Spermiogenesis in Sperm Genetic Integrity

2013 ◽  
pp. 201-218
Author(s):  
Marie-Chantal Grégoire ◽  
Frédéric Leduc ◽  
Guylain Boissonneault
Keyword(s):  
Genetic Integrity

scholarly journals Evaluation of genetic integrity of tomato seeds during ageing by microsatellite markers

2014 ◽  
Vol 28 (2) ◽  
pp. 29-33 ◽  
Author(s):  
I.O. Daniel ◽  
O.W. Adabale ◽  
K.A. Adeboye ◽  
E.S. Aladele ◽  
O.T. Oduoye ◽  
...  
Keyword(s):  
Microsatellite Markers ◽  
Genetic Integrity ◽  
Tomato Seeds

Legal support for the creation and use of genetic technologies in medicine

2020 ◽  
pp. 77-78
Author(s):  
В.В. Лапаева
Keyword(s):  
Human Rights ◽  
Great Britain ◽  
Human Genome ◽  
Germ Line ◽  
Genetic Integrity ◽  
Scientific Creativity ◽  
Genetic Technologies ◽  
Genomic Editing ◽  
The Given ◽  
Proper Balance

Правовая политика России в сфере создания и применения генетических технологий в медицине не обеспечивает в должной мере баланс между системой прав человека, гарантирующих защиту его достоинства и охрану здоровья, и свободой научного творчества. Несогласованность этих прав человека проявляется в том, что при отсутствии запретов на исследования с применением технологий наследуемого редактирования генома человека законодательство лишает патентоспособности любые технологии по модификации генетической целостности клеток зародышевой линии человека. Последовательный правовой подход предполагает введение ограничений на возможность геномного редактирования зародышевой линии и запрета на патентование способов такого редактирования, не выходящего за рамки заданных ограничений. При разработке такого похода целесообразно учесть опыт Великобритании. The Russian legal policy in the field of the medicine genetic technologies creation and application does not provide a proper balance between the system of human rights that guarantee the protection of its dignity and health, and the freedom of scientific creativity. The non-coordination of these human rights is manifested in the fact that in the absence of prohibitions on research using technologies of human genome inherited editing, the law deprives patentability of any technology for modifying the genetic integrity of human germline cells. A consistent legal approach involves the restrictions on the possibility of the germ line genomic editing and the prohibition of patenting the methods of such editing, which does not go beyond the given restrictions. It is advisable to take into account the experience of Great Britain.

scholarly journals Assessing hidden parentage and genetic integrity of the “United Fruit Clones” of cacao (Theobroma cacao) from Costa Rica using SNP markers

2018 ◽  
Vol 68 (5) ◽  
pp. 545-553 ◽  
Author(s):  
Allan Mata-Quirós ◽  
Adriana Arciniegas-Leal ◽  
Wilbert Phillips-Mora ◽  
Lyndel W. Meinhardt ◽  
Lambert Motilal ◽  
...  
Keyword(s):  
Costa Rica ◽  
Theobroma Cacao ◽  
Snp Markers ◽  
Genetic Integrity

Field performance evaluation and genetic integrity assessment in Argyranthemum ‘Yellow Empire’ plants recovered from cryopreserved shoot tips

2015 ◽  
Vol 51 (5) ◽  
pp. 505-513 ◽  
Author(s):  
Zhibo Zhang ◽  
Gry Skjeseth ◽  
Abdelhameed Elameen ◽  
Sissel Haugslien ◽  
Astrid Sivertsen ◽  
...  
Keyword(s):  
Performance Evaluation ◽  
Field Performance ◽  
Shoot Tips ◽  
Genetic Integrity ◽  
Integrity Assessment

Spermiogenesis in Sperm Genetic Integrity

2013 ◽  
pp. 97-114
Author(s):  
Marie-Chantal Grégoire ◽  
Frédéric Leduc ◽  
Guylain Boissonneault
Keyword(s):  
Genetic Integrity

scholarly journals Genetic integrity of four species of Leptidea (Pieridae, Lepidoptera) as sampled in sympatry in West Siberia

2015 ◽  
Vol 9 (3) ◽  
pp. 299-324 ◽  
Author(s):  
Oleg E. Kosterin ◽  
Vladimir I. Solovyev ◽  
Yuri Ilinsky
Keyword(s):  
West Siberia ◽  
Genetic Integrity

scholarly journals Manipulating the Mitochondrial Genome To Enhance Cattle Embryo Development

2017 ◽  
Vol 7 (7) ◽  
pp. 2065-2080 ◽  
Author(s):  
Kanokwan Srirattana ◽  
Justin C St. John
Keyword(s):  
Embryo Development ◽  
Nuclear Transfer ◽  
Bos Taurus ◽  
Trichostatin A ◽  
Donor Cell ◽  
Blastocyst Stage ◽  
Genetic Integrity ◽  
Rna Seq ◽  
Mtdna Copy Number ◽  
Donor Cells

Abstract The mixing of mitochondrial DNA (mtDNA) from the donor cell and the recipient oocyte in embryos and offspring derived from somatic cell nuclear transfer (SCNT) compromises genetic integrity and affects embryo development. We set out to generate SCNT embryos that inherited their mtDNA from the recipient oocyte only, as is the case following natural conception. While SCNT blastocysts produced from Holstein (Bos taurus) fibroblasts were depleted of their mtDNA, and oocytes derived from Angus (Bos taurus) cattle possessed oocyte mtDNA only, the coexistence of donor cell and oocyte mtDNA resulted in blastocysts derived from nondepleted cells. Moreover, the use of the reprogramming agent, Trichostatin A (TSA), further improved the development of embryos derived from depleted cells. RNA-seq analysis highlighted 35 differentially expressed genes from the comparison between blastocysts generated from nondepleted cells and blastocysts from depleted cells, both in the presence of TSA. The only differences between these two sets of embryos were the presence of donor cell mtDNA, and a significantly higher mtDNA copy number for embryos derived from nondepleted cells. Furthermore, the use of TSA on embryos derived from depleted cells positively modulated the expression of CLDN8, TMEM38A, and FREM1, which affect embryonic development. In conclusion, SCNT embryos produced by mtDNA depleted donor cells have the same potential to develop to the blastocyst stage without the presumed damaging effect resulting from the mixture of donor and recipient mtDNA.

The impact of stocking on the genetic integrity of Arctic charr (Salvelinus ) populations from the Alpine region

2002 ◽  
Vol 11 (6) ◽  
pp. 1017-1027 ◽  
Author(s):  
Claudia C. Englbrecht ◽  
Ulrich Schliewen ◽  
Diethard Tautz
Keyword(s):  
Arctic Charr ◽  
Alpine Region ◽  
Genetic Integrity ◽  
The Impact

Incomplete protection of genetic integrity of mature spermatozoa against oxidative stress

2011 ◽  
Vol 32 (1) ◽  
pp. 106-111 ◽  
Author(s):  
Joost O. Linschooten ◽  
Julian Laubenthal ◽  
Eduardo Cemeli ◽  
Adolf Baumgartner ◽  
Diana Anderson ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Genetic Integrity ◽  
Mature Spermatozoa
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