Assessing T Follicular Helper Cell Function In Vivo: Antigen-Specific B Cell Response to Hapten and Affinity Maturation

2015 ◽  
pp. 87-101 ◽  
Author(s):  
Jessica Natt ◽  
Marion Espéli
Keyword(s):  
B Cell ◽  
Cell Response ◽  
Cell Function ◽  
Affinity Maturation ◽  
Helper Cell ◽  
Follicular Helper ◽  
T Follicular Helper Cell ◽  
B Cell Response

Author response for "Dysregulation in B cell responses and T follicular helper cell function in ADA2 deficiency patients"

2020 ◽  
Author(s):  
Francesca Schena ◽  
Federica Penco ◽  
Stefano Volpi ◽  
Claudia Pastorino ◽  
Roberta Caorsi ◽  
...  
Keyword(s):  
B Cell ◽  
Cell Function ◽  
Author Response ◽  
Helper Cell ◽  
Cell Responses ◽  
Follicular Helper ◽  
T Follicular Helper Cell ◽  
B Cell Responses

scholarly journals IL-12 receptor β1 deficiency alters in vivo T follicular helper cell response in humans

Blood ◽  
2013 ◽  
Vol 121 (17) ◽  
pp. 3375-3385 ◽  
Author(s):  
Nathalie Schmitt ◽  
Jacinta Bustamante ◽  
Laure Bourdery ◽  
Salah Eddine Bentebibel ◽  
Stephanie Boisson-Dupuis ◽  
...  
Keyword(s):  
B Cells ◽  
Cell Response ◽  
Memory B Cells ◽  
Helper Cell ◽  
Tfh Cells ◽  
Control Subjects ◽  
Follicular Helper ◽  
Key Points ◽  
T Follicular Helper Cell

Key Points IL-12Rβ1–deficient subjects displayed substantially less circulating memory Tfh and memory B cells than control subjects. The IL-12–STAT4 axis is associated with the development and functions of Tfh cells in vivo in humans.

scholarly journals Complete analysis of the B-cell response to a protein antigen, from in vivo germinal centre formation to 3-D modelling of affinity maturation

Immunology ◽  
2003 ◽  
Vol 108 (3) ◽  
pp. 274-287 ◽  
Author(s):  
Claire L. Adams ◽  
Megan K. L. Macleod ◽  
E. James Milner-White ◽  
Robert Aitken ◽  
Paul Garside ◽  
...  
Keyword(s):  
B Cell ◽  
Cell Response ◽  
Affinity Maturation ◽  
Germinal Centre ◽  
Protein Antigen ◽  
Complete Analysis ◽  
B Cell Response
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