Measurement of a Surrogate Biomarker for Arginine Vasopressin Secretion in Association with Physiometric and Molecular Biomarkers of Aging

2020 ◽  
pp. 251-262
Author(s):  
Paul C. Guest ◽  
Hans-Gert Bernstein ◽  
Henrik Dobrowolny ◽  
Katrin Borucki ◽  
Sabine Westphal ◽  
...  
Keyword(s):  
Arginine Vasopressin ◽  
Molecular Biomarkers ◽  
Biomarkers Of Aging ◽  
Vasopressin Secretion

Norepinephrine regulates arginine vasopressin secretion in hypothalamic paraventricular nucleus relating with pain modulation

Neuropeptides ◽  
2009 ◽  
Vol 43 (4) ◽  
pp. 259-265 ◽  
Author(s):  
Jun Yang ◽  
Hui-Feng Yuan ◽  
Wen-Yan Liu ◽  
Xiao-Xia Zhang ◽  
Jian-Peng Feng ◽  
...  
Keyword(s):  
Paraventricular Nucleus ◽  
Arginine Vasopressin ◽  
Pain Modulation ◽  
Hypothalamic Paraventricular Nucleus ◽  
Vasopressin Secretion

Molecular Biomarkers of Aging Studies in Humans

2020 ◽  
pp. 111-123
Author(s):  
G. Pedraza-Vázquez ◽  
A. Alarcón-Aguilar ◽  
A. Luna-López
Keyword(s):  
Molecular Biomarkers ◽  
Biomarkers Of Aging ◽  
Aging Studies

scholarly journals Association of copeptin, a surrogate marker for arginine vasopressin secretion, with insulin resistance: Influence of adolescence and psychological stress

Peptides ◽  
2019 ◽  
Vol 115 ◽  
pp. 8-14 ◽  
Author(s):  
Camilla F. Thomsen ◽  
Rasmus Dreier ◽  
Tina S. Goharian ◽  
Jens P. Goetze ◽  
Lars B. Andersen ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Psychological Stress ◽  
Arginine Vasopressin ◽  
Surrogate Marker ◽  
Vasopressin Secretion

Urinary excretion of digoxin-like immunoreactive factor and arginine-vasopressin in hyper- and hypo-thyroid rats

1991 ◽  
Vol 81 (s25) ◽  
pp. 471-476 ◽  
Author(s):  
Felix Vargas ◽  
Maria J. Baz ◽  
Juan de D. Luna ◽  
Jesus Andrade ◽  
Esteban Jodar ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Hypertonic Saline ◽  
Arginine Vasopressin ◽  
Water Deprivation ◽  
Water Metabolism ◽  
Rat Urine ◽  
Urinary Levels ◽  
Vasopressin Secretion ◽  
Response To Water ◽  
Osmotic Stimuli

1. Urinary excretion of digoxin-like immunoreactive factor and arginine-vasopressin and other parameters related to salt and water metabolism were studied in hyper- and hypo-thyroid rats after different tests. 2. Urinary excretion of arginine-vasopressin was increased in hyperthyroid and reduced in hypothyroid rats with respect to controls, in response to water deprivation or a hypertonic saline load. 3. Control and hypothyroid rats showed the highest urinary excretion of digoxin-like immunoreactive factor after a hypertonic saline load. However, hyperthyroid rats had the highest urinary levels of digoxin-like immunoreactive factor under normal conditions. 4. From these results it is suggested that: (a) hyper- and hypo-thyroid rats exhibit hyper- and hypo-responsiveness of arginine-vasopressin secretion to osmotic stimuli, respectively; (b) an unidentified digoxin-like immunoreactive factor measured in unextracted rat urine may be related to diuresis and natriuresis in control and hypothyroid rats; however, dissociation between this factor and natriuresis is observed in hyperthyroid rats.

Regulation of vasopressin secretion in a patient with chronic hypernatraemia

1985 ◽  
Vol 110 (3) ◽  
pp. 346-351 ◽  
Author(s):  
Simon Smitz ◽  
Jean-Jacques Legros
Keyword(s):  
Hypertonic Saline ◽  
Arginine Vasopressin ◽  
Plasma Osmolality ◽  
Concomitant Increase ◽  
Specific Radioimmunoassay ◽  
Vasopressin Secretion ◽  
Plasma Arginine ◽  
The Brain ◽  
Unrestricted Diet ◽  
Hypertonic Saline Infusion

Abstract. A patient with the chronic hypernatraemia syndrome is described. Using a sensitive and specific radioimmunoassay, the plasma arginine-vasopressin (AVP) level was measured under various conditions. With an unrestricted diet, the plasma AVP level was inappropriately low for the degree of plasma hyperosmolality (0.9 pmol/l and 302 mOsm/kg, respectively). After chronic water loading, plasma osmolality was 271 mOsm/kg, plasma AVP level 1.5 pmol/l, and the urine remained hypertonic with respect to the plasma. During hypertonic saline infusion, plasma osmolality increased from 271 to 294 mOsm/kg without a concomitant increase in the plasma AVP concentration. After sc injection of apomorphine and after haemodynamic stimulation, the plasma AVP concentration increased from 0.8 to 36 pmol/l and from 1.2 to 6.3 pmol/I, respectively. These data demonstrate a selective deficiency in the osmoregulation of the AVP secretion. The observed neuroendocrine abnormalities may be linked to a congenital malformation of the brain.

scholarly journals Effect of naftopidil on brain noradrenaline-induced decrease in arginine-vasopressin secretion in rats

2016 ◽  
Vol 132 (1) ◽  
pp. 86-91 ◽  
Author(s):  
Masaki Yamamoto ◽  
Takahiro Shimizu ◽  
Shogo Shimizu ◽  
Youichirou Higashi ◽  
Kumiko Nakamura ◽  
...  
Keyword(s):  
Arginine Vasopressin ◽  
Brain Noradrenaline ◽  
Vasopressin Secretion

Satiety and inhibition of vasopressin secretion after drinking in dehydrated dogs

1981 ◽  
Vol 240 (4) ◽  
pp. E394-E401 ◽  
Author(s):  
T. N. Thrasher ◽  
J. F. Nistal-Herrera ◽  
L. C. Keil ◽  
D. J. Ramsay
Keyword(s):  
Arginine Vasopressin ◽  
Water Deprivation ◽  
Extracellular Fluid ◽  
Plasma Osmolality ◽  
Rapid Decline ◽  
Vasopressin Secretion

The roles of oropharyngeal and gastric factors in satiation and arginine vasopressin (AVP) secretion were examined in water-deprived dogs. Dogs were prepared with chronic gastric fistulas and received six treatments after 24 h of water deprivation: rehydration with H2O or extracellular fluid (ECF) with the fistula closed; rehydration with H2O or ECF with the fistula open; gastric administration of H2O or ECF via the fistula. Drinking occurred immediately after presentation and was always completed by 6 min. At the end of the 60-min period of observation, water was offered in order to assess the degree of satiety. No differences were observed between the volumes of H2O or ECF consumed. However, only absorption of the water drunk produced complete satiety assessed 60 min later. Drinking H2O caused a fall in plasma AVP 6 min before a detectable decline in osmolality and reached water-replete levels by 15 min after drinking. Drinking H2O or ECF plus removal via the fistula and drinking ECF also brought about a rapid decline in plasma AVP without any change in plasma osmolality. Gastric administration of H2O caused a fall in plasma AVP that coincided with the fall in osmolality, and gastric administration of ECF had no effect on plasma AVP. We conclude that oropharyngeal factors account for temporary satiety and the rapid inhibition of vasopressin secretion.

Plasma arginine vasopressin during neck suction in upright sitting man

1987 ◽  
Vol 114 (2) ◽  
pp. 243-248 ◽  
Author(s):  
P. Norsk ◽  
F. Bonde-Petersen ◽  
J. Warberg
Keyword(s):  
Arterial Pressure ◽  
Arginine Vasopressin ◽  
Venous Pressure ◽  
Haemoglobin Concentration ◽  
Plasma Osmolality ◽  
Systolic Arterial Pressure ◽  
Plasma Sodium ◽  
Fluid Restriction ◽  
Vasopressin Secretion ◽  
Plasma Arginine

Abstract. In order to examine the influence of carotid baroreceptor stimulation on arginine vasopressin secretion, 8 normal healthy males were subjected to static neck suction of −3.3 kPa for 20 min in the upright sitting position after overnight food and fluid restriction. The plasma concentration of arginine vasopressin did not change significantly during neck suction. However, in 3 subjects the termination of neck suction induced large increases in plasma arginine vasopressin from 1.8 to 63.7 ng/l, from 0.7 to 34.3 ng/l and from 2.1 to 19.0 ng/l, respectively. Two subjects experienced symptoms such as nausea and paleness during neck suction. Systolic arterial pressure increased slightly but significantly during neck suction from 15.3 ± 0.3 to 15.7 ± 0.4 kPa (N = 7, P < 0.05), whereas mean arterial pressure, diastolic arterial pressure, central venous pressure, heart rate, plasma osmolality, plasma sodium and potassium were unchanged. Haemoglobin concentration in blood and haematocrit increased significantly during and after neck suction, whereas plasma volume decreased. We conclude that neck suction with a negative pressure of 3.3 kPa in upright sitting man does not significantly affect plasma arginine vasopressin. However, termination of the stimulation induces large increases in some subjects. This may be explained by a direct effect on the vagus nerve or by a selective deloading of carotid baroreceptors.

scholarly journals Tomosyn Negatively Regulates Arginine Vasopressin Secretion in Embryonic Stem Cell-Derived Neurons

PLoS ONE ◽  
2016 ◽  
Vol 11 (10) ◽  
pp. e0164544 ◽  
Author(s):  
Seiji Takeuchi ◽  
Shintaro Iwama ◽  
Hiroshi Takagi ◽  
Atsushi Kiyota ◽  
Kohtaro Nakashima ◽  
...  
Keyword(s):  
Stem Cell ◽  
Embryonic Stem Cell ◽  
Arginine Vasopressin ◽  
Embryonic Stem ◽  
Vasopressin Secretion
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