Axonal Pathfinding in the Developing Spinal Cord: Involvement of the Floor Plate in Chemotropic and Contact Guidance

Brain Repair ◽  
1990 ◽  
pp. 199-211
Author(s):  
T. M. Jessell ◽  
P. Bovolenta ◽  
D. Karagogeos ◽  
M. Placzek ◽  
M. Tessier-Lavigne ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Floor Plate ◽  
Contact Guidance ◽  
Axonal Pathfinding ◽  
Spinal Cord Involvement ◽  
Developing Spinal Cord

Ependymal morphogenesis in a simple vertebrate spinal cord

1993 ◽  
Vol 51 ◽  
pp. 424-425
Author(s):  
Jill K. Frey ◽  
Aileen Chen ◽  
R. David Heathcote
Keyword(s):  
Spinal Cord ◽  
Cerebrospinal Fluid ◽  
Single Layer ◽  
Central Canal ◽  
Floor Plate ◽  
Turn Of The Century ◽  
Ependymal Cells ◽  
Embryonic Spinal Cord ◽  
Developing Spinal Cord ◽  
Tyrosine Hydroxylase Immunocytochemistry

All cells of the spinal cord originate from the single layer of neuroepithelium that lines the central canal. Since the turn of the century, it has been known that a subclass of these ependymal cells can differentiate into neurons and extend cytoplasmic projections and cilia into the central canal. We have recently used tyrosine hydroxylase immunocytochemistry to identify a catecholaminergic subpopulation of cerebrospinal fluid (CSF) contacting ependymal neurons in the developing spinal cord of the frog Xenopus laevis (Fig. 1). The interneurons are located in the floor plate region of the spinal cord and have axons that extend rostrally toward the hindbrain. During the morphogenesis of the catecholaminergic population of cells, two longitudinal columns gradually appear and then rapidly “converge” at the ventral midline. Transverse sections of embryonic spinal cord (see Fig. 1) showed that the cell bodies decreased in size and underwent changes in shape, number and position within the spinal cord.

scholarly journals Floor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord

Development ◽  
2013 ◽  
Vol 140 (7) ◽  
pp. 1594-1604 ◽  
Author(s):  
K. Yu ◽  
S. McGlynn ◽  
M. P. Matise
Keyword(s):  
Spinal Cord ◽  
Sonic Hedgehog ◽  
Ependymal Cell ◽  
Floor Plate ◽  
Cell Fates ◽  
Developing Spinal Cord

Frequency of Spinal Cord Involvement and Autoantibody Status in a Large Cohort of Children Presenting with a First Acute Demyelinating Syndrome

2019 ◽  
Author(s):  
Ines El Naggar ◽  
Eva-Maria Wendel ◽  
Christian Lechner ◽  
Kathrin Schanda ◽  
Michael Karenfort ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Large Cohort ◽  
Spinal Cord Involvement ◽  
Autoantibody Status

Spinal cord involvement and paroxysmal events in “Infantile Onset Transient Hypomyelination” due to TMEM63A mutation

2021 ◽  
Author(s):  
Davide Tonduti ◽  
Eleonora Mura ◽  
Silvia Masnada ◽  
Enrico Bertini ◽  
Chiara Aiello ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Involvement

scholarly journals Dorsal commissural axon guidance in the developing spinal cord

2020 ◽  
Author(s):  
Sandy Alvarez ◽  
Supraja G. Varadarajan ◽  
Samantha J. Butler
Keyword(s):  
Spinal Cord ◽  
Axon Guidance ◽  
Commissural Axon ◽  
Developing Spinal Cord
Sign in / Sign up

Export Citation Format

Share Document