Antisense Oligonucleotides as Potential Inhibitors of Gene Expression

1993 ◽  
pp. 272-300 ◽  
Author(s):  
David M. Tidd
Keyword(s):  
Gene Expression ◽  
Antisense Oligonucleotides ◽  
Potential Inhibitors

Silencing of Gene Expression by Gymnotic Delivery of Antisense Oligonucleotides

2011 ◽  
pp. 333-346 ◽  
Author(s):  
Harris S. Soifer ◽  
Troels Koch ◽  
Johnathan Lai ◽  
Bo Hansen ◽  
Anja Hoeg ◽  
...  
Keyword(s):  
Gene Expression ◽  
Antisense Oligonucleotides

scholarly journals Modulation of human prorenin gene expression by antisense oligonucleotides in transfected CHO cells

1993 ◽  
Vol 212 (2) ◽  
pp. 347-354 ◽  
Author(s):  
Frederic CUMIN ◽  
Fred ASSELBERGS ◽  
Michele LARTIGOT ◽  
Eduard FELDER
Keyword(s):  
Gene Expression ◽  
Cho Cells ◽  
Antisense Oligonucleotides

scholarly journals Antisense oligonucleotides delivered to the amniotic cavityin uteromodulate gene expression in the postnatal mouse

2016 ◽  
pp. gkw867 ◽  
Author(s):  
Frederic F. Depreux ◽  
Lingyan Wang ◽  
Han Jiang ◽  
Francine M. Jodelka ◽  
Robert F. Rosencrans ◽  
...  
Keyword(s):  
Gene Expression ◽  
Antisense Oligonucleotides

Antisense Oligonucleotides and Myotonin Gene Expression in C2 Mouse Cells

1998 ◽  
Vol 8 (1) ◽  
pp. 25-33 ◽  
Author(s):  
M.A.B. MELONE ◽  
U. GALDERISI ◽  
G. IACOMINO ◽  
M. CIPOLLARO ◽  
G. DI BERNARDO ◽  
...  
Keyword(s):  
Gene Expression ◽  
Antisense Oligonucleotides ◽  
Mouse Cells

scholarly journals Epigenetic factors in atherogenesis: microRNA

2016 ◽  
Vol 62 (2) ◽  
pp. 134-140
Author(s):  
A.V. Smirnova ◽  
V.N. Sukhorukov ◽  
V.P. Karagodin ◽  
A.N. Orekhov
Keyword(s):  
Gene Expression ◽  
Antisense Oligonucleotides ◽  
Noncoding Rna ◽  
Cell Cycle Progression ◽  
Rna Sequences ◽  
Cycle Progression ◽  
Atherosclerosis Progression

MicroRNAs (miRNAs) are small (~22 nucleotides in length) noncoding RNA sequences regulating gene expression at posttranscriptional level. MicroRNAs bind complementarily to certain mRNA and cause gene silencing. The involvement of miRNAs in the regulation of lipid metabolism, inflammatory response, cell cycle progression and proliferation, oxidative stress, platelet activation, endothelial and vascular smooth muscle cells (VSMC) function, angiogenesis and plaque formation and rapture indicates important roles in the initiation and progression of atherosclerosis. The key role of microRNAs in pathophysiology of cardiovascular diseases (CVDs), including atherosclerosis, was demonstrated in recent studies. Creating antisense oligonucleotides is a novel technique for selective changes in gene expression both in vitro and in vivo. In this review, we draw attention to the role of miRNAs in atherosclerosis progression, using miRNA as the potential biomarkers and targets in the CVDs, as well as possible application of antisense oligonucleotides

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