PET-CT in Colorectal Carcinoma

2010 ◽  
pp. 245-264
Author(s):  
Michael Blake ◽  
James Slattery ◽  
Dushyant Sahani ◽  
Mannudeep Kalra
Keyword(s):  
2008 ◽  
Vol 49 (3) ◽  
pp. 354-361 ◽  
Author(s):  
J. D. Soyka ◽  
P. Veit-Haibach ◽  
K. Strobel ◽  
S. Breitenstein ◽  
A. Tschopp ◽  
...  

2015 ◽  
Vol 148 (4) ◽  
pp. S-230
Author(s):  
Fanny Foubert ◽  
Michel Cherel ◽  
Alain Faivre-Chauvet ◽  
Sébastien Gouard ◽  
Catherine Maurel ◽  
...  

2008 ◽  
Vol 22 (1) ◽  
pp. 41-48 ◽  
Author(s):  
Kazumasa Inoue ◽  
Takashi Sato ◽  
Hideaki Kitamura ◽  
Masaaki Ito ◽  
Yoshiyuki Tsunoda ◽  
...  

2014 ◽  
Vol 29 (2) ◽  
pp. 157-163 ◽  
Author(s):  
Jae Pil Hwang ◽  
Sang-Keun Woo ◽  
Sang Yun Yoon ◽  
Su Young Jeong

2020 ◽  
Author(s):  
Mingyu Zhang ◽  
Jigang Yang ◽  
Hao Jiang ◽  
Huijie Jiang ◽  
Zhenchang Wang

Abstract Background The aim of this study was to investigate the relationship between multiple metabolism parameters derived from FDG and tumor TNM stages as well as tumor metastasis-associated protein of GLUT-1 and MACC1 in colorectal carcinoma (CRC). Methods 38 patients (24 male and 14 female) with primary CRC confirmed by elective surgery pathological, who also underwent 18F-FDG PET/CT scans between 2017 and 2019 were included in this study. Tumor T, N and M classification according to the 7th American Joint Committee on Cancer (AJCC). 18F-FDG parameters of SUVmax,SUVmean, TLG and MTV were measured by drawing a region of interest on the primary lesions. The expression of GLUT-1 and MACC1 was quantified by immunohistochemical and the correlation between metabolism parameters and tumor biomarkers were analyzed. Results According to our analysis, the 18F-FDG parameters of SUVmean was significantly correlated with tumor M status (P=0.000) of primary CRC. The primary tumor lesion with higher SUVmax, TLG and MTV values prone to a high-T status (P=0.002, 0.002 and 0.001, respectively). The high expression of GLUT-1/MACC1 were more frequently involved with T3-4 stage and poorly differentiated in CRC patients. Multivariate analysis found that the expression of GLUT-1 protein was correlated with SUVmax and MTV (R2=0.42, P=0.013 and 0.004, respectively), moreover, the expression of MACC1 protein was correlated with TLG (R2=0.372, P=0.000).Conclusion Glucose metabolism parameters derived from FDG provides a noninvasive assessment of M status and T status in CRC patients. The expression of GLUT-1 and MACC1 was associated with 18F-FDG uptake in CRC patients.


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