Genome Analysis of Programmed DNA Elimination in Parasitic Nematodes

2021 ◽  
pp. 251-261
Author(s):  
Jianbin Wang
Keyword(s):  
Genome Analysis ◽  
Parasitic Nematodes ◽  
Dna Elimination

scholarly journals Comparative genome analysis of programmed DNA elimination in nematodes

2017 ◽  
Vol 27 (12) ◽  
pp. 2001-2014 ◽  
Author(s):  
Jianbin Wang ◽  
Shenghan Gao ◽  
Yulia Mostovoy ◽  
Yuanyuan Kang ◽  
Maxim Zagoskin ◽  
...  
Keyword(s):  
Genome Analysis ◽  
Comparative Genome Analysis ◽  
Comparative Genome ◽  
Dna Elimination

scholarly journals Gene silencing and sex determination by programmed DNA elimination in parasitic nematodes

2016 ◽  
Vol 32 ◽  
pp. 120-127 ◽  
Author(s):  
Adrian Streit ◽  
Jianbin Wang ◽  
Yuanyuan Kang ◽  
Richard E Davis
Keyword(s):  
Gene Silencing ◽  
Sex Determination ◽  
Parasitic Nematodes ◽  
Dna Elimination

scholarly journals Genomics of the Parasitic Nematode Ascaris and Its Relatives

Genes ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 493
Author(s):  
Jianbin Wang
Keyword(s):  
Small Rna ◽  
Drug Targets ◽  
Sex Chromosome ◽  
Model Organisms ◽  
Parasitic Nematodes ◽  
Embryonic Cells ◽  
Genomic Resources ◽  
Dna Elimination ◽  
Parasite Relationship ◽  
Host Parasite

Nematodes of the genus Ascaris are important parasites of humans and swine, and the phylogenetically related genera (Parascaris, Toxocara, and Baylisascaris) infect mammals of veterinary interest. Over the last decade, considerable genomic resources have been established for Ascaris, including complete germline and somatic genomes, comprehensive mRNA and small RNA transcriptomes, as well as genome-wide histone and chromatin data. These datasets provide a major resource for studies on the basic biology of these parasites and the host–parasite relationship. Ascaris and its relatives undergo programmed DNA elimination, a highly regulated process where chromosomes are fragmented and portions of the genome are lost in embryonic cells destined to adopt a somatic fate, whereas the genome remains intact in germ cells. Unlike many model organisms, Ascaris transcription drives early development beginning prior to pronuclear fusion. Studies on Ascaris demonstrated a complex small RNA network even in the absence of a piRNA pathway. Comparative genomics of these ascarids has provided perspectives on nematode sex chromosome evolution, programmed DNA elimination, and host–parasite coevolution. The genomic resources enable comparison of proteins across diverse species, revealing many new potential drug targets that could be used to control these parasitic nematodes.

Management of Plant-Parasitic Nematodes in Florida Cotton Production

EDIS ◽  
2017 ◽  
Vol 2017 (2) ◽  
pp. 8
Author(s):  
Zane Grabau
Keyword(s):  
Parasitic Nematodes ◽  
Cotton Production ◽  
Plant Parasitic Nematodes ◽  
Fact Sheet ◽  
Plant Parasitic

This 8-page fact sheet written by Zane J. Grabau and published in January 2017 by the UF Department of Entomology and Nematology explains how to diagnose and manage nematode problems in cotton production.­http://edis.ifas.ufl.edu/ng015

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