatally? Donald School J Ultrasound Obstet Gynecol 2016;10(2):163-169.

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Cavum septi pellucidi (CSP) ratio: a marker for partial agenesis of the fetal corpus callosum

Ultrasound in Obstetrics and Gynecology ◽

10.1002/uog.17409 ◽

2017 ◽

Vol 50 (3) ◽

pp. 336-341 ◽

Cited By ~ 15

Author(s):

K. Karl ◽

T. Esser ◽

K. S. Heling ◽

R. Chaoui

Keyword(s):

Corpus Callosum ◽

Cavum Septi Pellucidi

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Organum cavum pre-lamina terminalis, an undescribed brain organ in rats: morphology and physiology

AJP Regulatory Integrative and Comparative Physiology ◽

10.1152/ajpregu.1991.260.2.r396 ◽

1991 ◽

Vol 260 (2) ◽

pp. R396-R406

Author(s):

S. Nicolaidis ◽

M. el Ghissassi

Keyword(s):

Angiotensin Ii ◽

Corpus Callosum ◽

High Sensitivity ◽

Ventricular System ◽

Lamina Terminalis ◽

Cavum Septi Pellucidi ◽

Brain Functions ◽

Anterior Aspect ◽

Electrolyte Homeostasis ◽

Subarachnoid Spaces

Morphological as well as physiological findings reported here point to the existence of a previously undescribed brain organ we refer to as the organum cavum pre-lamina terminalis (OCPLT). The organ is a hollow, sagittal, forebrain structure consisting of a vertical interhemispheric horn that overlies the anterior aspect of the lamina terminalis and a horizontal horn that lies in the septum below the corpus callosum. This horizontal horn was previously referred to as the cavum septi pellucidi, a vestigial anatomic curiosity. The narrow cavities of the horizontal and vertical horns join under the genu of the corpus callosum and communicate freely. The two horns do not communicate with the cerebral ventricular system or the subarachnoid spaces. Microinjections of greater than or equal to 0.2 ng angiotensin II into all regions of the cavity resulted in significant drinking, whereas injections into areas surrounding the cavities were ineffective. These data show that the organ is a discrete brain entity and displays high sensitivity to angiotensin II. These findings suggest that the OCPLT is another brain organ with significant effects on fluid and electrolyte homeostasis and perhaps other brain functions.

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