scholarly journals Recombinant Hepatitis E Capsid Protein Self-Assembles into a Dual-Domain T = 1 Particle Presenting Native Virus Epitopes

Virology ◽  
1999 ◽  
Vol 265 (1) ◽  
pp. 35-45 ◽  
Author(s):  
Li Xing ◽  
Kenzo Kato ◽  
Tiancheng Li ◽  
Naokazu Takeda ◽  
Tatsuo Miyamura ◽  
...  
Keyword(s):  
Capsid Protein ◽  
Hepatitis E ◽  
Recombinant Hepatitis ◽  
Native Virus ◽  
Dual Domain

scholarly journals Identification of two neutralization epitopes on the capsid protein of avian hepatitis E virus

2008 ◽  
Vol 89 (2) ◽  
pp. 500-508 ◽  
Author(s):  
E.-M. Zhou ◽  
H. Guo ◽  
F. F. Huang ◽  
Z. F. Sun ◽  
X. J. Meng
Keyword(s):  
Capsid Protein ◽  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Avian Hepatitis E Virus

Production and characterization of a fusion form of hepatitis E virus tORF2 capsid protein in Escherichia coli

2020 ◽  
pp. 1-8
Author(s):  
Mohamed Boumaiza ◽  
Khaled Trabelsi ◽  
Zeineb Choucha ◽  
Ines Akrouti ◽  
Serena Leone ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Capsid Protein ◽  
Hepatitis E Virus ◽  
Hepatitis E

scholarly journals The development of a recombinant hepatitis E vaccine HEV 239

2015 ◽  
Vol 11 (4) ◽  
pp. 908-914 ◽  
Author(s):  
Shao-Wei Li ◽  
Qinjian Zhao ◽  
Ting Wu ◽  
Shu Chen ◽  
Jun Zhang ◽  
...  
Keyword(s):  
Hepatitis E ◽  
Recombinant Hepatitis

scholarly journals DEVELOPMENT OF HEPATITIS E 3 GENOTYPE RECOMBINANT PROTEIN CAPSID OF: CLONING, EXPRESSION, PURIFICATION, EVALUATION OF THE ANTIGENIC PROPERTIES

2019 ◽  
Vol 1 (1) ◽  
pp. 10-17 ◽  
Author(s):  
G. I. Alatortseva ◽  
A. V. Sidorov ◽  
L. N. Nesterenko ◽  
L. N. Luhverchik ◽  
V. V. Dotsenko ◽  
...  
Keyword(s):  
Recombinant Protein ◽  
Capsid Protein ◽  
Hepatitis E ◽  
Size Exclusion ◽  
Antigenic Specificity ◽  
Clinical Samples ◽  
Genotype 3 ◽  
Recombinant Polypeptide ◽  
Antigenic Properties ◽  
Exclusion Chromatography

Aim. The development of the hepatitis E virus (HEV) genotype 3 recombinant capsid protein.Materials and methods. E.coli strains, plasmid vectors, serological and clinical samples, ELISA reagent kits, molecular biological, bioinformatic, biotechnological, biochemical and serological methods.Results. Using viruscontaining material from pigs of Belgorod region (Russian Federation) we made E.coli strains producing recombinant capsid protein, containing C-terminal of viral ORF2 protein fragment fused to E.coli β-galactosidase. Recombinant protein ORF2 had been isolated from the bacterial inclusion bodies and purified by size exclusion chromatography. Antigenic specificity of the recombinant polypeptide was confirmed by ELISA and Western blotting with sera of hepatitis E patients and reference groups (healthy donors, patients with hepatitis A, B, C, infectious mononucleosis, cytomegalovirus infection and HIV-infected patients). Conclusion. HEV genotype 3 ORF2 recombinant antigen had been developed, and the possibility to use it in diagnostic tests had been experimentally shown.

scholarly journals Chimeric Recombinant Hepatitis E Virus-like Particles as an Oral Vaccine Vehicle Presenting Foreign Epitopes

Virology ◽  
2002 ◽  
Vol 293 (2) ◽  
pp. 273-280 ◽  
Author(s):  
Masahiro Niikura ◽  
Shiki Takamura ◽  
Gisen Kim ◽  
Satoru Kawai ◽  
Masayuki Saijo ◽  
...  
Keyword(s):  
Hepatitis E Virus ◽  
Oral Vaccine ◽  
Hepatitis E ◽  
Recombinant Hepatitis ◽  
Virus Like Particles

scholarly journals Hepatitis E virus genotype 3 and capsid protein in the blood and urine of immunocompromised patients

2019 ◽  
Vol 78 (3) ◽  
pp. 232-240 ◽  
Author(s):  
Olivier Marion ◽  
Nicolas Capelli ◽  
Sebastien Lhomme ◽  
Martine Dubois ◽  
Mélanie Pucelle ◽  
...  
Keyword(s):  
Capsid Protein ◽  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Immunocompromised Patients ◽  
Genotype 3 ◽  
Virus Genotype
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