Backbone dynamics of the C-terminal SH2 domain of the p85α subunit of phosphoinositide 3-kinase: effect of phosphotyrosine-peptide binding and characterization of slow conformational exchange processes 1 1Edited by P. E. Wright

2000 ◽  
Vol 299 (3) ◽  
pp. 771-788 ◽  
Author(s):  
Søren M. Kristensen ◽  
Gregg Siegal ◽  
Andrew Sankar ◽  
Paul C. Driscoll
Keyword(s):  
Peptide Binding ◽  
Sh2 Domain ◽  
Conformational Exchange ◽  
Backbone Dynamics ◽  
Exchange Processes ◽  
Phosphoinositide 3 Kinase

scholarly journals Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

2014 ◽  
Vol 463 (3) ◽  
pp. 413-427 ◽  
Author(s):  
Ruzica Bago ◽  
Nazma Malik ◽  
Michael J. Munson ◽  
Alan R. Prescott ◽  
Paul Davies ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Selective Inhibitor ◽  
Class Iii ◽  
Phosphate Binding ◽  
Downstream Target ◽  
Phosphoinositide 3 Kinase ◽  
Phosphatidylinositol 3

We characterize VPS34-IN, a potent and selective inhibitor of class III Vps34 PI3K. Using VPS34-IN1, we demonstrate that PtdIns(3)P, produced by Vps34 controls phosphorylation and activity of the SGK3 protein kinase.

Solubilization and Characterization of Calcitonin Gene-Related Peptide Binding Site from Porcine Spinal Cord

1988 ◽  
Vol 50 (2) ◽  
pp. 480-485 ◽  
Author(s):  
Osamu Hiroshima ◽  
Yoshihisa Sano ◽  
Teruaki Yuzuriha ◽  
Chiyuki Yamato ◽  
Akira Saito ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Binding Site ◽  
Peptide Binding ◽  
Calcitonin Gene Related Peptide ◽  
Related Peptide ◽  
Calcitonin Gene ◽  
Peptide Binding Site

The Crystal Structures of the SH2 Domain of p56lckComplexed with Two Phosphonopeptides Suggest a Gated Peptide Binding Site

1995 ◽  
Vol 246 (2) ◽  
pp. 344-355 ◽  
Author(s):  
Vincent Mikol ◽  
Götz Baumann ◽  
Thomas H. Keller ◽  
Ute Manning ◽  
Mauro G.M. Zurini
Keyword(s):  
Binding Site ◽  
Crystal Structures ◽  
Peptide Binding ◽  
Sh2 Domain ◽  
Peptide Binding Site

A balance of redox and ligand-exchange processes in the reaction of H2[OsCl6] with thiourea: Isolation and characterization of a novel osmium complex [(NH2)2CSSC(NH2)2]2[OsIVCl6]Cl2·3H2O

2019 ◽  
Vol 484 ◽  
pp. 352-356
Author(s):  
Olga V. Rudnitskaya ◽  
Ekaterina V. Dobrokhotova ◽  
Ekaterina K. Kultyshkina ◽  
Pavel V. Dorovatovskii ◽  
Vladimir A. Lazarenko ◽  
...  
Keyword(s):  
Ligand Exchange ◽  
Isolation And Characterization ◽  
Exchange Processes

scholarly journals Characterization of Phosphoinositide-3-kinase, Class 3 (PIK3C3) Gene and Association Tests with Quantitative Traits in Pigs

2005 ◽  
Vol 18 (12) ◽  
pp. 1701-1707 ◽  
Author(s):  
J. H. Kim ◽  
B. H. Choi ◽  
H. T. Lim ◽  
E. W. Park ◽  
S. H. Lee ◽  
...  
Keyword(s):  
Quantitative Traits ◽  
Association Tests ◽  
Phosphoinositide 3 Kinase

Development of non-phosphorylated cyclic thioether peptide binding to the Grb2-SH2 domain

1999 ◽  
Vol 6 (1) ◽  
pp. 45-49 ◽  
Author(s):  
Feng-Di T. Lung ◽  
C. Richter King ◽  
Peter P. Roller
Keyword(s):  
Peptide Binding ◽  
Sh2 Domain
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