Molecular evolution and biology of human mitochondrial DNA

Bioenergetics ◽  
1990 ◽  
pp. 373-387 ◽  
Author(s):  
Satoshi Horai ◽  
Kenji Hayasaka
Keyword(s):  
Mitochondrial Dna ◽  
Molecular Evolution ◽  
Human Mitochondrial Dna

scholarly journals Identification and in vitro capping of a primary transcript of human mitochondrial DNA.

1984 ◽  
Vol 259 (6) ◽  
pp. 3909-3915 ◽  
Author(s):  
B K Yoza ◽  
D F Bogenhagen
Keyword(s):  
Mitochondrial Dna ◽  
Primary Transcript ◽  
Human Mitochondrial Dna ◽  
In Vitro Capping

scholarly journals Mechanism of replication of human mitochondrial DNA. Localization of the 5' ends of nascent daughter strands.

1981 ◽  
Vol 256 (10) ◽  
pp. 5109-5115
Author(s):  
D.P. Tapper ◽  
D.A. Clayton
Keyword(s):  
Mitochondrial Dna ◽  
Human Mitochondrial Dna

Geographic Origin of Human Mitochondrial DNA Revisited

1992 ◽  
Vol 41 (3) ◽  
pp. 384-391 ◽  
Author(s):  
M. Stoneking ◽  
S. T. Sherry ◽  
L. Vigilant
Keyword(s):  
Mitochondrial Dna ◽  
Geographic Origin ◽  
Human Mitochondrial Dna

Human Mitochondrial DNA Polymerase Holoenzyme: Reconstitution and Characterization†

Biochemistry ◽  
2000 ◽  
Vol 39 (7) ◽  
pp. 1702-1708 ◽  
Author(s):  
Allison A. Johnson ◽  
Yu-chih Tsai ◽  
Steven W. Graves ◽  
Kenneth A. Johnson
Keyword(s):  
Mitochondrial Dna ◽  
Dna Polymerase ◽  
Human Mitochondrial Dna ◽  
Mitochondrial Dna Polymerase

scholarly journals Modular Architecture of the Hexameric Human Mitochondrial DNA Helicase

2007 ◽  
Vol 367 (5) ◽  
pp. 1382-1391 ◽  
Author(s):  
Tawn D. Ziebarth ◽  
Carol L. Farr ◽  
Laurie S. Kaguni
Keyword(s):  
Mitochondrial Dna ◽  
Dna Helicase ◽  
Modular Architecture ◽  
Human Mitochondrial Dna

Assignment of two mitochondrially synthesized polypeptides to human mitochondrial DNA and their use in the study of intracellular mitochondrial interaction

1982 ◽  
Vol 2 (1) ◽  
pp. 30-41
Author(s):  
N A Oliver ◽  
D C Wallace
Keyword(s):  
Mitochondrial Dna ◽  
Restriction Site ◽  
Mitochondrial Protein ◽  
Mitochondrial Protein Synthesis ◽  
Human Mitochondrial Dna ◽  
Ht1080 Cells ◽  
Mitochondrial Dnas ◽  
A Cell ◽  
Dna Restriction ◽  
Restriction Site Polymorphisms

Two mitochondrially synthesized marker polypeptides, MV-1 and MV-2, were found in human HeLa and HT1080 cells. These were assigned to the mitochondrial DNA in HeLa-HT1080 cybrids and hybrids by demonstrating their linkage to cytoplasmic genetic markers. These markers include mitochondrial DNA restriction site polymorphisms and resistance to chloramphenicol, an inhibitor of mitochondrial protein synthesis. In the absence of chloramphenicol, the expression of MV-1 and MV-2 in cybrids and hybrids was found to be directly proportional to the ratio of the parental mitochondrial DNAs. In the presence of chloramphenicol, the marker polypeptide linked to the chloramphenicol-sensitive mitochondrial DNA continued to be expressed. This demonstrated that resistant and sensitive mitochondrial DNAs can cooperate within a cell for gene expression and that the CAP-resistant allele was dominant or codominant to sensitive. Such cooperation suggests that mitochondrial DNAs can be exchanged between mitochondria.

Atypical clinical presentations associated with the MELAS mutation at position 3243 of human mitochondrial DNA

1993 ◽  
Vol 3 (1) ◽  
pp. 43-50 ◽  
Author(s):  
Carlos T. Moraes ◽  
Federica Ciacci ◽  
Gabriella Silvestri ◽  
Sara Shanske ◽  
Monica Sciacco ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Human Mitochondrial Dna ◽  
Clinical Presentations

Human mitochondrial DNA haplogroup M8a influences the penetrance of m.8684C>T in Han Chinese men with non-obstructive azoospermia

2018 ◽  
Vol 37 (4) ◽  
pp. 480-488 ◽  
Author(s):  
Juan Ji ◽  
Miaofei Xu ◽  
Rong Wang ◽  
Ying Wang ◽  
Yufeng Qin ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Han Chinese ◽  
Obstructive Azoospermia ◽  
Human Mitochondrial Dna ◽  
Chinese Men

scholarly journals A reanalysis of the indirect evidence for recombination in human mitochondrial DNA

Heredity ◽  
2004 ◽  
Vol 92 (4) ◽  
pp. 282-288 ◽  
Author(s):  
G Piganeau ◽  
A Eyre-Walker
Keyword(s):  
Mitochondrial Dna ◽  
Indirect Evidence ◽  
Human Mitochondrial Dna
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