Drug Receptors in the Lung Especially Histamine Receptors

1984 ◽  
pp. 17-29
Author(s):  
Noemi Eiser
Keyword(s):  
Histamine Receptors ◽  
Drug Receptors

scholarly journals Molecular Modeling of Histamine Receptors—Recent Advances in Drug Discovery

Molecules ◽  
2021 ◽  
Vol 26 (6) ◽  
pp. 1778
Author(s):  
Pakhuri Mehta ◽  
Przemysław Miszta ◽  
Sławomir Filipek
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Molecular Modeling ◽  
Molecular Targets ◽  
Histamine Receptors ◽  
Experimental Characterization ◽  
Complex Disorders ◽  
Theoretical Investigations ◽  
Recent Developments

The recent developments of fast reliable docking, virtual screening and other algorithms gave rise to discovery of many novel ligands of histamine receptors that could be used for treatment of allergic inflammatory disorders, central nervous system pathologies, pain, cancer and obesity. Furthermore, the pharmacological profiles of ligands clearly indicate that these receptors may be considered as targets not only for selective but also for multi-target drugs that could be used for treatment of complex disorders such as Alzheimer’s disease. Therefore, analysis of protein-ligand recognition in the binding site of histamine receptors and also other molecular targets has become a valuable tool in drug design toolkit. This review covers the period 2014–2020 in the field of theoretical investigations of histamine receptors mostly based on molecular modeling as well as the experimental characterization of novel ligands of these receptors.

Development of a homogeneous binding assay for histamine receptors

2004 ◽  
Vol 335 (1) ◽  
pp. 42-49 ◽  
Author(s):  
Kathy Crane ◽  
Daw-tsun Shih
Keyword(s):  
Binding Assay ◽  
Histamine Receptors

Autoradiographic localization of H1-histamine receptors in brain using 3H-mepyramine: Preliminary studies

1979 ◽  
Vol 58 (3) ◽  
pp. 295-304 ◽  
Author(s):  
Jose M. Palacios ◽  
W. Scott Young ◽  
Michael J. Kuhar
Keyword(s):  
Histamine Receptors

scholarly journals Studies on Drug Receptors of Smooth Muscle. V

1962 ◽  
Vol 82 (1) ◽  
pp. 6-13 ◽  
Author(s):  
Keiziro Takagi ◽  
Riitiro Iwaki
Keyword(s):  
Smooth Muscle ◽  
Drug Receptors

Histamine receptors in brain as targets for tricyclic antidepressants

1981 ◽  
Vol 2 ◽  
pp. 122-125 ◽  
Author(s):  
Jean-Charles Schwartz ◽  
Monique Garbarg ◽  
Thanh Tam Quach
Keyword(s):  
Tricyclic Antidepressants ◽  
Histamine Receptors
Sign in / Sign up

Export Citation Format

Share Document