The Additive Effects of Magnesium and Tartrate Upon Inhibition of Calcium Oxalate Crystal Formation in Whole Urine

1985 ◽  
pp. 847-850 ◽  
Author(s):  
P. C. Hallson ◽  
G. A. Rose
Keyword(s):  
Calcium Oxalate ◽  
Crystal Formation ◽  
Additive Effects ◽  
Calcium Oxalate Crystal ◽  
Whole Urine

Magnesium Reduces Calcium Oxalate Crystal Formation in Human Whole Urine

1982 ◽  
Vol 62 (1) ◽  
pp. 17-19 ◽  
Author(s):  
P. C. Hallson ◽  
G. A. Rose ◽  
S. Sulaiman
Keyword(s):  
Calcium Oxalate ◽  
Inverse Correlation ◽  
Normal Volunteer ◽  
Urine Samples ◽  
Magnesium Concentration ◽  
Crystal Formation ◽  
Calcium Oxalate Crystal ◽  
Isotopic Methods ◽  
Whole Urine

1. A low urinary magnesium was induced in normal volunteer subjects by giving cellulose phosphate; magnesium was added in vitro to yield urine samples of normal and high magnesium concentrations 2. After rapid evaporation of these urine samples at pH 5.3 to standard osmolality the calcium oxalate crystals were measured by microscopy and isotopic methods 3. There was a clear inverse correlation between magnesium concentration and calcium oxalate crystal formation 4. The case for treating calcium oxalate urolithiasis with magnesium is strengthened.

Studies on the role of calcium phosphate in the process of calcium oxalate crystal formation

2009 ◽  
Vol 37 (4) ◽  
pp. 181-192 ◽  
Author(s):  
Hans-Göran Tiselius ◽  
Bengt Lindbäck ◽  
Anne-Marie Fornander ◽  
Mari-Anne Nilsson
Keyword(s):  
Calcium Phosphate ◽  
Calcium Oxalate ◽  
Crystal Formation ◽  
Calcium Oxalate Crystal

scholarly journals Tamm-Horsfall protein is a critical renal defense factor protecting against calcium oxalate crystal formation

2004 ◽  
Vol 66 (3) ◽  
pp. 1159-1166 ◽  
Author(s):  
Lan Mo ◽  
Hong-Ying Huang ◽  
Xin-Hua Zhu ◽  
Ellen Shapiro ◽  
David L. Hasty ◽  
...  
Keyword(s):  
Calcium Oxalate ◽  
Crystal Formation ◽  
Calcium Oxalate Crystal

Kinetics of calcium oxalate crystal formation in urine

Urolithiasis ◽  
2016 ◽  
Vol 45 (2) ◽  
pp. 151-157 ◽  
Author(s):  
Norbert Laube ◽  
Florian Klein ◽  
Falk Bernsmann
Keyword(s):  
Calcium Oxalate ◽  
Crystal Formation ◽  
Calcium Oxalate Crystal ◽  
Kinetics Of

Inhibitory Effect of Glutamic Acid and Aspartic Acid on Calcium Oxalate Crystal Formation

1990 ◽  
Vol 17 (2) ◽  
pp. 173-177 ◽  
Author(s):  
Kenjiro Kohri ◽  
Tohru Umekawa ◽  
Mitsumasa Kodama ◽  
Yoshikazu Katayama ◽  
Yasuaki Ishikawa ◽  
...  
Keyword(s):  
Calcium Oxalate ◽  
Glutamic Acid ◽  
Aspartic Acid ◽  
Inhibitory Effect ◽  
Crystal Formation ◽  
Calcium Oxalate Crystal

Urate Does Not Influence the Formation of Calcium Oxalate Crystals in Whole Human Urine at pH 5·3

1982 ◽  
Vol 62 (4) ◽  
pp. 421-425 ◽  
Author(s):  
P. C. Hallson ◽  
G. A. Rose ◽  
S. Sulaiman
Keyword(s):  
Calcium Oxalate ◽  
Human Urine ◽  
Opposite Effect ◽  
Crystal Formation ◽  
Calcium Oxalate Crystals ◽  
Calcium Oxalate Crystal ◽  
Quantitative Microscopy ◽  
Calcium Oxalate Stones ◽  
Oxalate Crystals

1. Samples of fresh human urine were treated with immobilized uricase to lower urate concentration. Urate was added to yield low, normal and high urate samples. 2. Each sample was rapidly evaporated at pH 5.3 to standard osmolality and the yield of calcium oxalate crystals measured either by semi-quantitative microscopy or fully quantitative radioisotope techniques. 3. Increase of urinary urate did not increase the calcium oxalate crystals formed and may even have had an opposite effect. 4. Allantoin was without significant effect upon calcium oxalate crystal formation. 5. These data provide no support for the suggestion that reducing urate concentrations in the urine may be of value in treatment of patients with calcium oxalate stones.

Involvement of VKORC1 in the inhibition of calcium oxalate crystal formation in HK-2 cells

2014 ◽  
Vol 34 (3) ◽  
pp. 376-381 ◽  
Author(s):  
Bo Hu ◽  
Hao-ran Wu ◽  
Zhi-yong Ma ◽  
Zhuan-chang Wu ◽  
Ying-mei Lu ◽  
...  
Keyword(s):  
Calcium Oxalate ◽  
Crystal Formation ◽  
Calcium Oxalate Crystal

scholarly journals Effect of Macrotyloma uniflorum seeds in ethylene glycol induced urolithiasis in rats

2019 ◽  
Vol 12 (4) ◽  
pp. 43-53
Author(s):  
Vaibhavkumar B. Patel ◽  
Niyati Acharya
Keyword(s):  
Ethylene Glycol ◽  
Calcium Oxalate ◽  
Urine Volume ◽  
Crystal Formation ◽  
Significant Activity ◽  
Magnesium Citrate ◽  
Inhibitory Effects ◽  
Calcium Oxalate Crystal ◽  
Macrotyloma Uniflorum ◽  
Urine Serum

Macrotyloma uniflorum Linn. (Fabaceae) seeds are widely used for their diuretic and urolithiatic effects in India. The present study investigated the effect of aqueous extract of Macrotyloma uniflorum seeds (AEMU) on ethylene glycol induced urolithiasis in rats. To induce urolithiasis, 0.75% v/v ethylene glycol was administered orally for 14 days. The curative doses of 400 and 800 mg/kg were administered from 15th to 28th day. On 28th day, 24 hr urine, serum was collected and various biochemical parameters were estimated in urine, serum and kidney homogenate along with histology of kidney. Co-administration of AEMU with ethylene glycol has significantly (p<0.001) increased the urine volume and the level of calculus inhibitors like magnesium, citrate and decreased the level of calculus promoters like calcium, oxalate, uric acid and urea also decreased in crystallria in urine. AEMU supplement also prevented the pathological changes in kidney and increased the glomerulus activity of the kidney. These results indicate that AEMU showed significant activity in urolithiasis which might be due to its diuretic, calcium oxalate crystal formation inhibitory effects and its ability to increase the levels of inhibitors and decrease the level of promoters of urolithiasis.

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