Genetic Predisposition to Critical Illness in the Pediatric Intensive Care Unit

2011 ◽  
pp. 242-261
Author(s):  
Neal J. Thomas ◽  
Mary K. Dahmer ◽  
Michael W. Quasney
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Critical Illness ◽  
Pediatric Intensive Care Unit ◽  
Genetic Predisposition ◽  
Pediatric Intensive Care

scholarly journals Evaluation of Critical Illness Polyneuropathy/Myopathy in Pediatric Intensive Care Unit

2020 ◽  
Vol 7 (3) ◽  
pp. 108-111
Author(s):  
Didar Arslan ◽  
Rıza Dinçer Yıldızdaş ◽  
Özden Özgür Horoz ◽  
Nagehan Aslan ◽  
Yasemin Çoban ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Critical Illness ◽  
Pediatric Intensive Care Unit ◽  
Pediatric Intensive Care ◽  
Critical Illness Polyneuropathy

Pediatric Chronic Critical Illness, Prolonged ICU Admissions, and Clinician Distress

2021 ◽  
Author(s):  
Alison H. Miles ◽  
Cynda H. Rushton ◽  
Brian M. Wise ◽  
Aka Moore ◽  
Renee D. Boss
Keyword(s):  
Intensive Care Unit ◽  
Content Analysis ◽  
Intensive Care ◽  
Critical Illness ◽  
Pediatric Intensive Care Unit ◽  
Pediatric Intensive Care ◽  
Goals Of Care ◽  
Chronic Critical Illness ◽  
Conventional Content Analysis ◽  
Clinical Interactions

AbstractTo gain an in-depth understanding of the experience of pediatric intensive care unit (PICU) clinicians caring for children with chronic critical illness (CCI), we conducted, audiotaped, and transcribed in-person interviews with PICU clinicians. We used purposive sampling to identify five PICU patients who died following long admissions, whose care generated substantial staff distress. We recruited four to six interdisciplinary clinicians per patient who had frequent clinical interactions with the patient/family for interviews. Conventional content analysis was applied to the transcripts resulting in the emergence of five themes: nonbeneficial treatment; who is driving care? Elusive goals of care, compromised personhood, and suffering. Interventions directed at increasing consensus, clarifying goals of care, developing systems allowing children with CCI to be cared for outside of the ICU, and improving communication may help to ameliorate this distress.

Evaluation of pediatric critical illness neuropathy/myopathy in pediatric intensive care unit

2017 ◽  
Vol 21 ◽  
pp. e207
Author(s):  
Ananthanarayanan Kasinathan ◽  
Naveen Sankhyan ◽  
Jayashree Muralidharan ◽  
Jitendra Kumar Sahu ◽  
Pratibha Singhi
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Critical Illness ◽  
Pediatric Intensive Care Unit ◽  
Pediatric Intensive Care

scholarly journals Pediatric delirium in critical illness: phenomenology, clinical correlates and treatment response in 40 cases in the pediatric intensive care unit

2007 ◽  
Vol 33 (6) ◽  
pp. 1033-1040 ◽  
Author(s):  
Jan N. M. Schieveld ◽  
Piet L. J. M. Leroy ◽  
Jim van Os ◽  
Joost Nicolai ◽  
Gijs D. Vos ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Critical Illness ◽  
Treatment Response ◽  
Pediatric Intensive Care Unit ◽  
Pediatric Intensive Care ◽  
Clinical Correlates

Acute Neuromuscular Disorders in the Pediatric Intensive Care Unit

2019 ◽  
Vol 35 (1) ◽  
pp. 17-24 ◽  
Author(s):  
Dana B. Harrar ◽  
Basil T. Darras ◽  
Partha S. Ghosh
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Respiratory Failure ◽  
Critical Illness ◽  
Myasthenia Gravis ◽  
Pediatric Intensive Care Unit ◽  
Neuromuscular Disorders ◽  
Pediatric Intensive Care ◽  
Neuromuscular Disorder ◽  
Respiratory Monitoring

Background: The neuromuscular disorders encountered in the pediatric intensive care unit (PICU) encompass a broad spectrum of pathologies. These include acute disorders (eg, Guillain-Barre syndrome), acute-on-chronic disorders (eg, myasthenia gravis), progressive disorders (eg, muscular dystrophy), and disorders that develop in the PICU (eg, critical illness myopathy/polyneuropathy). Familiarity with the presenting features of these disorders is of paramount importance in facilitating timely diagnosis. Methods: We conducted a retrospective review of the medical records of patients admitted to the PICU or Intermediate Care Program (ICP) at a single tertiary children’s hospital from 2006 to 2017 with an acute or acute-on-chronic neuromuscular disorder. We did not include patients with a known progressive neuromuscular disorder or critical illness myopathy/polyneuropathy. Results: Twenty-four patients were admitted to the PICU/ICP with acute or acute-on-chronic neuromuscular disorders. Diagnosis and indication for ICU/ICP admission were Guillain-Barre syndrome (n = 6; respiratory failure: 3, respiratory monitoring: 2, autonomic instability: 1), myasthenia gravis (n = 5; airway clearance: 3, respiratory failure: 2), acute flaccid myelitis (n = 3; respiratory failure: 2, respiratory monitoring: 1), periodic paralysis (n = 3; intravenous potassium replacement), rhabdomyolysis (n = 3; monitoring for electrolyte derangements), infant botulism (n = 2; respiratory failure), chronic demyelinating polyneuropathy (n = 1; respiratory failure), and congenital myasthenic syndrome (n = 1; apnea). No patients were admitted to the PICU/ICP with a diagnosis of tick paralysis, acute intermittent porphyria, or inflammatory myopathy. Conclusions: Although acute and acute-on-chronic neuromuscular disorders are encountered relatively rarely in the PICU, familiarity with the presenting features of these disorders is important in facilitating timely diagnosis. This, in turn, enables the institution of effective management strategies, thereby avoiding complications associated with diagnostic delays.

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