Antioxidant Mechanisms of Secondary Natural Products

1995 ◽  
pp. 210-237 ◽  
Author(s):  
Richard A. Larson
Keyword(s):  
Natural Products ◽  
Antioxidant Mechanisms ◽  
Secondary Natural Products

scholarly journals Marine natural products from sponges (Porifera) of the order Dictyoceratida (2013 to 2019); a promising source for drug discovery

RSC Advances ◽  
2020 ◽  
Vol 10 (57) ◽  
pp. 34959-34976
Author(s):  
Enas Reda Abdelaleem ◽  
Mamdouh Nabil Samy ◽  
Samar Yehia Desoukey ◽  
Miaomiao Liu ◽  
Ronald J. Quinn ◽  
...  
Keyword(s):  
Natural Products ◽  
Drug Discovery ◽  
Marine Natural Products ◽  
Biological Activities ◽  
Marine Organisms ◽  
Promising Source ◽  
Secondary Natural Products

Marine organisms have been considered an interesting target for the discovery of different classes of secondary natural products with wide-ranging biological activities.

ChemInform Abstract: Involvement of Diels-Alder Reactions in the Biosynthesis of Secondary Natural Products: The Late Stage of the Biosynthesis of the Phytotoxins Solanapyrones.

ChemInform ◽  
2010 ◽  
Vol 30 (38) ◽  
pp. no-no
Author(s):  
Hideaki Oikawa ◽  
Yuichi Suzuki ◽  
Kinya Katayama ◽  
Akira Naya ◽  
Chiaki Sakano ◽  
...  
Keyword(s):  
Natural Products ◽  
Late Stage ◽  
Diels Alder ◽  
Secondary Natural Products

Cytotoxic Dehydroabietylamine Derived Compounds

2020 ◽  
Vol 20 (15) ◽  
pp. 1756-1767
Author(s):  
Jana Wiemann ◽  
Ahmed Al-Harrasi ◽  
René Csuk
Keyword(s):  
Natural Products ◽  
Special Class ◽  
Biological Effects ◽  
High Potential ◽  
Scientific Interest ◽  
Poor Solubility ◽  
Biochemical Pathways ◽  
Cytotoxic Compounds ◽  
Derivatives Of ◽  
Secondary Natural Products

Background and Methods: Chemotherapy remains one of the most important methods for the treatment of cancer. More recently in this context, some products derived from natural products have raised scientific interest which especially include many terpenes. Thereby, diterpenoids represent a special class, and within this class of important secondary natural products, especially compounds derived from Dehydroabietylamine (DA), are of particular interest. Results: This review not only gives a summary of the most important findings on the cytotoxic behavior of DAderived compounds but also shows some drawbacks of these compounds, such low bioavailability and/or poor solubility of several derivatives of DA. It focusses on the chemical aspects and summarizes the DA related biological effects without deep discussion of underlying biochemical pathways. Conclusion: Dehydroabietylamine-derived cytotoxic compounds hold a high potential to be developed into efficient antitumor active drugs.

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