Transforming Growth Factor-β Signal Transduction in the Atrioventricular Canal During Heart Development

2001 ◽  
pp. 201-219 ◽  
Author(s):  
Angelique S. Boyer ◽  
Raymond B. Runyan
Keyword(s):  
Signal Transduction ◽  
Growth Factor ◽  
Heart Development ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Atrioventricular Canal

scholarly journals NIM811 downregulates transforming growth factor-β signal transduction in vivo and in vitro

2015 ◽  
Vol 13 (1) ◽  
pp. 522-528 ◽  
Author(s):  
JING CHEN ◽  
DIAN-GANG LIU ◽  
HUI WANG ◽  
XIAO-NING WU ◽  
MIN CONG ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Growth Factor ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β

Transforming Growth Factor-β Signal Transduction

1996 ◽  
Vol 78 (2) ◽  
pp. 173-179 ◽  
Author(s):  
Thomas Brand ◽  
Michael D. Schneider
Keyword(s):  
Signal Transduction ◽  
Growth Factor ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β

Transforming Growth Factor-β Signal Transduction in Angiogenesis and Vascular Disorders

CHEST Journal ◽  
2005 ◽  
Vol 128 (6) ◽  
pp. 585S-590S ◽  
Author(s):  
Philippe Bertolino ◽  
Martine Deckers ◽  
Franck Lebrin ◽  
Peter ten Dijke
Keyword(s):  
Signal Transduction ◽  
Growth Factor ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Vascular Disorders

scholarly journals The structural basis of TGF-β, bone morphogenetic protein, and activin ligand binding

Reproduction ◽  
2006 ◽  
Vol 132 (2) ◽  
pp. 179-190 ◽  
Author(s):  
S Jack Lin ◽  
Thomas F Lerch ◽  
Robert W Cook ◽  
Theodore S Jardetzky ◽  
Teresa K Woodruff
Keyword(s):  
Signal Transduction ◽  
Growth Factors ◽  
Growth Factor ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Structural Basis ◽  
Cellular Processes ◽  
Morphogenetic Protein ◽  
Check Points ◽  
Membrane Level

The transforming growth factor-β (TGF-β) superfamily is a large group of structurally related growth factors that play prominent roles in a variety of cellular processes. The importance and prevalence of TGF-β signaling are also reflected by the complex network of check points that exist along the signaling pathway, including a number of extracellular antagonists and membrane-level signaling modulators. Recently, a number of important TGF-β crystal structures have emerged and given us an unprecedented clarity on several aspects of the signal transduction process. This review will highlight these latest advances and present our current understanding on the mechanisms of specificity and regulation on TGF-β signaling outside the cell.

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