Effect of Hemorrhagic Shock on Gluconeogenesis, Oxygen Consumption and Redox State of Perfused Rat Liver

1973 ◽  
pp. 243-251 ◽  
Author(s):  
A. G. B. Kovách ◽  
P. Sándor
Keyword(s):  
Oxygen Consumption ◽  
Hemorrhagic Shock ◽  
Rat Liver ◽  
Redox State ◽  
Perfused Rat Liver

Intracellular Redox State and Stimulation of Gluconeogenesis by Glucagon and Norepinephrine in the Perfused Rat Liver

1980 ◽  
Vol 87 (1) ◽  
pp. 153-166 ◽  
Author(s):  
Tsukasa SUGANO ◽  
Masakazu SHIOTA ◽  
Takashi TANAKA ◽  
Yhoichi MIYAMAE ◽  
Masakazu SHIMADA ◽  
...  
Keyword(s):  
Rat Liver ◽  
Redox State ◽  
Perfused Rat Liver ◽  
Stimulation Of ◽  
Intracellular Redox

scholarly journals Changes in oxygen consumption induced by t-butyl hydroperoxide in perfused rat liver. Effect of free-radical scavengers

1984 ◽  
Vol 223 (3) ◽  
pp. 879-883 ◽  
Author(s):  
L A Videla ◽  
M I Villena ◽  
G Donoso ◽  
C Giulivi ◽  
A Boveris
Keyword(s):  
Oxygen Consumption ◽  
Free Radical ◽  
Oxygen Uptake ◽  
Rat Liver ◽  
Recovery Phase ◽  
Free Radical Scavengers ◽  
Perfused Rat Liver ◽  
Radical Scavengers ◽  
Butyl Hydroperoxide ◽  
Biphasic Effect

The addition of t-butyl hydroperoxide to perfused rat liver elicited a biphasic effect on hepatic respiration. A rapid fall in liver oxygen consumption was initially observed, followed by a recovery phase leading to respiratory rates higher than the initial steady-state values of oxygen uptake. This overshoot in hepatic oxygen uptake was abolished by free-radical scavengers such as (+)-cyanidanol-3 or butylated hydroxyanisole at concentrations that did not alter mitochondrial respiration. (+)-Cyanidanol-3 was also able to facilitate the recovery of respiration, the diminution in the calculated rate of hydroperoxide utilization and the decrease in liver GSH content produced by two consecutive pulses of t-butyl hydroperoxide. It is suggested that the t-butyl hydroperoxide-induced overshoot in liver respiration is related to increased utilization of oxygen for lipid peroxidation as a consequence of free radicals produced in the scission of the hydroperoxide by cellular haemoproteins.

OXYGEN CONSUMPTION, ASSESSED WITH THE OXYGEN ABSORPTION SPECTROPHOTOMETER, DECREASES INDEPENDENTLY OF VENOCONSTRICTION DURING HEPATIC ANAPHYLAXIS IN PERFUSED RAT LIVER

Shock ◽  
2006 ◽  
Vol 26 (1) ◽  
pp. 62-68 ◽  
Author(s):  
Sen Cui ◽  
Toshishige Shibamoto ◽  
Zonghai Ruan ◽  
Hiromichi Takano ◽  
Wei Liu ◽  
...  
Keyword(s):  
Oxygen Consumption ◽  
Rat Liver ◽  
Oxygen Absorption ◽  
Perfused Rat Liver

The Metabolite Ratio as a Function of Chloral Hydrate Dose and Intracellular Redox State in the Perfused Rat Liver

1987 ◽  
Vol 60 (5) ◽  
pp. 325-329 ◽  
Author(s):  
Toshihiro Kawamoto ◽  
Tatsuya Hobara ◽  
Haruo Kobayashi ◽  
Susumu Iwamoto ◽  
Tsunemi Sakai ◽  
...  
Keyword(s):  
Rat Liver ◽  
Redox State ◽  
Chloral Hydrate ◽  
Perfused Rat Liver ◽  
Metabolite Ratio ◽  
Intracellular Redox
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