scholarly journals Histomorphometric features of hydatidiform moles in early pregnancy: relationship to detectability by ultrasound examination

2007 ◽  
Vol 29 (1) ◽  
pp. 76-80 ◽  
Author(s):  
D. J. Fowler ◽  
I. Lindsay ◽  
M. J. Seckl ◽  
N. J. Sebire
Author(s):  
Å.S. Emelyanenko , A.Yu. Blinov , T.M. Volkovskaya

The modern sonographic approach to define miscarriage in early pregnancy was shown in the article. Ultrasound diagnostic and prognostic criteria of nonviable pregnancy in early gestation were introduced. Special attention was paid to the examination`s algorithm and repeatability of ultrasound scans with suspicion of intrauterine pregnancy of uncertain viability. Also the consequences of non-following the stringent ultrasound criteria, which lead to the abortions of potentially normal pregnancies were described. Furthermore, the authors highlighted the importance of safety regulation`s aspects in ultrasound examination in early gestation. The conclusion of the importance and need in following the uniform methodological criteria in diagnostics of nonviable pregnancy has been drawn according to the analysis of world experience.


1982 ◽  
Vol 31 (3-4) ◽  
pp. 235-240 ◽  
Author(s):  
J.P. Neilson

Serial ultrasonic measurement of the biparietal diameter is an unsatisfactory means of detecting the small-for-gestational age (SGA) fetus in twin pregnancies. A new two-stage ultrasound examination schedule, highly effective in detecting the SGA singleton fetus, has been evaluated prospectively in 31 twin pregnancies. The schedule comprises ultrasonic assessment of gestational age in early pregnancy, followed by measurement of the product of the crown–rump length and trunk area of both fetuses at 34–36 weeks. All Nineteen SGA twin fetuses were detected using this schedule; the technique offers several other advantages over serial biparietal cephalometry.


Ultrasound ◽  
2008 ◽  
Vol 16 (4) ◽  
pp. 193-195 ◽  
Author(s):  
Elisabeth Ramsey ◽  
Jayne Shilitto

Background: Current national guidelines for the use of ultrasound in early pregnancy state that the embryonic heartbeat should be identified when the embryo measures 6 mm in length (RCOG/RCR 1995). Failure to visualise heart pulsations in embryos measuring 6 mm or less requires patients to wait 7 days for a repeat scan. Anecdotally, there is evidence to suggest that it is usually possible to see embryonic heart pulsation much earlier using modern ultrasound equipment. The aim of this study was to identify the smallest length of embryo when it is possible to always visualise heart pulsations during an ultrasound examination. Method: This was a prospective observational study of women attending the early pregnancy unit of a large teaching hospital. Women were invited to participate when a clinically indicated ultrasound examination revealed an intrauterine pregnancy with an embryo measuring 6 mm or less. All women were symptomatic, i.e. they presented with pain and/or bleeding in early pregnancy. The presence or absence of discernible embryonic cardiac activity was recorded at the initial ultrasound examination, and any follow-up ultrasound examination, along with the crown rump length (CRL) of the embryo. Results: The study sample consisted of 95 embryos with CRL range 1·2–6 mm. Visible heart pulsations were seen in 80 (84%) embryos at the initial examination. In 15 embryos, no discernible heart pulsation was noted; in all 15 cases, these pregnancies went on to miscarry: this was confirmed at a follow-up examination 7 days later. Conclusion: In early pregnancy ultrasound, cardiac activity should be visualized in all live embryos as soon as the embryo can be identified reliably. The absence of heart pulsations in very small embryos is indicative of pregnancy demise, regardless of the actual size of the embryo.


2021 ◽  
Author(s):  
Chen Zhou ◽  
Gengyuan Cai ◽  
Fanming Meng ◽  
Qun Hu ◽  
Guohao Liang ◽  
...  

Abstract Background Accurate early detection of pregnancy status is a prerequisite for effective monitoring of fertility in pig. In the early phase of pregnancy, because the embryo is small and in a free state, it is difficult to determine whether it is pregnant based on B-ultrasound examination. This calls for development of novel tools to accurately diagnose early pregnancy. Metabolomics reveal the metabolic status of cells, tissues and organisms. Results In this study, we investigated urinary metabolites in sows during early pregnancy. A total of 32 samples from 8 sows were collected at estrus and each phase of early pregnancy (days 9, 12, and 15 of gestation). Metabolites in urine samples from different sows obtained from gestation and estrus phases were analyzed via ultra-high performance liquid chromatography/mass spectrometry. A total of 530 metabolites were identified with high confidence in all samples. Compared with samples collected during the estrus phase, 269 differential metabolites were found in samples obtained during early pregnancy. Conclusions These metabolites included lipids and lipid-like molecules, organic acids and their derivatives, organic oxygen compounds, organoheterocyclic compounds, benzenoids, among others. These metabolites, such as choline and pregnanediol-3-glucuronide, play a very important role in pregnancy. They also regulate pregnancy in other animals. Our results provide novel insights into the metabolic changes in the urine of sows in the early pregnancy phase. The level of different metabolites in urine can be used to diagnosis pregnancy in sows. Understanding these metabolic changes is helpful for better management of pregnant sows.


Placenta ◽  
2020 ◽  
Vol 97 ◽  
pp. 65-67
Author(s):  
Eric Jauniaux ◽  
Maria Memtsa ◽  
Jemma Johns ◽  
Jackie A. Ross ◽  
Neil J. Sebire ◽  
...  

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